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Tag: Diabetes: Type II

For patients with uncontrolled type 2 diabetes

Insulin Degludec/Liraglutide Noninferior to Insulin Glargine

Fixed ratio of degludec/liraglutide superior to continued titration of glargine in uncontrolled T2DM
Dispositional mindfulness seems to be associated with improved glucose regulation

Dispositional Mindfulness Tied to Improved Glucose Regulation

In adjusted analyses, no correlation for mindfulness with prevalence of type 2 diabetes
Type 2 diabetes-related genetic variants predict all-cause mortality

T2DM-Related Genetic Variants Predict All-Cause Mortality

Higher genetic risk linked to increased mortality risk, especially among obese non-Hispanic whites
Higher levels of ferritin and transferrin correlate with increased risk of type 2 diabetes among men and women

Ferritin, Transferrin Positively Linked to Type 2 Diabetes

Higher levels tied to higher risk of T2D in men and women; TSAT linked to risk in women
For obese patients with type 2 diabetes mellitus

NAFLD Linked to Unfavorable Metabolic Profile in T2DM

More severe hyperinsulinemia, dyslipidemia, and adipose tissue/hepatic insulin resistance with NAFLD
Insulin pump therapy is more effective than multiple daily injections for glycemic control in patients with type 2 diabetes

Durable Response With Insulin Pump Therapy in T2DM

Greater reduction in glycated hemoglobin with pump therapy versus multiple daily injections
A mobile phone application that provides personalized feedback to patients with type 2 diabetes can increase adherence to physical activity and improve glycemic control

App Can Up Adherence to Exercise in Diabetes

Personalized feedback via reinforcement learning improves glycemic control in type 2 diabetes
During long-term follow-up

Neutral Long-Term Effect for Intensive Glycemic Control

Follow-up of patients from ACCORD trial shows neutral effect on primary composite outcome
A protein preload enhances the glucose-lowering efficacy of vildagliptin in type 2 diabetes

Protein Preload Boosts Vildagliptin’s Effects in Diabetes

Small whey preload augments plasma intact GLP-1 levels, slows gastric emptying
Reduction in albuminuria with the renin inhibitor aliskiren may be too small to confer clinical benefit in patients with type 2 diabetes

No Benefit From Aliskiren-Tied Drops in Albuminuria

Overall albuminuria drop may be too small for cardiovascular, renal risk protection