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Tag: Diabetes: Type II

For patients with prediabetes or type 2 diabetes mellitus and nonalcoholic steatohepatitis

Long-Term Pioglitazone Safe, Effective for NASH, T2DM

Safe and effective for patients with prediabetes or type 2 diabetes and nonalcoholic steatohepatitis
Dulaglutide and glargine in combination with prandial lispro are associated with a similar percentage of time spent in the normoglycemic range

Dulaglutide, Glargine Plus Lispro Improve Glycemic Control

Dulaglutide and glargine plus lispro result in similar proportion of glucose values in normoglycemic range
The dipeptidyl peptidase-4 inhibitors vildagliptin and sitagliptin have similar effects on incretin hormone secretion

Vildagliptin, Sitagliptin Have Similar Effects on Incretin

Inter-individual variability seen in L-cell feedback induced by DPP-4 inhibitors
For patients with type 2 diabetes who are taking metformin

Varying Safety of Add-On Second-Line T2DM Treatments

For patients taking metformin, TZD and DPP-4i linked to lower mortality, cardiovascular risks
The addition of genetic risk variant data to conventional childhood risk factors improves risk assessment of impaired fasting glucose and type 2 diabetes in adulthood

Genetic Data Help ID Risk of Future Impaired Fasting Glucose

Genetic score, clinical risk factors can ID children at high risk for impaired fasting glucose, T2DM
For patients with type 2 diabetes

Even Short-Term T2DM Remission Reduces Risk of Microvascular Dz

Length of time spent in remission inversely related to risk of microvascular disease
For patients with type 2 diabetes at high cardiovascular risk

ADA: Empagliflozin Linked to Reduction in T2DM Nephropathy

Reduction in incident or worsening nephropathy, and in doubling of serum creatinine level
Genetic variants in CYP2C8 and SLCO1B1 impact the therapeutic response to rosiglitazone in patients with type 2 diabetes

CYP2C8, SLCO1B1 Variants Impact Response to Rosiglitazone

Genetic variants have clinical impact on response to rosiglitazone, but not pioglitazone
For patients with diabetic foot ulcers

Postural Instability Predicts Off-Loading Nonadherence in T2DM

Better off-loading predicted by larger and more severe DFUs, more severe neuropathy, foot pain
Sulfonylureas used as add-on therapy to metformin can maintain glycemic control in type 2 diabetes

No Significant Weight Change With Adjuvant Sulfonylureas

Addition maintains glycemic control without weight change among patients with T2DM taking metformin