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Tag: Dementia

For patients with dementia with Lewy bodies

Adjunct Zonisamide Beneficial in Dementia With Lewy Bodies

Zonisamide as an adjunct to levodopa improves parkinsonism without worsening cognitive function
Patients with various rheumatic diseases have an increased risk of dementia

Rheumatic Diseases Associated With Increased Dementia Risk

Statistical significance in Sjögren's syndrome, lupus, OA in females; SS, psoriatic arthritis, OA in males
Patterns of cortical β-amyloid and tau are not different for patients with Parkinson's disease who are cognitively normal or with mild cognitive impairment and for healthy adults

Cognitive Status Doesn’t Impact Cortical Aβ, Tau in Parkinson’s

Cortical Aβ, tau does not differ in Parkinson's patients who are cognitively normal, with MCI
Concentrations of cerebrospinal fluid β42-amyloid 42 derived from new immunoassays may show improved agreement with visual flutemetamol F18-labeled positron emission tomography assessment

Benefits for New Immunoassays for Measuring Aβ42 in CSF

May show improved correlation with mass spectrometry reference measurement procedure
Systemic inflammation in midlife is associated with future neurodegeneration and cognitive aging

Midlife Systemic Inflammation Tied to Late-Life Brain Volume

Smaller hippocampal, Alzheimer's signature region volumes seen 24 years after inflammation noted
Mid-adulthood hypertension is associated with increased risk of dementia among women but not men

Mid-Adulthood HTN Tied to Higher Dementia Risk in Women

Midlife onset of hypertension predicts 73 percent higher dementia risk versus stable normotension
Nursing home use increases with increasing cognitive impairment category

Nursing Home Use Up With Cognitive Impairment Category

One-year mortality especially high for those with prevalent dementia and any nursing home use
Magnesium levels

Magnesium Levels Tied to Dementia Risk

Both too high and too low of levels tied to increased dementia risk
For older adults

No Link for Cardiovascular Meds Use, Cognitive Impairment

No link for impaired cognition, antihypertensive, antithrombotic, lipid-modifying agent use
Lithium in drinking water is associated with the incidence of dementia in a nonlinear pattern

Lithium in Drinking Water Linked to Dementia Incidence

Significantly reduced incidence of dementia in those exposed to more than 15.0 µg/L