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Tag: Cancer: Skin

MPATH-Dx Version 2.0 Simplifies Classification of Melanoma

Updated version simplifies original five-class hierarchy into four classes, including clearly defining classes I and II lesions

Survival Rates High for Children, Teens With Melanoma

Primary tumor ulceration, head/neck location, and Breslow thickness >4 mm predict worse survival in teens

Moderna, Merck Report on Promising Melanoma Vaccine

Companies announced that the vaccine performed well in a small study of patients who had the cancer surgically removed

Tumor-Infiltrating Lymphocytes Up PFS in Advanced Melanoma

Significantly longer progression-free survival seen with infusion of tumor-infiltrating lymphocytes versus ipilimumab

2013 to 2017 Saw Significant Drop in U.S. Melanoma Mortality Rates

Significant reduction seen in mortality rate from 2013 to 2017, after the introduction of new treatments in 2011 (most after 2013)

Melanoma Diagnosis Linked to Increased Risk of Prostate Cancer

More than twofold increased risk of prostate cancer seen for men with first melanoma diagnosed 10 to 15 years before study recruitment

QOL Up With Pembrolizumab Versus Ipilimumab, HDI in Resected Melanoma

Quality of life favored the pembrolizumab arm versus standard-of-care arm receiving ipilimumab, high-dose interferon α 2b

Subset of Stage I Melanoma Patients ID’d With Very Low Mortality

Younger age at diagnosis, Clark level II linked to low risk for death among patients with stage I lesions, negative clinical nodes

Neoadjuvant Combo Immunotherapy Studied in Resectable Melanoma

In phase 2 study, relatlimab and nivolumab combination immunotherapy resulted in pathologic complete response rate of 57 percent

USPSTF: Evidence Still Lacking for Routine Skin Cancer Screening

Current evidence is insufficient for assessing balance of benefits and harms of screening for asymptomatic teens, adults