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Tag: Cancer: Skin

From 1995 to 2014

Rates of Head, Neck Melanoma Up in North American Youth

Risk for head, neck melanoma higher for male sex, older age, non-Hispanic white ethnicity
There is a dose-response association between indoor tanning and risk for cutaneous squamous cell carcinoma in women

Indoor Tanning May Up Risk for Squamous Cell Carcinoma

Dose-response association found between indoor tanning and SCC risk among women
More patients with advanced melanoma receiving nivolumab plus ipilimumab or nivolumab alone have sustained long-term survival at five years compared with those receiving ipilimumab alone

Nivolumab Therapy Prolongs Survival in Advanced Melanoma

Overall survival at five years longer with nivolumab + ipilimumab, nivolumab alone versus ipilimumab
Mohs micrographic surgery is associated with improved survival compared with traditional surgery with wide margin excision for stage I melanoma

Mohs Micrographic Surgery May Up Survival in Stage I Melanoma

Survival modestly improved compared with traditional surgery with wide margin excision
From 2001 to 2016

2001 to 2016 Saw Large Increase in Mohs Surgery for Melanoma

Regional variation considerable, with more than threefold variation between regions with highest, lowest use
Less than half of health care providers discuss sun-safe behaviors with patients

Many Providers Fail to Discuss Sun-Safe Behaviors With Patients

Skin cancer counseling often takes backseat due to lack of time, other pressing health issues
Increased dietary vitamin A seems to be associated with a reduced risk for incident cutaneous squamous cell carcinoma

Dietary Vitamin A Intake Tied to Reduced Risk for Squamous Cell Carcinoma

Cutaneous SCC risk reduced for highest versus lowest quintile of vitamin A, retinol, some carotenoids
Stratification of melanoma into groups based on calculated tumor area improves prognostic value over stratification using the category based on Breslow thickness

Calculated Tumor Area Has Prognostic Value for Melanoma

Calculated tumor area is a novel, microscopic feature and a two-dimensional surrogate for tumor size
Patients with multiple primary melanomas have worse overall survival than those with a single primary melanoma

Overall Survival Worse With Multiple Primary Melanomas

Median Breslow thickness decreased from 0.90 mm for first melanoma to 0.65 mm for second melanoma
Sharing personalized practice pattern data with physicians that is benchmarked to national data for their peers can reduce overuse of Mohs micrographic surgery among outliers

Sharing Data With Surgeons Can Reduce Overuse of Mohs Surgery

Mean stages per case reduced; reduction in Medicare spending estimated to be $11.1 million