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Tag: Cancer: Skin

The U.S. burden of skin and subcutaneous diseases is large but varies geographically

U.S. Burden of Skin and Subcutaneous Diseases Increasing

Increases seen across all 50 states, with geographic variation in percentage
For patients with melanoma treated with immune checkpoint inhibitors (ICIs)

Vitamin D May Cut Colitis Risk for Immune Checkpoint Inhibitors

Odds of developing ICI colitis significantly reduced with vitamin D use in patients with melanoma
Black patients are more likely to experience a longer delay from diagnosis to surgery versus white patients with melanoma

Racial Differences Seen in Time to Treatment for Melanoma

Time from diagnosis to definitive surgery is twice as long on average for black versus white patients
Clinically important increases in melanoma risk in patients treated with biologic therapy for common inflammatory diseases cannot be ruled out based on current evidence

Melanoma Risk From Biologic Therapy Remains Uncertain

Systematic literature review and meta-analysis reveal link to increased risk cannot be ruled out
For patients with advanced BRAFV600E/K melanoma

PFS Prolonged With Continuous Dabrafenib, Trametinib in Melanoma

Median PFS longer with continuous versus intermittent treatment, but overall survival similar
Scars from Mohs micrographic surgery for facial skin cancers are often longer than patients expect

Patients Underestimate Length of Mohs Surgery Scars

Physicians more accurately estimate scar length and can help set expectations
From 2013 to 2016

Large Decrease Seen in Melanoma Mortality From 2013 to 2016

Overall mortality decrease started in 2013 following introduction of 10 new treatments in 2011
There is a decreased risk for melanoma diagnosis among bereaved individuals but increased mortality associated with melanoma compared with nonbereaved individuals

Bereavement Tied to Higher Melanoma-Related Mortality

Authors suggest delayed diagnosis may result from lack of partner to notice skin changes
Most dermatopathologists perceive that making pathologic test result reports available to patients is a good idea

Dermatopathologists Favor Making Pathologic Reports Available

Making reports available to patients seen as good idea, but there is concern about patient worry, confusion
In the United States

High Cutaneous Melanoma Burden Found Due to UV Radiation

Burden varies across states, with highest burden seen in Hawaii