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Tag: Cancer: Prostate

Prostate multiparametric magnetic resonance imaging is feasible for predicting prostate cancer in an unselected sample of the general population

MRI Feasible for Predicting Prostate CA in Unselected Sample

Adjusted odds ratio of prostate cancer significantly higher for MRI score than PSA
For men with metastatic prostate cancer

DNA-Repair Gene Mutations ID’d in Metastatic Prostate Cancer

Prevalence of 11.8 percent for germline DNA-repair gene mutations presumed to be deleterious
Compared with 2012

Docs Tending Away From Post-Prostatectomy Adjuvant RT

Urologists in Australia less favorable toward adjuvant radiotherapy in 2015 versus 2012
Robotic-assisted laparoscopic prostatectomy is associated with reductions in positive surgical margins

Benefits for Robotic-Assisted Laparoscopic Prostatectomy

Reduced risk of positive surgical margins versus open prostatectomy for patients with pT2 disease only
From 2011 to 2013 there was a decrease in prostate cancer diagnoses

Prostate Cancer Diagnoses Down From 2011 to 2013

Use of active surveillance increasing, active treatment decreasing for low-risk disease
For men with metastatic prostate cancer

ADT Plus Radiotherapy Ups Survival in Metastatic Prostate CA

Superior median, five-year OS for prostate RT plus ADT versus ADT alone in propensity score analyses
A prostate-specific antigen cut point of ≥0.4 ng/mL predicts future disease progression

PSA Cut Point of ≥0.4 ng/mL Predicts Progression

Shows the strongest correlation between biochemical recurrence and subsequent systemic progression
For chemotherapy-naive men with metastatic castration-resistant prostate cancer

Tasquinimod Improves Radiographic PFS in mCRPC

Does not improve overall survival in metastatic castration-resistant prostate cancer
Prostate-specific antigen levels in midlife predict future lethal prostate cancer risk

Midlife PSA Levels Predict Future Lethal Prostate Cancer

PSA levels in midlife strongly predict future lethal prostate cancer risk in U.S. cohort
For men with prostate cancer

SBRT, Proton Beam Therapy Use Increasing for Prostate CA

Median cost of stereotactic body radiotherapy lower than IMRT or proton beam therapy