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Tag: Cancer: Leukemia

Donor Epstein-Barr virus serostatus influences incidence of graft-versus-host disease in patients with acute leukemia undergoing allogeneic hematopoietic stem-cell transplantation

Donor Epstein-Barr Serostatus Influences GVHD After Allo-HSCT

Higher risk of acute and chronic GVHD for patients receiving grafts from seropositive donors
Venclexta (venetoclax) has been approved by the U.S. Food and Drug Administration to treat chronic lymphocytic leukemia characterized by a specific chromosomal abnormality

FDA Approves Venclexta for CLL With 17p Deletion

Drug sanctioned for chronic lymphocytic leukemia in patients with a specific chromosomal abnormality
Emotional distress is common in children during and after therapy for childhood acute lymphoblastic leukemia

Distress Still High After Chemo Completion in Childhood ALL

Need for targeted early screening, psychosocial interventions to help patients, families at this time
Using the generic version of the cancer drug Gleevec could save patients and insurers millions of dollars

Millions in Health Costs Will Be Saved by Generic Gleevec

Over five years, researchers estimate more than $9 million in insurance savings
The CYP3A7*1C allele appears to be associated with mortality and disease progression in specific cancers

CYP3A7*1C Allele Linked to Cancer Mortality, Progression

Associated with adverse outcomes in breast cancer, lung cancer, chronic lymphocytic leukemia
A new T-cell immunotherapy has led to sustained regression in many previously relapsing and treatment-resistant cases of acute lymphoblastic leukemia

New Immune Tx Achieves Remission in B-Cell Malignancies

Patient's T cells are engineered with chimeric antigen receptors
A simple blood test may be an inexpensive

Blood Test May Help Predict Acute Myeloid Leukemia Return

Test can identify post-chemo patients with NPM1 gene mutation
Antibody therapy before stem cell transplant may benefit patients with acute leukemia

Antibody Tx Reduces Graft-vs-Host Post Stem Cell Transplant

Results for patients with acute leukemia
For patients with acute myeloid leukemia

Daily Spirometry Can Give Early Warning of Pneumonia in AML

Patient-performed daily spirometry effective for early identification in patients with acute myeloid leukemia
U.S. hematologists frequently report that the timing of end of life discussions is "too late

Hematologists Often Initiate End-of-Life Discussions Too Late

Respondents in tertiary care centers more likely to report late discussions versus community centers