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Tag: Cancer: Leukemia

For older adults with hematologic malignancies

iADL Dependency May Up Mortality in Hematologic Cancers

Instrumental activities of daily living dependency, mortality linked in seniors with hematologic cancer
For patients with chronic myeloid leukemia

Reasons for TKI Discontinuation ID’d in Chronic Myeloid Leukemia

Treatment-free remission maintained in 14 of 21 patients who discontinued tyrosine kinase inhibitors
For patients with acute myeloid leukemia

Presence of Leukemia Cutis Tied to Worse Survival in AML

Hazard ratios for leukemia-specific death, all-cause death higher for patients with AML and LC
For older patients undergoing allogeneic hematopoietic cell transplantation

Population Mortality Affects Long-Term Follow-Up of AlloHCT

Substantial part of total nonrelapse mortality for older patients due to population mortality
For patients with FMS-like tyrosine kinase 3 mutations who have relapsed or refractory acute myeloid leukemia

AACR: Longer Survival With Gilteritinib in FLT3mut+ AML

Longer overall survival, better remission rates seen for patients receiving gilteritinib versus salvage chemo
For children with B-cell precursor acute lymphoblastic leukemia with late bone marrow relapse

Favorable Outcomes Seen in Long Term for ALLR3 Trial

Findings for risk-stratified tx in B-cell precursor acute lymphoblastic leukemia, late bone marrow relapse
Almost half of elderly patients newly diagnosed with acute lymphoblastic leukemia do not receive treatment

Only About Half of Elderly Newly Diagnosed With ALL Receive Tx

53.5 percent receive treatment within 90 days; 32.4 percent receive chemo without tyrosine kinase inhibitors
Genetic variations have been identified in the ERG gene that are associated with an increased risk for acute lymphoblastic leukemia in Hispanic children

Genetic Variant Tied to Leukemia Risk in Hispanic Children

Novel susceptibility locus identified in the ERG gene for acute lymphoblastic leukemia
For children with acute lymphoblastic leukemia

Obesity Linked to Adverse Events in Children With Leukemia

Obesity ups risk for treatment-requiring hypertension, insulin-requiring hyperglycemia
For some children with hypodiploid acute lymphoblastic leukemia

Addition of BMT Not Indicated in Some With Peds Hypodiploid ALL

Bone marrow transplant not beneficial if no minimal residual dz after remission induction tx