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Tag: Cancer: Leukemia

Low bone mineral density is common in childhood leukemia and lymphoma survivors

Factors Predict Low BMD in Pediatric Blood Cancer Survivors

Low bone mineral density detected during guideline-recommended dual-energy X-ray absorptiometry
Cardiovascular adverse drug reactions occur in association with ibrutinib

Severe Adverse Cardiovascular Events Associated With Ibrutinib

Risk up for severe, sometimes fatal, events, including supraventricular arrhythmias, CNS events
Blast count seems to be the main prognostic count for patients with chronic myeloid leukemia presenting in an advanced phase

Blast Count Prognostic for CML Presenting in Advanced Phase

Mortality risk significantly higher for patients with 20 to 29 percent versus less than 20 percent blasts
Many older patients with acute myeloid leukemia do not receive any active treatment

Many Older Patients With AML Not Receiving Active Treatment

No active treatment more likely with older age, lower household income, unmarried status, comorbidities
First-degree relatives of patients with hematological malignancies have increased relative risks for the same tumor types and some different hematological malignancies

Hematological Malignancy Risk Up for First-Degree Relatives

Increased familial relative risks for the same tumor type for most hematological malignancies
A breakthrough gene therapy will be covered for certain types of lymphoma and leukemia

Medicare to Cover CAR-T Therapy for Leukemia, Lymphoma

Chimeric antigen receptor T-cell therapy boosts a patient's own immune cells
For Mexican children with acute lymphoblastic leukemia

Overweight, Obesity May Up Early Mortality Risk in Pediatric ALL

But no correlation seen for overweight or obesity with early relapse in cohort of Mexican children with ALL
For patients with previously untreated chronic lymphocytic leukemia

Ibrutinib-Rituximab Beats Chemoimmunotherapy for CLL

Progression-free, overall survival improved in the ibrutinib-rituximab group at three years
Multiple exposures to general anesthesia may be associated with neurocognitive impairment and brain imaging abnormalities in long-term survivors of childhood acute lymphoblastic leukemia

Anesthesia Tied to Neurocognitive Impairment in Childhood ALL Survivors

Survivors experience impairment with exposure to propofol, fluranes, longer anesthesia duration
A substantial proportion of older patients with high-risk acute myeloid leukemia treated with chemotherapy are long-term survivors

High Response Seen for Chemo in Seniors With High-Risk AML

Complete response rate for patients treated with chemo was 69 percent; three-year OS was 21 percent