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Tag: Cancer: Brain

There are noticeable differences in hospice utilization among patients with malignant glioma

Variation Seen in Hospice Use for Malignant Glioma

Differences by race, sex, age, level of education, urban versus rural residence identified
In patients with progressive glioblastoma

Drug Combo Doesn’t Lengthen Glioblastoma Survival

Lomustine+bevacizumab may increase progression-free, but not overall, survival versus lomustine alone
Overall survival for patients with melanoma brain metastases has improved significantly since 2000

Overall Survival Up for Melanoma Brain Metastases

Median overall survival from time of diagnosis has increased from 7.5 to 22.7 months
An experimental vaccine therapy shows promise in treating glioblastoma

Vaccine-Chemotherapy Combo Promising in Glioblastoma

Four of the 11 patients in study survived for more than five years after vaccine/chemo treatment
Adding tumor-treating fields to temozolomide is associated with improved progression-free and overall survival in glioblastoma

AACR: TTFields + Temozolomide Ups Survival in Glioblastoma

Compliance with TTFields treatment predicts outcome, with better outcome for >18 hour/day
There's no link between cytomegalovirus and glioblastoma or other high-grade gliomas

Study Finds No Link Between Cytomegalovirus, Glioblastoma

Researchers find no evidence of cytomegalovirus in tumor tissue
Treatment with autologous chimeric antigen receptor-engineered T cells targeting the tumor-associated antigen interleukin-13 receptor alpha 2 is associated with tumor regression in recurrent multifocal glioblastoma

Case Report: Adoptive T-Cell Tx Shows Promise in Glioblastoma

Tumors regressed after intracranial infusions of T cells engineered to target tumor-associated antigen
A radiomic-based approach can be used to generate a prediction model for stratifying treatment outcome among patients with recurrent glioblastoma prior to bevacizumab treatment

Radiomic-Based Method Predicts Recurrent Glioblastoma Outcome

Radiomic-based superpc signature stratifies patients into low- or high-risk groups for PFS, OS
For some metastatic brain cancer patients

Less Cognitive Deterioration With Stereotactic Radiosurgery Alone

Results seen in patients with one to three brain metastases
More extensive surgeries may best optimize patient survival in glioblastoma multiforme

Gross Total Resection for the Best Results in Glioblastoma

Although larger procedure carries more risk, odds of longer survival are higher