Home Pathology May 2016 Briefing – Pathology

May 2016 Briefing – Pathology

Here are what the editors at HealthDay consider to be the most important developments in Pathology for May 2016. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

WHO Changes Advisory Regarding Sexual Transmission of Zika

TUESDAY, May 31, 2016 (HealthDay News) — Women planning to become pregnant should wait at least eight weeks before trying to conceive if they or their partner live in — or are returning from — areas where Zika virus infections are occurring, U.N. health officials now recommend.

More Information

Next-Generation Sequencing Can ID Rare Diseases in Newborns

TUESDAY, May 31, 2016 (HealthDay News) — Next-generation sequencing may greatly improve a physician’s ability to quickly diagnose rare genetic diseases in newborns, according to research published online May 30 in CMAJ, the journal of the Canadian Medical Association.

Abstract
Full Text
Editorial (subscription or payment may be required)

ASCO Develops Recommendations for Invasive Cervical Cancer Care

TUESDAY, May 31, 2016 (HealthDay News) — The American Society for Clinical Oncology (ASCO) has developed guidelines for the management and palliative care of women with invasive cervical cancer. The clinical practice guideline was published online May 25 in the Journal of Global Oncology.

Abstract
Full Text

AHRQ Communication Toolkit Can Help After Patient Harm Occurs

TUESDAY, May 31, 2016 (HealthDay News) — A new communication toolkit created by the Agency for Healthcare Research and Quality (AHRQ) can help health care organizations and providers communicate with patients and families when harm occurs to patients.

More Information

Cephalexin Failure Rate Similar for Morbidly Obese, Non-Obese

TUESDAY, May 31, 2016 (HealthDay News) — For patients receiving cephalexin monotherapy for non-purulent cellulitis, the rate of therapeutic failure does not differ for morbidly obese and non-obese, according to a study published online May 19 in the Journal of Clinical Pharmacy and Therapeutics.

Abstract
Full Text (subscription or payment may be required)

Zika Infects, Replicates in Immune Cells From Placenta

FRIDAY, May 27, 2016 (HealthDay News) — New research, published online May 27 in Cell Host & Microbe, sheds light on how the Zika virus infects, but doesn’t kill, placenta cells.

Full Text

U.S. Has First Documented Case of Superbug Resistant to Colistin

FRIDAY, May 27, 2016 (HealthDay News) — The first case of a patient infected with a superbug resistant to a last-resort antibiotic has been documented in the United States. The report was published online May 26 in Antimicrobial Agents and Chemotherapy.

Full Text

ISG15 Deficiency Linked to Antiviral Immunity in Humans

FRIDAY, May 27, 2016 (HealthDay News) — Investigators describe a strategy for development of a broad-spectrum anti-viral agent. Their research was published online May 19 in Nature Communications.

Full Text

Remaining Uninsured May Be Difficult to Reach Via ACA

FRIDAY, May 27, 2016 (HealthDay News) — Uninsurance rates have decreased since the introduction of the Affordable Care Act (ACA), but reaching the remaining uninsured may prove challenging, according to a health policy brief published online May 23 in Health Affairs.

Full Text

Genetic Breast Cancer Risk Can Be Mediated by Healthy Lifestyle

THURSDAY, May 26, 2016 (HealthDay News) — Women who carry common gene variants linked to breast cancer can still reduce risk of the disease by following a healthy lifestyle, according to research published online May 26 in JAMA Oncology.

Abstract
Full Text
Editorial

Renal Function Decline Linked to Major Adverse CV Events

THURSDAY, May 26, 2016 (HealthDay News) — The risk of major adverse cardiovascular events (MACE) is increased with renal function decline, according to a study published online May 23 in Diabetes Care.

Full Text (subscription or payment may be required)

How Much of a Threat Will Zika Be to the United States?

THURSDAY, May 26, 2016 (HealthDay News) — Some leading insect and infectious-disease experts think health officials in the United States are overreacting to the threat posed by the Zika virus this summer.

More Information

Genetic Analysis Offers Options for Some Developmental Delay

THURSDAY, May 26, 2016 (HealthDay News) — Genetic analysis can improve diagnosis and management of intellectual developmental disorder and unexplained metabolic abnormalities, according to research published online May 25 in the New England Journal of Medicine.

Full Text (subscription or payment may be required)

Eight Immune Genes Identified As Playing a Role in Glioblastoma

THURSDAY, May 26, 2016 (HealthDay News) — Researchers have identified immune genes that may affect mortality in patients with glioblastoma multiforme, according to a study published online May 25 in Neurology.

Abstract
Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)

Prolactin Receptor Signaling Linked to Expansion of β-Cells

THURSDAY, May 26, 2016 (HealthDay News) — Prolactin receptor (PRLR) signaling plays a role in expansion of maternal β-cells during pregnancy, according to a study published online May 23 in Diabetes.

Full Text (subscription or payment may be required)

Atrial Fibrillation Linked to Cancer Risk in Women

THURSDAY, May 26, 2016 (HealthDay News) — Women with atrial fibrillation may be at an increased risk of developing cancer, particularly of the colon, according to research published online May 25 in JAMA Cardiology.

Abstract
Full Text
Editorial

Study Upholds Link Between Air Pollution and Higher CVD Risk

WEDNESDAY, May 25, 2016 (HealthDay News) — Air pollution can worsen cardiovascular disease risk factors, especially in patients with diabetes, according to a study published online May 24 in the Journal of Clinical Endocrinology & Metabolism.

Abstract
Full Text

Low Levels of Hormone Associated With Teen Obesity

WEDNESDAY, May 25, 2016 (HealthDay News) — Obese adolescents may have lower levels of the hormone spexin than normal-weight adolescents, according to research published online May 24 in the Journal of Clinical Endocrinology & Metabolism.

Abstract
Full Text

Telomere Length Not Significantly Associated With Atherosclerosis

WEDNESDAY, May 25, 2016 (HealthDay News) — Average leucocyte telomere length (LTL) and the abundance of short telomeres (percent LTL <3 kb) are not significant independent determinants of subclinical atherosclerosis, according to a study published in the May 31 issue of the Journal of the American College of Cardiology.

Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)

Chemotherapy Toxicity Predictive Model Validated

WEDNESDAY, May 25, 2016 (HealthDay News) — A predictive model for chemotherapy toxicity has been validated for older patients with solid tumors, according to a study published online May 16 in the Journal of Clinical Oncology.

Abstract
Full Text (subscription or payment may be required)

Plastics Chemical BBP Exposure May ‘Program’ Obesity

WEDNESDAY, May 25, 2016 (HealthDay News) — Benzyl butyl phthalate (BBP) regulates the mesenchymal stem cell (MSC) toward adipogenesis by inducing epigenetic stress, according to research published online May 6 in Molecular and Cellular Endocrinology.

Full Text (subscription or payment may be required)

Loss of Y Chromosome in Blood Tied to Alzheimer’s Risk in Men

TUESDAY, May 24, 2016 (HealthDay News) — Men who experience the loss of chromosome Y (LOY) from their blood cells as they age may have an increased risk of developing Alzheimer’s disease, according to a study published online May 23 in the American Journal of Human Genetics.

Full Text

Many Advanced Cancer Patients Lack Info About Their Disease

TUESDAY, May 24, 2016 (HealthDay News) — Many patients with advanced cancer lack basic information about their prognosis or treatment, according to a study published online May 23 in the Journal of Clinical Oncology.

Abstract
Full Text

Metformin Combats Adipose Tissue Expansion Via AMPK

TUESDAY, May 24, 2016 (HealthDay News) — AMPK activation by metformin is associated with inhibition of interstitial fibrosis and suppression of transforming growth factor β-1 (TGF-β1), according to a study published online May 13 in Diabetes.

Full Text (subscription or payment may be required)

Changes in Adipose Tissue With Lack of Insulin, IGF-1 Receptors

MONDAY, May 23, 2016 (HealthDay News) — Mice lacking either the insulin receptor (IR), insulin-like growth factor 1 receptor (IGF1R), or both have disruptions in white and brown adipose tissue (WAT and BAT) formation, with an almost complete absence of WAT and BAT in mice lacking both receptors, according to a study published online May 13 in Diabetes.

Full Text (subscription or payment may be required)

Urine Metabolomics Linked to Clinical Parameters of Asthma

MONDAY, May 23, 2016 (HealthDay News) — Increased urine metabolomic lipid metabolites are associated with clinical parameters in non-obese asthma patients, according to a study published online May 18 in Allergy.

Abstract
Full Text (subscription or payment may be required)

Overweight Colorectal CA Patients Display Better Survival Odds

FRIDAY, May 20, 2016 (HealthDay News) — Overweight colorectal cancer (CRC) patients may have better survival than their normal-weight peers, according to research published online May 19 in JAMA Oncology.

Abstract
Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)

Dietary Fat Intake in Adolescence May Affect Breast Density

FRIDAY, May 20, 2016 (HealthDay News) — Teens who eat high amounts of saturated fats or low amounts of healthier mono- and polyunsaturated fats tend to have denser breasts 15 years later, according to a study published online May 19 in Cancer Epidemiology, Biomarkers & Prevention.

Abstract
Full Text (subscription or payment may be required)

CDC: Many Aquatic Facilities Closed Due to Safety Violations

FRIDAY, May 20, 2016 (HealthDay News) — Serious health and safety violations force the closure of thousands of public pools, hot tubs, and water playgrounds every year, according to research published in the May 20 issue of the U.S. Centers for Disease Control and Prevention’s Morbidity and Mortality Weekly Report.

Full Text

Early Loss of Islet Sympathetic Nerves in Type 1 Diabetes

FRIDAY, May 20, 2016 (HealthDay News) — Early, marked, and sustained loss of islet sympathetic nerves is seen in type 1, but not type 2, diabetes mellitus, according to a study published online May 13 in Diabetes.

Full Text (subscription or payment may be required)

Last Year Saw 10 Percent Rise in Motorcycle Deaths in U.S

FRIDAY, May 20, 2016 (HealthDay News) — Motorcyclist deaths in the United States topped 5,000 last year — a 10 percent increase from 2014, according to a new report from the Governors Highway Safety Association.

More Information

Danazol Treatment Linked to Telomere Elongation

FRIDAY, May 20, 2016 (HealthDay News) — In patients with telomere diseases, treatment with the synthetic sex hormone danazol is associated with telomere elongation, according to a study published in the May 18 issue of the New England Journal of Medicine.

Abstract
Full Text
Editorial

Strategies Can Help Streamline Revenue-Related Processes

THURSDAY, May 19, 2016 (HealthDay News) — Strategies can be employed to maximize the amount of time available for patient care by streamlining revenue-related processes, according to the American Medical Association (AMA).

More Information

Pregabalin in Pregnancy Linked to Increased Risk of Birth Defects

THURSDAY, May 19, 2016 (HealthDay News) — The widely prescribed drug pregabalin (Lyrica) may slightly increase the risk for birth defects, according to a study published online May 18 in Neurology.

Abstract
Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)

Unrealistic Expectations for Many Men With Localized Prostate CA

THURSDAY, May 19, 2016 (HealthDay News) — Men with localized prostate cancer (LPC) often have unrealistic survival expectations, according to a study published in the May/June issue of the Annals of Family Medicine.

Abstract
Full Text

Burnout, Lack of Job Satisfaction Driving Doctors to Cut Hours

WEDNESDAY, May 18, 2016 (HealthDay News) — Full-time physicians reporting worsening burnout or decreased job satisfaction are more likely to reduce their work hours, according to a study published in the April issue of Mayo Clinic Proceedings.

Abstract
Full Text

Few Signs, Symptoms During Acute HIV-1 Infection

WEDNESDAY, May 18, 2016 (HealthDay News) — Few symptoms and signs are observed during acute HIV-1 infection, and these are most common before peak viremia, according to a study published online May 18 in the New England Journal of Medicine.

Abstract
Full Text

ASGR1 Mutation Linked to Reduced Levels of Non-HDL-C

WEDNESDAY, May 18, 2016 (HealthDay News) — ASGR1 mutation carriers have reduced levels of non-high-density lipoprotein cholesterol (HDL-C) and reduced risk of coronary artery disease, according to a study published online May 18 in the New England Journal of Medicine.

Abstract
Full Text
Editorial

Cancer Treatment Lacking for HIV-Infected Patients

WEDNESDAY, May 18, 2016 (HealthDay News) — While powerful HIV medications are allowing patients to live longer, these same patients are less likely to get treatment for cancer if it develops, according to a study published online May 17 in Cancer.

Abstract
Full Text (subscription or payment may be required)

IOM Committee Finds Genetically Engineered Crops Safe

WEDNESDAY, May 18, 2016 (HealthDay News) — Crops created through genetic engineering are as safe to eat as crops developed through traditional plant-breeding methods, according to the National Academies of Sciences, Engineering, and Medicine.

More Information

Sexual Harassment Experienced by One-Third of Female Doctors

WEDNESDAY, May 18, 2016 (HealthDay News) — Thirty percent of female physicians face sexual harassment on the job, while close to three-quarters perceive gender bias at work and two-thirds say they have actually experienced it, according to survey findings published in the May 17 issue of the Journal of the American Medical Association.

Full Text (subscription or payment may be required)

Simultaneous Diagnosis of SLE, Pheochromocytoma Described

TUESDAY, May 17, 2016 (HealthDay News) — A case of simultaneous diagnosis of systemic lupus erythematous (SLE) and pheochromocytoma, with disappearance of SLE after pheochromocytoma treatment, is described in a letter to the editor published online May 6 in the International Journal of Rheumatic Diseases.

Full Text (subscription or payment may be required)

HDL-C Prediction of Heart Disease Modulated by TG, LDL-C

TUESDAY, May 17, 2016 (HealthDay News) — The impact of high-density lipoprotein cholesterol (HDL-C) on cardiovascular disease (CVD) risk is modulated by triglycerides (TG) and low-density lipoprotein cholesterol (LDL-C), according to a study published online May 10 in Circulation: Cardiovascular Quality and Outcomes.

Abstract
Full Text (subscription or payment may be required)

Obesity, RYGB Impact Skeletal Muscle Proteome

TUESDAY, May 17, 2016 (HealthDay News) — Obesity and Roux-en-Y gastric bypass (RYGB) affect the skeletal muscle proteome, with changes in protein abundance in skeletal muscle before and after RYGB surgery, according to a study published online May 10 in Diabetes.

Abstract
Full Text (subscription or payment may be required)

Physical Activity Associated With Lower Risk of Many Cancers

MONDAY, May 16, 2016 (HealthDay News) — Exercise may significantly reduce risk for many types of cancer, according to a large review published online May 16 in JAMA Internal Medicine.

Abstract
Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)

Trans-Resveratrol, Hesperetin Up Glo1 Expression, Metabolic Health

MONDAY, May 16, 2016 (HealthDay News) — For overweight and obese subjects, trans-resveratrol (tRES) and hesperetin (HESP) coformulation increases glyoxalase 1 (Glo1) expression and produces improvements in metabolic and vascular health, according to a study published online May 11 in Diabetes.

Abstract
Full Text (subscription or payment may be required)

Novel Index Predicts Survival After Chemo in Pancreatic Cancer

MONDAY, May 16, 2016 (HealthDay News) — For patients with advanced pancreatic cancer receiving chemotherapy, the systemic inflammation response index (SIRI), based on peripheral neutrophil, monocyte, and lymphocyte counts, can predict survival, according to a study published online May 6 in Cancer.

Abstract
Full Text (subscription or payment may be required)

Neuronal GHS-R Involved in Regulating Energy Metabolism

FRIDAY, May 13, 2016 (HealthDay News) — Neuronal growth hormone secretagogue receptor (GHS-R) is involved in regulating energy metabolism, according to an experimental study published online May 10 in Diabetes.

Abstract
Full Text (subscription or payment may be required)

Oophorectomy Tied to Increased Risk of Colorectal Cancer

FRIDAY, May 13, 2016 (HealthDay News) — Oophorectomy may lead to increased risk of developing colorectal cancer, according to research reported in the June issue of the British Journal of Surgery.

Abstract
Full Text (subscription or payment may be required)

CAM Use May Affect Breast Cancer Patients’ Chemo Decisions

FRIDAY, May 13, 2016 (HealthDay News) — Women with early-stage breast cancer who utilize complementary and alternative medicine (CAM) may delay recommended chemotherapy, according to research published online May 12 in JAMA Oncology.

Abstract
Full Text
Editorial

Temporary Skin Tattoos Can Evoke Delayed Hypersensitivity

FRIDAY, May 13, 2016 (HealthDay News) — Black henna, used in temporary skin tattoos, can evoke type IV delayed hypersensitivity reactions, according to an article published online April 27 in BMJ Case Reports.

Abstract
Full Text

Infection Control Measures Established for Ebola Care

THURSDAY, May 12, 2016 (HealthDay News) — Infection control measures have been developed to strengthen hospitals’ capacity for safely diagnosing and treating patients with Ebola virus disease (EVD), according to a review published online May 10 in the Annals of Internal Medicine.

Full Text (subscription or payment may be required)

Adolescent Fruit Consumption May Impact Breast Cancer Risk

THURSDAY, May 12, 2016 (HealthDay News) — Teenage girls who consume large amounts of fruit may lower their future risk for breast cancer; however, women who drink more alcohol over time might increase their breast cancer risk, according to two studies published online May 11 in The BMJ.

Full Text 1
Full Text 2
Editorial

Zika May Present With Mucocutaneous Features

THURSDAY, May 12, 2016 (HealthDay News) — In one recent case of Zika virus infection, a diffuse papular descending eruption, petechiae on the palate, and hyperemic sclerae were key symptoms of infection with the mosquito-borne virus, according to a case report published online May 11 in JAMA Dermatology.

Abstract
Full Text

New Insight Might Aid Diagnosis, Treatment of Sjögren’s Syndrome

THURSDAY, May 12, 2016 (HealthDay News) — Rab3D and Rab27 proteins play an important role in the enhanced release of cathepsin S (CTSS) from lacrimal gland acinar cells (LGAC) in Sjögren’s syndrome (SS), according to an experimental study published online April 13 in the American Journal of Physiology-Cell Physiology.

Full Text (subscription or payment may be required)

Use of Disease-Monitoring Tests Often Extreme in Breast Cancer

THURSDAY, May 12, 2016 (HealthDay News) — More than one in three women with metastatic breast cancer (MBC) are extreme users of disease-monitoring tests, with higher total health care costs seen in association with extreme use, according to a study published online May 9 in the Journal of Clinical Oncology.

Abstract
Full Text

Metreleptin Ups Resting-State Connectivity in Lipodystrophy

WEDNESDAY, May 11, 2016 (HealthDay News) — For patients with lipodystrophy (LD), resting-state connectivity is significantly increased in three brain areas with metreleptin treatment, with decreased hunger feelings and diminished incentive value of food, according to a study published online May 10 in Diabetes.

Abstract
Full Text (subscription or payment may be required)

CDC Updates Zika Testing Guidance for Urine Samples

TUESDAY, May 10, 2016 (HealthDay News) — The interim diagnostic testing guidance for Zika virus in public health laboratories has been updated, according to a report published in the May 10 early-release issue of the U.S. Centers for Disease Control and Prevention’s Morbidity and Mortality Weekly Report.

Full Text

Agreement High for Prognostic Cancer Screening Tools

TUESDAY, May 10, 2016 (HealthDay News) — For cancer screening in Medicare beneficiaries, there is substantial agreement for different prognostic tools for short- and long-term survival, according to a study published online April 30 in the Journal of the American Geriatrics Society.

Abstract
Full Text (subscription or payment may be required)

Genetic Variants ID Treatment Response in Psoriasis

TUESDAY, May 10, 2016 (HealthDay News) — Genetic variants have been identified in psoriasis patients that correlate with anti-tumor necrosis factor (TNF)-α treatment response, according to research published online April 30 in the Journal of Dermatology.

Abstract
Full Text (subscription or payment may be required)

Pesticides May Raise Risk of Amyotrophic Lateral Sclerosis

TUESDAY, May 10, 2016 (HealthDay News) — Exposure to pesticides and other chemicals may increase the risk for amyotrophic lateral sclerosis (ALS), according to a study published online May 9 in JAMA Neurology.

Abstract
Full Text
Editorial (subscription or payment may be required)

Microbiome Linked to Infectious Complications in AML

MONDAY, May 9, 2016 (HealthDay News) — For patients with acute myelogenous leukemia (AML) undergoing induction chemotherapy (IC), gastrointestinal microbiome composition is associated with infectious complications, according to a study published online May 3 in Cancer.

Abstract
Full Text (subscription or payment may be required)

CDC Establishes New ‘Clean Hands Count’ Campaign

MONDAY, May 9, 2016 (HealthDay News) — The U.S. Centers for Disease Control and Prevention has introduced a new campaign, “Clean Hands Count,” to encourage health care professionals, patients, and patients’ families to keep their hands clean in order to prevent health care-associated infections.

More Information

Regular Aspirin Use May Protect Against Bile Duct Cancer

MONDAY, May 9, 2016 (HealthDay News) — Regular aspirin use may lower the risk of bile duct cancer, according to a study published online April 26 in Hepatology.

Abstract
Full Text (subscription or payment may be required)

Portable, Rapid, Low-Cost Zika Test Shows Promise in Monkeys

FRIDAY, May 6, 2016 (HealthDay News) — A fast, inexpensive test that detects the Zika virus in monkeys might be useful for doctors working far from hospitals, according to a study published online May 6 in Cell.

Full Text

New Evidence of Link Between Zika and Guillain-Barré

FRIDAY, May 6, 2016 (HealthDay News) — There is new evidence that Zika may cause Guillain-Barré syndrome, according to findings presented at the U.S. Centers for Disease Control and Prevention’s Epidemic Intelligence Service Conference, held from May 2 to 5 in Atlanta.

More Information

Climate Change May Lead to Higher Prevalence of CKD

FRIDAY, May 6, 2016 (HealthDay News) — Climate change may increase rates of chronic kidney disease worldwide as rising temperatures and heat stress damage kidneys, according to research published online May 5 in the Clinical Journal of the American Society of Nephrology.

Abstract
Full Text (subscription or payment may be required)

Substantial Aggregate Costs of Care for Cervical Cancer

FRIDAY, May 6, 2016 (HealthDay News) — The costs of care for cervical cancer vary by phase of care, and aggregate costs are substantial, according to a study published in the May issue of the American Journal of Obstetrics & Gynecology.

Abstract
Full Text (subscription or payment may be required)

Fluconazole Use May Raise Risk of Certain Birth Defects

THURSDAY, May 5, 2016 (HealthDay News) — Prenatal use of low-dose fluconazole is associated with cleft lip with cleft palate and d-transposition of the great arteries, according to a study published in the May issue of the American Journal of Obstetrics & Gynecology.

Abstract
Full Text (subscription or payment may be required)

CDC: Hepatitis C Leads Infectious Disease Mortality in U.S.

THURSDAY, May 5, 2016 (HealthDay News) — The number of hepatitis C-linked deaths in the United States reached a record high in 2014, and the disease is now the leading cause of infectious disease mortality in the United States, according to a report published in the May 15 issue of Clinical Infectious Diseases.

Abstract
Full Text (subscription or payment may be required)
More Information

No Link for Tea, Coffee Intake With Barrett’s Esophagus

THURSDAY, May 5, 2016 (HealthDay News) — After adjustment for confounding variables there is no correlation between the risk of Barrett’s esophagus (BE) and tea or coffee consumption, according to a study published in the May issue of Clinical Gastroenterology and Hepatology.

Abstract
Full Text
Editorial

Physician Leadership Training May Help Counteract Burnout

WEDNESDAY, May 4, 2016 (HealthDay News) — Physician leaders with good leadership qualities are more likely to have employees who are satisfied and do not show signs of burnout, according to a study published in the April issue of the Mayo Clinic Proceedings and a report published by the American Medical Association.

More Information

Bacterium Blocks Zika Virus Isolates in Aedes Mosquitoes

WEDNESDAY, May 4, 2016 (HealthDay News) — Experiments in mosquitoes suggest that bacteria may help curb the spread of the Zika virus, according to research published online May 4 in Cell Host & Microbe.

Abstract
Full Text

Radon in the Home Linked to Hematologic Malignancies

WEDNESDAY, May 4, 2016 (HealthDay News) — There appears to be a strong link between exposure to high levels of radon in the home and women’s risk of hematologic malignancies, according to a study published online recently in Environmental Research.

Full Text (subscription or payment may be required)

Herpes Simplex Virus Linked to Frailty, Mortality

WEDNESDAY, May 4, 2016 (HealthDay News) — For older women, herpes simplex virus antibody levels are associated with incident frailty and mortality, according to a study published online April 30 in the Journal of the American Geriatrics Society.

Abstract
Full Text (subscription or payment may be required)

Mitochondrial Dysfunction May Explain Prostate Cancer Disparity

WEDNESDAY, May 4, 2016 (HealthDay News) — Improper mitochondrial functioning may account for prostate cancer treatment resistance in African-American (AA) men, according to a study published online April 26 in the British Journal of Cancer.

Abstract
Full Text (subscription or payment may be required)

Adiposity Genetic Risk Score Tied to Cardiometabolic Health

WEDNESDAY, May 4, 2016 (HealthDay News) — Data from a large cohort have replicated the association between the genetic risk score of 11 favorable adiposity variants with lower risk of cardiometabolic disease, according to research published online April 26 in Diabetes.

Abstract
Full Text (subscription or payment may be required)

Price Transparency Tool Doesn’t Cut Health Care Spending

WEDNESDAY, May 4, 2016 (HealthDay News) — Employee use of a price transparency tool does not cut health care spending, according to a study published in the May 3 issue of the Journal of the American Medical Association.

Abstract
Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)

USPSTF: Evidence Lacking for Celiac Disease Screening

TUESDAY, May 3, 2016 (HealthDay News) — The U.S. Preventive Services Task Force (USPSTF) concludes that the current evidence is insufficient to weigh the potential benefits and harms of screening for celiac disease in asymptomatic individuals. These findings form the basis of a draft recommendation statement published online May 3 by the USPSTF.

Draft Evidence Review
Draft Recommendation Statement
Comment on Recommendation

Infant Viral Infections Might Raise Risk of Type 1 Diabetes

TUESDAY, May 3, 2016 (HealthDay News) — Respiratory and viral infections in the first six months of life may increase the odds of a child developing type 1 diabetes by nearly 20 percent, according to a study published in the May 3 issue of the Journal of the American Medical Association.

Full Text (subscription or payment may be required)

Well Water a Suspected Cause of Bladder Cancer in New England

TUESDAY, May 3, 2016 (HealthDay News) — Arsenic in drinking water from private wells may explain the elevated bladder cancer risk among people in three New England states, according to a study published online May 2 in the Journal of the National Cancer Institute.

Abstract
Full Text (subscription or payment may be required)

Report: Why Health Care Costs Are Lower in Europe Than U.S.

TUESDAY, May 3, 2016 (HealthDay News) — European residents have access to the same health care services as U.S. residents but pay much less, and this is related to several specific factors, according to a report published by INDIGOMED on April 25.

Full Text

2017 May Offer Fewer Choices for Affordable Care Act Enrollees

MONDAY, May 2, 2016 (HealthDay News) — With the nation’s largest health insurer exiting all but a few Affordable Care Act exchanges next year, some Americans may be left with fewer choices and some might see higher monthly premiums.

More Information

Markers That Predict Omalizumab Response Identified

MONDAY, May 2, 2016 (HealthDay News) — Baseline serum periostin levels and levels of serum free immunoglobulin E (IgE) during treatment follow-up may be useful in assessing response to omalizumab treatment for asthma, according to a study published online April 26 in Allergy.

Abstract
Full Text (subscription or payment may be required)

Glaucoma May Result From White Matter Degeneration

MONDAY, May 2, 2016 (HealthDay News) — Glaucoma may be associated with lower fractional anisotropy in the optic radiations, forceps major, and corpus callosum, possibly as a result of white matter degeneration, according to a study published online April 25 in Ophthalmic & Physiological Optics.

Abstract
Full Text

Updated Recs Aim to Expand Primary Aldosteronism Screening

MONDAY, May 2, 2016 (HealthDay News) — The Endocrine Society has issued new guidelines intended to increase screening for primary aldosteronism. The Clinical Practice Guideline was published online March 2 in The Journal of Clinical Endocrinology & Metabolism.

Abstract
Full Text (subscription or payment may be required)

Serum Prolactin in Pregnancy Predicts Prediabetes/Diabetes

MONDAY, May 2, 2016 (HealthDay News) — Serum prolactin in pregnancy predicts the risk of postpartum prediabetes/diabetes, according to a study published online April 26 in Diabetes Care.

Abstract
Full Text (subscription or payment may be required)

Aneurysmal Bone Cyst Can Present As Subungual Mass

MONDAY, May 2, 2016 (HealthDay News) — In a case report published online April 23 in the Journal of Cutaneous Pathology, a subungual aneurysmal bone cyst is described in a 39-year-old male patient.

Abstract
Full Text (subscription or payment may be required)

Copyright © 2016 ScoutNews, LLC. All rights reserved.