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Low Dose Protocol Cuts Patient Exposure to Radiation During PCI

Significant reduction of kerma area product and air kerma at interventional reference point in LDP group

FRIDAY, Dec. 30, 2016 (HealthDay News) — A lose dose protocol (LDP) can reduce patient radiation exposure during percutaneous coronary intervention (PCI), according to a study published in the Jan. 15 issue of The American Journal of Cardiology.

Davide Maccagni, R.T., from San Raffaele Hospital in Milan, and colleagues examined the effectiveness and impact of a radiological LDP in terms of reducing exposure to radiation during PCI. Nine hundred six consecutive patients who underwent PCI between November 2014 and October 2015 were assessed: 63 percent were treated with standard dose protocol (SDP; 15 frames/second for cine acquisition and standard settings for fluoroscopy) and 37 percent with the LDP (7.5 frames/second for cine acquisition and low-dose settings for fluoroscopy).

The researchers found that there was a significant reduction of kerma area product and air kerma at interventional reference point in the LDP group (both P < 0.0001). There were marked differences relating to the exceeding of International Commission on Radiological Protection and National Council on Radiation Protection and Measurements’ air kerma at interventional reference point trigger level; these were significantly lower in the LDP group (P < 0.0001). In complex PCI these differences were more relevant.

“The implementation of LDP allowed a marked reduction in patient dosimetric parameters for PCI and significantly reduced the risk of exceeding the International Commission on Radiological Protection/National Council on Radiation Protection and Measurements trigger levels for potential skin injuries,” the authors write.

Two authors disclosed financial ties to Direct Flow Medical; one author disclosed ties to Medtronic.

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