Home Pathology December 2016 Briefing – Pathology

December 2016 Briefing – Pathology

Here are what the editors at HealthDay consider to be the most important developments in Pathology for December 2016. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

Uric Acid May Mark Progression for Nasopharyngeal Cancer

FRIDAY, Dec. 30, 2016 (HealthDay News) — There is a direct correlation between the pretreatment serum uric acid (SUA) level and tumor progression in patients with locally advanced nasopharyngeal carcinoma (NPC), according to a study published online Dec. 20 in Head & Neck.

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Aqueous Humor VEGF Levels Up With Prostaglandin for Glaucoma

FRIDAY, Dec. 30, 2016 (HealthDay News) — Vascular endothelial growth factor (VEGF) levels are significantly higher in the aqueous humor of diabetes mellitus (DM) patients and glaucoma patients who used prostaglandin agents, according to a letter to the editor published online Dec. 23 in Clinical & Experimental Ophthalmology.

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Panel of 88 SNPs Predicts Breast CA Risk in Women at High Risk

FRIDAY, Dec. 30, 2016 (HealthDay News) — A panel of 88 single nucleotide polymorphisms (SNPs) can predict breast cancer risk, according to a study published online Dec. 28 in the Journal of Clinical Oncology.

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Pharmacy-Based Sale of Chlamydia Test Kits Is Effective

FRIDAY, Dec. 30, 2016 (HealthDay News) — It is feasible to sell chlamydia test kits through pharmacies and use existing health infrastructure to follow up on results and manage clients, according to a pilot study published online Dec. 23 in the Journal of Pharmacy Practice and Research.

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Case Report: Adoptive T-Cell Tx Shows Promise in Glioblastoma

THURSDAY, Dec. 29, 2016 (HealthDay News) — Treatment with autologous chimeric antigen receptor (CAR)-engineered T cells targeting the tumor-associated antigen interleukin-13 receptor alpha 2 (IL13Rα2) is associated with tumor regression in recurrent multifocal glioblastoma, according to a case report published in the Dec. 29 issue of the New England Journal of Medicine.

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Triple-Negative Breast CA Risk Up for Blacks With Benign Breast Dz

THURSDAY, Dec. 29, 2016 (HealthDay News) — African-American (AA) identity is associated with increased risk of triple-negative breast cancer (TNBC) among women with a prior diagnosis of benign breast disease (BBD), according to a study published online Dec. 22 in JAMA Oncology.

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Age-Adjusted Cut-Offs in D-Dimer Testing for PE Cause Concern

THURSDAY, Dec. 29, 2016 (HealthDay News) — D-dimer unit type should be clarified and laboratories interested in implementing age-adjusted D-dimer (AADD) cut-offs should use only specific D-dimer assays that have been adequately assessed in clinical studies, according to an Ideas and Opinions piece published online Dec. 27 in the Annals of Internal Medicine.

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Gastric Bypass Associated With Reduced Risk of Psoriasis

WEDNESDAY, Dec. 28, 2016 (HealthDay News) — Gastric bypass, but not gastric banding, is associated with reduced risk of psoriasis, progression to severe psoriasis, and psoriatic arthritis, according to a study published online Dec. 21 in JAMA Surgery.

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Personal Health Care Spending Continues to Soar in the U.S.

TUESDAY, Dec. 27, 2016 (HealthDay News) — From 1996 to 2013 there were considerable increases in personal health care spending in the United States, with the highest amounts for diabetes, ischemic heart disease, and low back and neck pain, according to a study published in the Dec. 27 issue of the Journal of the American Medical Association.

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Oxidative Stress Tied to Early-Onset Androgenetic Alopecia

TUESDAY, Dec. 27, 2016 (HealthDay News) — Younger patients with early-onset androgenetic alopecia (AGA) have increased oxidative stress, according to a study published online Dec. 16 in the Journal of Cosmetic Dermatology.

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Confocal Microscopy Aids Surgical Removal of Tumors From Eyelid

TUESDAY, Dec. 27, 2016 (HealthDay News) — Imaging using fluorescence confocal microscopy (FCM) analysis in the reflectance mode and with an “en face” scanning can control tumor margins of eyelid basal cell carcinoma (BCC) to optimize surgical management, according to a study published online Dec. 19 in Clinical & Experimental Ophthalmology.

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Recombinant Type-5 Vector-Based Ebola Vaccine Safe

TUESDAY, Dec. 27, 2016 (HealthDay News) — For healthy adults from Sierra Leon, the recombinant type-5 vector-based Ebola vaccine is safe and immunogenic, according to a study published online Dec. 21 in The Lancet.

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Less Intense Surveillance OK for Some Prostate Cancer Cases

FRIDAY, Dec. 23, 2016 (HealthDay News) — Certain patients on active surveillance for prostate cancer may be eligible for less intensive surveillance, according to a study published in the January issue of The Journal of Urology.

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Chronic Hepatitis B Prevalence Higher in Those With T2DM

FRIDAY, Dec. 23, 2016 (HealthDay News) — Patients with type 2 diabetes have higher prevalence of chronic hepatitis B virus infection (CHB), according to a study published online Dec. 8 in the Journal of Diabetes Investigation.

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ASCO Updates Guideline for SNB in Early-Stage Breast Cancer

THURSDAY, Dec. 22, 2016 (HealthDay News) — Recommendations for use of sentinel node biopsy (SNB) in early-stage breast cancer are unchanged from 2014, according to a clinical practice guideline update published online Dec. 12 in the Journal of Clinical Oncology.

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Higher Oxidative Stress Linked to Metabolic Syndrome

THURSDAY, Dec. 22, 2016 (HealthDay News) — Oxidized low-density lipoprotein (ox-LDL) as a proxy for oxidative stress is associated with metabolic syndrome (MetS) and its components, according to a study published online Dec. 19 in Diabetes.

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Mesenchymal Stem Cells Show Promise for Torn Meniscus

THURSDAY, Dec. 22, 2016 (HealthDay News) — Undifferentiated autologous mesenchymal stem cells (MSCs) seeded onto a collagen scaffold (MSC/collagen-scaffold) shows promise for patients with torn meniscus, according to a study published online Dec. 15 in Stem Cells Translational Medicine.

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Single-Dose LMWH Can Interfere With Algorithm for DVT Diagnosis

THURSDAY, Dec. 22, 2016 (HealthDay News) — A single dose of low-molecular-weight heparin (LMWH) given the previous day can reduce D-dimer and potentially risk non-identification of a deep vein thrombosis (DVT), according to a research letter published online Dec. 15 in the International Journal of Laboratory Hematology.

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Pritelivir Beats Valacyclovir for Genital HSV-2 Shedding

WEDNESDAY, Dec. 21, 2016 (HealthDay News) — The novel herpes simplex virus (HSV) helicase-primase inhibitor pritelivir is more effective than valacyclovir for reducing genital HSV-2 shedding, according to a study published in the Dec. 20 issue of the Journal of the American Medical Association.

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Incidence of Nontyphoidal Salmonella Infections Estimated

WEDNESDAY, Dec. 21, 2016 (HealthDay News) — There are about 6,200 resistant culture-confirmed nontyphoidal Salmonella infections annually, according to a study published in the January issue of the U.S. Centers for Disease Control and Prevention’s Emerging Infectious Diseases.

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Higher AlphaB-Crystallin Levels Linked to Diabetic Retinopathy

WEDNESDAY, Dec. 21, 2016 (HealthDay News) — Vitreous levels of alphaB-crystallin are significantly higher in eyes of patients with proliferative diabetic retinopathy (PDR) compared to the eyes of controls without diabetes, according to a study published online Dec. 7 in Clinical & Experimental Ophthalmology.

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Mouthwash May Be Useful for Gonorrhea Control

WEDNESDAY, Dec. 21, 2016 (HealthDay News) — Listerine mouthwash may be potentially useful for gonorrhea control, according to a study published online Dec. 20 in Sexually Transmitted Infections.

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Peripartum Aortic Dissection Risk Factors Examined in Marfan Sx

WEDNESDAY, Dec. 21, 2016 (HealthDay News) — Pregnant patients with Marfan syndrome, particularly those with a dilating aortic root, are at high risk of aortic dissection during and following pregnancy, according to a study published in the Jan. 1 issue of The American Journal of Cardiology.

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CDC: Fatal Drug Overdoses Up Significantly in the United States

TUESDAY, Dec. 20, 2016 (HealthDay News) — Drug overdose deaths increased 23 percent between 2010 and 2014, with 47,055 Americans dying in 2014, according to findings published in the Dec. 20 issue of the U.S. Centers for Disease Control and Prevention’s National Vital Statistics Reports.

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USPSTF Recommends Against Routine HSV Screening

TUESDAY, Dec. 20, 2016 (HealthDay News) — The U.S. Preventive Services Task Force (USPSTF) recommends against routine serologic screening for genital herpes simplex virus (HSV) infection in asymptomatic adolescents and adults, according to an final recommendation statement published in the Dec. 20 issue of the Journal of the American Medical Association.

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MicroRNAs 203 and 205 Are Prognostic in Cutaneous SCC

TUESDAY, Dec. 20, 2016 (HealthDay News) — MicroRNAs (miR-203 and miR-205) could be useful prognostic markers in cutaneous squamous cell carcinoma, with distinct expression and associations, according to a study published online Dec. 11 in the British Journal of Dermatology.

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Pathologists Vary in Suggested Therapy for Melanocytic Lesions

TUESDAY, Dec. 20, 2016 (HealthDay News) — Pathologists have wide variability in treatment suggestions for melanocytic lesions, according to a study published in the January issue of the Journal of the American Academy of Dermatology.

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Health Care Provider Burnout Negatively Affects Quality, Safety

TUESDAY, Dec. 20, 2016 (HealthDay News) — Health care provider burnout is negatively associated with quality and safety of health care, according to a meta-analysis published recently in the Journal of General Internal Medicine.

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No Link for Transfused Red Blood Cell Storage, Mortality

MONDAY, Dec. 19, 2016 (HealthDay News) — For patients who received transfusions in Sweden and Denmark from 2003 to 2012, there was no correlation between the length of red blood cell (RBC) storage and mortality, according to a study published online Dec. 20 in the Annals of Internal Medicine.

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DEA Announces Critical Changes in Registration Renewal Process

MONDAY, Dec. 19, 2016 (HealthDay News) — The Drug Enforcement Administration (DEA) has announced critical changes in its registration renewal process, according to a report published by the American Academy of Family Physicians.

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Noncardiovascular Cause of Death More Common in CHD Patients

MONDAY, Dec. 19, 2016 (HealthDay News) — For patients with coronary heart disease (CHD), mortality is more often due to noncardiovascular causes, according to a study published in the Jan. 1 issue of The American Journal of Cardiology.

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Diabetes Ups Risk of HCC, Death in Patients With Hepatitis C

MONDAY, Dec. 19, 2016 (HealthDay News) — For hepatitis C virus (HCV)-infected patients, diabetes mellitus (DM) is associated with increased risk of hepatocellular carcinoma (HCC) development and all-cause mortality, according to a study published online Dec. 8 in the Journal of Gastroenterology and Hepatology.

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Long-Term DPP4-Inhibitor Use Not Tied to Fracture Risk in T2DM

MONDAY, Dec. 19, 2016 (HealthDay News) — For patients with type 2 diabetes mellitus (T2DM), long-term use of dipeptidyl peptidase-4 inhibitors (DPP4-Is) is not associated with fracture risk, according to a study published online Dec. 10 in Diabetes, Obesity and Metabolism.

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Dysglycemia Affects Brain Structure, Cognition in Seniors

MONDAY, Dec. 19, 2016 (HealthDay News) — In older adults, dysglycemia is associated with brain structure and cognition, according to a study published online Dec. 5 in the Journal of the American Geriatrics Society.

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Cervicovaginal Secretions Contain HIV-Linked Immune Mediators

MONDAY, Dec. 19, 2016 (HealthDay News) — Cervicovaginal secretions from pregnant and nonpregnant women contain HIV infectivity-linked immune mediators, although there is no difference in infectivity between pregnant and nonpregnant women, according to a study published in the December issue of the American Journal of Obstetrics & Gynecology.

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BRCA Testing, Not Mastectomies, Up After Angelina Jolie Editorial

FRIDAY, Dec. 16, 2016 (HealthDay News) — After actress Angelina Jolie’s 2013 New York Times editorial that announced her preventive double mastectomy, there was an increase in the number of women who were tested for the BRCA genes but no corresponding increase in mastectomy rates, according to research published in the Christmas 2016 issue of the The BMJ.

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BRCA1/2, ATM Mutations ID Risk for Lethal Prostate Cancer

FRIDAY, Dec. 16, 2016 (HealthDay News) — The rate of germline BRCA1/2 and ATM mutations is significantly higher among patients with lethal prostate cancer (PCa) and is an independent predictor of lethal PCa, according to a study published online Dec. 15 in European Urology.

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Old Age Should Not Exclude Deceased Organ Donation

FRIDAY, Dec. 16, 2016 (HealthDay News) — Healthy kidneys from elderly donors are often rejected, but even kidneys from donors 80 and older can function for years after transplantation, according to a study published online Dec. 15 in the Clinical Journal of the American Society of Nephrology.

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CRC in Patients Under 50 Often Caused by Genetic Mutations

FRIDAY, Dec. 16, 2016 (HealthDay News) — As many as one in six colorectal cancer patients under the age of 50 have genetic traits that greatly increase the risk of cancer, according to a study published online Dec. 15 in JAMA Oncology.

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MRI Has a Role to Play After Negative Prostate Biopsy

THURSDAY, Dec. 15, 2016 (HealthDay News) — Magnetic resonance imaging (MRI) and MRI-targeted biopsies have a role in the diagnosis and treatment of patients with a prior negative prostate biopsy, according to a review published in the December issue of The Journal of Urology.

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Bacterial Cause of Periodontal Disease May Drive RA

THURSDAY, Dec. 15, 2016 (HealthDay News) — Specific bacteria may help explain the connection between periodontal disease and rheumatoid arthritis, according to a study published online Dec. 14 in Science Translational Medicine.

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Endometrial Microbiota May Be Linked to Success of IVF

THURSDAY, Dec. 15, 2016 (HealthDay News) — The presence of a non-Lactobacillus-dominated microbiota in a receptive endometrium is associated with poor reproductive outcomes for women undergoing in vitro fertilization (IVF), according to a study published in the December issue of the American Journal of Obstetrics & Gynecology.

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ASS1 Loss Identified in Invasive Bladder Cancer

THURSDAY, Dec. 15, 2016 (HealthDay News) — Loss of argininosuccinate synthetase 1 (ASS1), a key enzyme for arginine synthesis, occurs in invasive bladder cancer, according to a study published online Dec. 12 in The American Journal of Pathology.

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Zika-Related Birth Defects More Extensive Than Thought

THURSDAY, Dec. 15, 2016 (HealthDay News) — Zika’s ability to damage the infant brain may be even more far-reaching and insidious than previously thought, two new studies suggest.

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Triple-Negative Breast Cancer Subtype Chemosensitive

WEDNESDAY, Dec. 14, 2016 (HealthDay News) — For patients with triple-negative breast cancer (TNBC), a BRCA-deficiency (BRCA-D) subtype is chemosensitive, according to a study published online Dec. 13 in PLOS Medicine.

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Universal Group B Streptococci Screening Not Cost-Effective

TUESDAY, Dec. 13, 2016 (HealthDay News) — For women with a singleton pregnancy planning a repeat cesarean delivery, universal group B streptococci (GBS) screening is not cost-effective, according to a study published in the January issue of Obstetrics & Gynecology.

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Methylation of PITX2 DNA Feasible in Prostate Biopsies

TUESDAY, Dec. 13, 2016 (HealthDay News) — For patients with prostate cancer (PCa), methylation of the paired-like homeodomain transcription factor 2 (PITX2) gene is feasible for individualized risk assessment in prostate core biopsies before surgery, according to a study published online Dec. 8 in the Journal of Molecular Diagnostics.

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Effect of Statins on Alzheimer’s May Depend on Gender, Race

MONDAY, Dec. 12, 2016 (HealthDay News) — Effectiveness of statin use in Alzheimer’s prevention may depend on the specific statin, and the gender and race or ethnicity of the patient, according to a study published online Dec. 12 in JAMA Neurology.

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Drones Deemed Safe for Blood Transportation

MONDAY, Dec. 12, 2016 (HealthDay News) — Blood products don’t seem to suffer damage when transported by drones, according to a study published online Nov. 11 in Transfusion.

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CDC: Colombia Sees Increase in Zika-Related Microcephaly

MONDAY, Dec. 12, 2016 (HealthDay News) — Colombia is now experiencing a sharp increase in cases of infant microcephaly, according to research published in the Dec. 9 early-release issue of the U.S. Centers for Disease Control and Prevention’s Morbidity and Mortality Weekly Report.

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Duration of Estrogen Rx May Be Important Factor in Renal Health

MONDAY, Dec. 12, 2016 (HealthDay News) — For midlife ovariectomized Long Evans rats, long-term estradiol (E2) treatment exerts detrimental effects on kidney health, despite lowering blood pressure, while short-term E2 lowers blood pressure and reduces renal damage, according to an experimental study published online Nov. 9 in American Journal of Physiology-Renal Physiology.

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Prevalence of Anti-TSH Receptor Antibody High in Fibromyalgia

MONDAY, Dec. 12, 2016 (HealthDay News) — Patients with fibromyalgia syndrome (FMS) have high prevalence of anti-thyroid-stimulating hormone (TSH) receptor antibody (TRAb), according to a study published online Nov. 30 in the International Journal of Rheumatic Diseases.

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Fecal Microbiota Transplant Cost-Effective for Preventing CDI

MONDAY, Dec. 12, 2016 (HealthDay News) — Use of fecal microbiota transplantation (FMT) is cost-effective for recurrent Clostridium difficile infection (CDI), according to a study published in the December issue of the Journal of Gastroenterology and Hepatology.

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Age-Adjusted Mortality Rate Up From 2014 to 2015 in U.S.

FRIDAY, Dec. 9, 2016 (HealthDay News) — There was an increase in the age-adjusted death rate from 2014 to 2015, and a decrease in life expectancy, according to a December data brief published by the U.S. Centers for Disease Control and Prevention’s National Center for Health Statistics (NCHS).

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Cytotoxic T-Cells Can Induce Metastatic CRC Regression

FRIDAY, Dec. 9, 2016 (HealthDay News) — Administration of cytotoxic T-cells targeting mutant KRAS G12D can induce tumor regression in metastatic colorectal cancer, according to a case report published in the Dec. 8 issue of the New England Journal of Medicine.

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Screening Cuts Transfusion-Transmitted Babesiosis Risk

FRIDAY, Dec. 9, 2016 (HealthDay News) — Screening for Babesia microti antibodies and DNA in blood-donation samples is associated with a reduction in the risk of transfusion-transmitted babesiosis, according to a study published in the Dec. 8 issue of the New England Journal of Medicine.

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Personalized Vaccine Effective Against Acute Myeloid Leukemia

THURSDAY, Dec. 8, 2016 (HealthDay News) — A vaccine made from patient-derived acute myeloid leukemia cells and dendritic cells can dramatically increase the chance of long-term survival against acute myeloid leukemia, according to research published in the Dec. 7 issue of Science Translational Medicine.

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Frequency of Multiple Molecular Diagnoses About 5 Percent

THURSDAY, Dec. 8, 2016 (HealthDay News) — About 5 percent of patients for whom whole-exome sequencing is informative have multiple molecular diagnoses, according to research published online Dec. 7 in the New England Journal of Medicine.

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Higher NT-proBNP Tied to Lower Brain Volume in Older Adults

THURSDAY, Dec. 8, 2016 (HealthDay News) — For older adults without dementia, higher N-terminal pro-B-type natriuretic peptide (NT-proBNP) is associated with lower total brain volume, according to a study published online Dec. 7 in Radiology.

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Prevalence of Disability 2.7 Percent at U.S. Medical Schools

WEDNESDAY, Dec. 7, 2016 (HealthDay News) — The prevalence of disability is 2.7 percent among medical students at U.S. allopathic medical schools, according to a research letter published in the Dec. 6 issue of the Journal of the American Medical Association, a theme issue of medical education.

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Learning Interventions Can Improve Med Student Well-Being

WEDNESDAY, Dec. 7, 2016 (HealthDay News) — Specific learning interventions may improve emotional well-being among medical students, according to a review published in the Dec. 6 issue of the Journal of the American Medical Association, a theme issue on medical education.

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Urine Haptoglobin Can Predict Kidney Damage in T2DM

WEDNESDAY, Dec. 7, 2016 (HealthDay News) — Urine haptoglobin is a novel biomarker for predicting kidney damage in patients with type 2 diabetes (T2D), according to a study published online Nov. 30 in Diabetes Care.

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Number of Cancer Cases, Deaths Up Globally

WEDNESDAY, Dec. 7, 2016 (HealthDay News) — Cancer cases rose 33 percent worldwide in the past 10 years, according to a report published online Dec. 3 in JAMA Oncology.

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State-Specific Variation in Asthma Rates Among Employed Adults

TUESDAY, Dec. 6, 2016 (HealthDay News) — There is state-specific variation in the prevalence of current asthma among employed adults, which depends on industry and occupation, according to a study published online Dec. 2 in Morbidity and Mortality Weekly Report.

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Depression, Suicide Ideation Prevalent in Medical Students

TUESDAY, Dec. 6, 2016 (HealthDay News) — The prevalences of depression or depressive symptoms and suicide ideation are 27.2 and 11.1 percent, respectively, among medical students, according to a review published in the Dec. 6 issue of the Journal of the American Medical Association, a theme issue on medical education.

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HPV16 DNA From Fine-Needle Aspirations OK for Diagnosis

TUESDAY, Dec. 6, 2016 (HealthDay News) — HPV16 DNA detected in fine-needle aspirations from neck masses is a reliable indicator for diagnosis of an HPV-positive oropharyngeal squamous cell carcinoma (SCC), according to a study published Nov. 29 in Head & Neck.

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Colonic Diverticular Disease May Increase Dementia Risk

TUESDAY, Dec. 6, 2016 (HealthDay News) — Patients with colonic diverticular disease may be at an increased risk for dementia, according to a study published Nov. 23 in the Journal of Gastroenterology and Hepatology.

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DASH Diet Reduces Serum Uric Acid in Prehypertension

MONDAY, Dec. 5, 2016 (HealthDay News) — Among adults with prehypertension or stage I hypertension, following the Dietary Approaches to Stop Hypertension (DASH) diet lowers serum uric acid (UA), according to a study published online Nov. 28 in Arthritis & Rheumatology.

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Multimodal Breast Cancer Tx May Up Cytokines, Comorbidities

MONDAY, Dec. 5, 2016 (HealthDay News) — Breast cancer survivors who undergo multimodal treatment have higher cytokines and comorbidities than controls without cancer, according to a study published online Nov. 28 in the Journal of Clinical Oncology.

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Review: Methodological Limitations for OSCC Biomarkers

MONDAY, Dec. 5, 2016 (HealthDay News) — Methodological concerns have limited the analysis of saliva-based biomarkers for oral squamous cell carcinoma (OSCC), according to a review published online Nov. 29 in Head and Neck.

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Functionally ID’d Variants in HNF1A Linked to Diabetes Risk

MONDAY, Dec. 5, 2016 (HealthDay News) — Functionally characterized variants in hepatocyte nuclear factor-1a (HNF1A) genes, which are associated with maturity-onset diabetes of the young (MODY3), are strongly associated with diabetes, according to a study published online Nov. 29 in Diabetes.

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CSF RT-QuIC Has High Diagnostic Specificity, Sensitivity for Prions

FRIDAY, Dec. 2, 2016 (HealthDay News) — Cerebrospinal fluid (CSF) real-time quaking-induced conversion (RT-QuIC) has high diagnostic specificity and sensitivity for prion diseases, according to a study published online Nov. 28 in the Annals of Neurology.

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Alcohol Intake Linked to Increase in Risk of Melanoma

FRIDAY, Dec. 2, 2016 (HealthDay News) — Alcohol intake is associated with increased risk of melanoma, especially in relatively ultraviolet (UV)-spared areas, according to a study published in the December issue of Cancer, Epidemiology, Biomarkers & Prevention.

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Similar Effects for PCSK9, HMGCR Variant-Mediated Lower LDL

FRIDAY, Dec. 2, 2016 (HealthDay News) — Variants in genes encoding proprotein convertase subtilisin-kexin type 9 (PCSK9) and 3-hydroxy-3-methylglutarylcoenzyme A reductase (HMGCR) are associated with almost equivalent effects on the risk of cardiovascular events and diabetes per unit decrease in low-density lipoprotein (LDL) cholesterol level, according to a study published in the Dec. 1 issue of the New England Journal of Medicine.

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More HIV Patients Exhibiting Multidrug Resistance

THURSDAY, Dec. 1, 2016 (HealthDay News) — A significant number of patients with HIV have strains of the virus that are resistant to both older and newer drugs, according to research published online Nov. 30 in The Lancet Infectious Diseases.

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CDC: Fewer U.S. Families Struggling to Pay Medical Bills

THURSDAY, Dec. 1, 2016 (HealthDay News) — The number of people in families having problems paying medical bills fell by nearly 13 million from 2011 through the first six months of 2016, according to a report published by the U.S. Centers for Disease Control and Prevention’s National Center for Health Statistics (NCHS).

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PCPs Order More Food Allergen Panels Than Allergists

THURSDAY, Dec. 1, 2016 (HealthDay News) — Primary care providers (PCPs) order significantly more food allergen panels and generate higher costs per patient than allergists, according to a review published online Nov. 30 in Pediatrics.

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Newborn Screen IDs Previously Unknown Cause of SCID

THURSDAY, Dec. 1, 2016 (HealthDay News) — Mutant BCL11B has been identified as a cause of severe combined immunodeficiency (SCID) in newborn screening, according to a study published in the Dec. 1 issue of the New England Journal of Medicine.

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Dapivirine Vaginal Ring Can Help Prevent HIV-1 Infection

THURSDAY, Dec. 1, 2016 (HealthDay News) — Use of a vaginal ring containing dapivirine is efficacious for prevention of HIV-1 infection, according to a study published in the Dec. 1 issue of the New England Journal of Medicine.

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