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Home 2020 April

Monthly Archives: April 2020

For patients with advanced BRAFV600E/K melanoma

PFS Prolonged With Continuous Dabrafenib, Trametinib in Melanoma

Median PFS longer with continuous versus intermittent treatment, but overall survival similar
Vitamin D deficiency is associated with reduced overall survival for patients with multiple myeloma

Low Vitamin D May Reduce Survival for Some With Multiple Myeloma

Differential effect seen by race, with significantly lower OS for white but not African-American patients
Universal severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) testing of pregnant women presenting for delivery in New York City revealed that most positive patients were asymptomatic

Most SARS-CoV-2-Positive Pregnant Women Asymptomatic at Screening

87.9 percent of the 33 patients who were positive for SARS-CoV-2 were asymptomatic on admission
While health experts continued to call for a national strategy to test more Americans for coronavirus

National Coronavirus Testing Strategy Announced as U.S. Cases Top 1 Million

And, potential vaccine against COVID-19 shows promise, could begin human testing within a few weeks
Abdominal pain

Rare, Serious Illness May Occur in Children With COVID-19

British health officials warn of toxic shock syndrome features, atypical Kawasaki disease in kids with COVID-19
Climate change continues to make air pollution worse

Nearly Half of U.S. Population Breathes Unhealthy Air

More cities saw increase in days with spikes in particle pollution for 2016-2018 versus 2015-2017
Persons aged 60 to 69 years with COVID-19 are the most commonly hospitalized

Patients Aged 60 to 69 Most Often Hospitalized With COVID-19

At California KPNC hospitals, most common age group hospitalized, admitted to ICU was those aged 60 to 69 years
High-dosage chloroquine diphosphate has potential safety hazards when used as adjunctive therapy for patients hospitalized with severe COVID-19

Adding High-Dose Chloroquine Not Advised for Severe COVID-19

High-dose versus low-dose group had higher lethality until day 13, more instances of QTc interval >500 ms
COVID-19 is associated with a high rate of pulmonary embolism

High Rate of Pulmonary Embolism Found for Patients With COVID-19

Two studies demonstrate high rate of PE; 100 percent sensitivity for PE seen for D-dimer level > 2,660 µg/L
An estimated 45.4 percent of U.S. adults may have an increased risk for COVID-19 complications due to chronic conditions

45.4 Percent of U.S. Adults at Risk for Complications With COVID-19

These adults may be at increased risk due to existing chronic conditions including CVD, diabetes, HTN