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Monthly Archives: September 2018

More experienced surgeons are more confident in their assessments of perceived futility

Surgeon Experience Aids Assessment of Futility

Greater experience helps surgeons guide patients, families away from interventions perceived as futile
Once low rheumatoid arthritis disease activity is achieved with tocilizumab plus methotrexate

Combo Therapy Not Needed If Low RA Disease Activity Achieved

Dropping methotrexate, continuing tocilizumab does not lead to worsening of disease activity
Neonates with congenital heart disease have enlarged kidneys on average

Enlarged Kidneys in Neonates With Congenital Heart Disease

Kidneys of neonates with left heart obstruction consistently found to be larger than normal
Diet is an important component that impacts cardiovascular risk

Policies Should Encourage Healthy Food Consumption

Aim should be to prevent CVD with environment where healthy foods are accessible, desirable
Pod mods, which are small

High Nicotine Concentrations Delivered by ‘Pod Mods’

Small devices deliver addictive nicotine dose without noxious taste; pose danger to adolescents
A major non-profit advocacy group is asking that a large government trial comparing treatments for sepsis be shut down.

Critics Demand Stop to ‘Guinea Pig’ Sepsis Clinical Trial

Clovers trial seeks to determine which IV fluids, vasopressors combo works best to curb sepsis
Following an educational intervention

Education Can Up Emotional Intelligence in Residents

Increase in total EI median scores, stress management composite score after intervention
Among individuals undergoing hereditary cancer testing

Cancer-Related Gene Variations Frequently Reclassified

24.9 percent of variants of uncertain significance were reclassified at a single commercial laboratory
The cumulative incidence of appendicitis recurrence within five years is 39.1 percent among patients with uncomplicated acute appendicitis initially treated with antibiotics

Initial Abx Feasible Alternative for Uncomplicated Appendicitis

At five years, cumulative incidence of appendicitis recurrence 39.1 percent with antibiotic treatment
The absence of CHD4 in heart cells results in inappropriate production of non-cardiac muscle proteins

Lack of CHD4 Leads to Abnormal Myofibrils, Heart Defects

Mutation results in failed repression of non-cardiac muscle protein production in developing heart cells