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The presence of psoriatic arthritis

Specific Factors Influence First-Line Biologic Rx for Psoriasis

Presence of psoriatic arthritis, weight, employment status, baseline disease severity all affect selection
For patients receiving direct oral anticoagulant agents for non-valvular atrial fibrillation

Lower Risk of Gastrointestinal Bleeding for Apixaban

In non-valvular a-fib patients, risk of GI bleeding down for apixaban vs. rivaroxaban, dabigatran
For U.S. adults with prediabetes

Prevalence of Metformin Use 0.7 Percent in Prediabetes

Metformin use low even among those with a body mass index of ≥35 kg/m²
In an effort to mitigate the increasing cost of prescription medications

Physicians Finding Ways to Work Around Cost of Rx Medications

One physician devised a workaround for EpiPens, which uses an autoinjector filled with epinephrine
For adolescent girls with polycystic ovary syndrome

ENDO: Rx Intervention Restores Normal Ovulation in PCOS

Low-dose combo of spironolactone-pioglitazone-metformin linked to 2.5-fold higher ovulation rate
Mylan

Mylan Issues Voluntary Recall of Some EpiPen Auto-Injectors

Rare cases of 'failure to activate' spurred the action, company says
Maintenance therapy with cediranib for women with relapsed ovarian cancer is not detrimental to quality of life

Cediranib Tx in Relapsed Ovarian CA Doesn’t Lower Quality of Life

Findings among women on maintenance therapy for relapsed ovarian cancer
The incidence of oxybutynin prescription was 27.3 percent among elderly individuals receiving antimuscarinic prescriptions from 2006 to 2012

Oxybutynin Frequently Used for Overactive Bladder in U.S. Elderly

Despite known adverse effects, including cognitive decline, oxybutynin most frequently prescribed
From 2010 to 2014 there was an increase in use of diabetes medications

Increased Use of Newer Meds for Diabetic Nephropathy in the U.S.

DDP-4 inhibitors used in 54 percent of visits in last quarter of 2014; ACE inhibitors, ARBs often used
For older men

Suicide Risk Not Up With New Rx of 5α-Reductase Inhibitor for BPH

But increased risk of self-harm and depression during initial 18 months after initiation of 5α-reductase