Advertisement
Home Tags Prescription Drugs

Tag: Prescription Drugs

Adding a sulfonylurea or metformin to insulin is associated with approximately a 1 percent reduction in hemoglobin A1c

Clinical Evidence Synopsis Published for T2DM

Adding sulfonylurea or metformin to insulin decreases HbA1c about 1%
Internal medicine patients are frequently prescribed potentially inappropriate medications (PIMs)

Screening Tools Identify Potentially Inappropriate Meds

However, substantial proportion of PIMS identified in internal medicine ward are not clinically relevant
Oral semaglutide is associated with better glycemic control than placebo among type 2 diabetes patients with insufficient glycemic control

Glycemic Control Up With Oral Semaglutide in Type 2 Diabetes

Phase 3 studies next to assess longer-term/clinical outcomes, safety
High-volume continuous venovenous hemodiafiltration and resin-sorbent hemoperfusion is effective for eliminating metformin

Venovenous Hemodiafiltration Improves Metformin Toxicity

Case report describes treatment of female patient who attempted suicide with metformin overdose
More than one-quarter of college students report believing that nonmedical use of prescription stimulants can improve academic performance

Many College Students Believe Stimulants Can Boost Grades

More frequent use of alcohol, marijuana also tied to increased likelihood of prescription stimulant use
For patients with stage 4 or 5 chronic kidney disease and hepatitis C virus infection

High Sustained Response Rate for Glecaprevir, Pibrentasvir in HCV

12-week therapy results in high rate of sustained virologic response for patients with CKD, hepatitis C
The Multidisciplinary Multistep Medication Review is effective for discontinuation of inappropriate medication among elderly nursing home residents without a decline in their well-being

3MR Intervention Effective for Discontinuing Inappropriate Meds

Multidisciplinary Multistep Medication Review is effective for use in frail nursing home residents
The overall incidence of adverse effects and serious adverse effects is similar in patients with type 2 diabetes mellitus taking dapagliflozin or placebo

Rate of Adverse Effects for Dapagliflozin Similar to Placebo

Although genital infections, renal function AEs found more frequently with dapagliflozin than placebo
Nocebo hyperalgesia is stronger when an inert treatment is labeled as being an expensive medication rather than a cheap one

Stronger Nocebo Effect When Inert Rx Labeled As Expensive

Neural interactions between cortex, brainstem, and spinal cord mediate this effect
Most cancer drugs that enter the market in Europe have no evidence of benefit for survival or quality of life

Most Cancer Drugs Approved in Europe Show No Survival Benefit

Even in the postmarketing period, half of cancers have no evidence of significant survival gain