Tag: Prescription Drugs
Closures of Automotive Assembly Plants Tied to Opioid OD Deaths
Increases in opioid overdose mortality largest for non-Hispanic white men aged 18 to 34, 35 to 65 years
BMI, Survival Linked in NSCLC Treated With Atezolizumab
Overall, progression-free survival improved for patients with high BMI; link strongest with high PD-L1 expression
Tivozanib Bests Sorafenib in Metastatic Renal Cell Carcinoma
Progression-free survival longer in those receiving tivozanib as third- or fourth-line therapy
Gabapentinoids, Opioids Combo Carries Risk for Breathing Problems
Serious breathing problems can occur in patients who use gabapentinoids with opioids or other CNS depressants
Anifrolumab Improves Response at 52 Weeks in Lupus
Rate of composite response showing reduced disease activity higher with anifrolumab versus placebo
Misuse of Nonopioid Medications Appears to Be on the Rise in U.S.
Increases seen for misuse/abuse, suicide attempts, and hospitalizations linked to gabapentin, baclofen
Antiretroviral Prescribing in Pregnancy Strays From National Guidelines
Many prescribed ARVs with insufficient evidence, not recommended for use in pregnant women with HIV
Fenfluramine Reduces Convulsive Seizures in Dravet Syndrome
Drop in monthly frequency of convulsive seizures significantly greater with fenfluramine versus placebo
FDA to Allow States to Import Prescription Drugs From Other Countries
All imports would have to be FDA-approved, tested to ensure quality, relabeled to meet U.S. labeling requirements
Addition of Maintenance Olaparib Slows Advanced Ovarian Cancer
Benefit substantial for homologous-recombination deficiency positive tumors with, without BRCA mutations
