Advertisement
Home Tags Osteoporosis

Tag: Osteoporosis

In patients who have previously suffered a vertebral fracture

Longer Bisphosphonate Drug Holiday May Up Fracture Risk

For those with previous vertebral fracture, major osteoporotic fractures increased with holidays >12 months
A second bone mineral density (BMD) assessment about three years after initial measurement does not improve discrimination beyond baseline BMD value alone for women who do and do not experience subsequent hip fracture or major osteoporotic fracture

Second BMD Measurement Not Beneficial for Identifying Hip Fracture

Second BMD assessment about three years after initial measure not linked to improved discrimination
Inhibition of sclerostin with romosozumab may increase cardiovascular risk

Inhibition of Sclerostin May Increase Cardiovascular Risk

SOST genetic variants linked to lower risk for fracture and osteoporosis but higher risk for MI, major CV AEs
In a joint guidance document issued by the American Society for Bone and Mineral Research

Guidance Issued for Osteoporosis Management During COVID-19

Alternative methods for parenteral treatments include off-site clinics, home visit, self-injection
In a joint guidance document issued by the American Society for Bone and Mineral Research

Guidance Issued for Osteoporosis Management During COVID-19

Alternative methods for parenteral treatments include off-site clinics, home visit, self-injection
Social factors might be significant contributors to coexisting metabolic syndrome and osteoporosis in postmenopausal women

Social Inequality May Contribute to Poor Metabolic, Bone Health

Risk for coexisting metabolic syndrome, osteoporosis up for postmenopausal women with low social status
While low blood levels of vitamin D are associated with osteoporotic fractures

Alone, Low Vitamin D Does Not Cause Osteoporotic Fractures

Mendelian randomization analysis reveals no causal link between low vitamin D and fractures
In an Endocrine Society guideline update

Romosozumab Added to Guideline for Management of Osteoporosis

Drug recommended for postmenopausal women at very high fracture risk but not at high risk for heart disease, stroke
Supplementation with vitamin D alone does not appear to reduce the risk for fracture

Vitamin D Supplementation Alone May Not Reduce Fracture Risk

However, meta-analysis shows significant reduction in any, hip fracture with vitamin D plus calcium
Patients with atopic eczema have an increased risk for fracture

Fracture Risk Increased in Adults With Atopic Eczema

Fracture risk up with increasing eczema severity, with strongest associations for spinal, pelvic, hip fracture