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OxyContin maker Purdue Pharma has reached a tentative settlement with a coalition of states and local governments that sued the company over its role in America's ongoing opioid crisis

Purdue Pharma Tentatively Reaches Settlement in Opioid Lawsuits

Deal is said to be worth $10 billion to $12 billion; company will not admit to wrongdoing
Patients with hidradenitis suppurativa have an increased risk for long-term opioid use

Risk for Long-Term Opioid Use Up in Hidradenitis Suppurativa

Odds higher for HS patients with advancing age, ever smoking, history of depression, comorbidity
Settlement talks with OxyContin maker Purdue Pharma over its role in the U.S. opioid crisis have reached a stalemate and the company is expected to file for bankruptcy

Opioid Maker Purdue Pharma Expected to File for Bankruptcy

Settlement talks over Purdue's responsibility for the nation's opioid crisis have stalled
Use of the widely prescribed opioid tramadol is associated with a greater risk for developing hypoglycemia compared with almost every other opioid

Use of Pain Reliever Tramadol May Up Risk for Hypoglycemia

Retrospective analysis of adverse events reported to FDA shows risk similar to that seen with methadone
Nearly $2 billion in grants to help fight the U.S. opioid epidemic will be handed out to states and local governments

White House Announces Nearly $2 Billion in Grants to Fight Opioid Epidemic

SAMHSA will provide $932 million to every state, some U.S. territories for treatment, recovery programs
The enhanced recovery after surgery program

Cesarean Section Quality Initiative Cuts Opioid Use

Preoperative and postoperative process changes lead to faster recovery without increased pain
Opioid deaths decreased during January to July 2018

CDC: January to July 2018 Saw Decrease in Opioid Deaths

But deaths from illicitly manufactured fentanyl increased during same period
Exposure to opioid maintenance treatment in the womb does not seem to cause additional harm to newborns

Prenatal Exposure to OMT Does Not Worsen Neonatal Outcomes

Growth parameters similar to those for newborns of women with opioid use disorders during pregnancy
Purdue Pharma

OxyContin Maker Offers Up to $12 Billion to Settle Opioid Claims

Potential deal has been discussed by lawyers representing Purdue and at least 10 state attorneys general
An Oklahoma judge on Monday ruled against one of America's biggest companies

Oklahoma Judge Fines Johnson & Johnson $572 Million Over Opioid Drug Crisis

Verdict could have huge implications as other states and communities target pharmaceutical firms