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Tag: Multiple Sclerosis

Early Treatment of Demyelination Events Cuts Long-Term Disability in MS

Reduced risk for reaching EDSS 3.0, secondary progressive MS, sustained disease progression seen with very early treatment

Genes Identified in Association With Multiple Sclerosis Severity

Significant association identified with rs10191329 in the DYSF-ZNF638 locus, with risk allele shortening time to needing walking aid

Pro-Inflammatory Diet Linked to Worsening Relapse Rate in MS

Association seen between energy adjusted dietary inflammatory index score and fluid-attenuated inversion recovery lesion volume

Rituximab Not Noninferior to Ocrelizumab for Relapsing-Remitting MS

Cumulative hazard of relapses higher among patients treated with rituximab versus ocrelizumab

Whites Have Highest Prevalence of Multiple Sclerosis in the United States

Highest prevalence seen in those aged 45 to 64 years; prevalence also increased with each degree of latitude

AAN: Teriflunomide Reduces Clinical Events in Radiologically Isolated Syndrome

Significant reduction seen in clinical events with teriflunomide; nonsignificant reduction noted in Gd+ lesions, new or enlarging T2 lesions

Sleep Disorders Contribute to Cognitive Decline in Multiple Sclerosis

Insomnia, sleep apnea explain roughly 10 to 34 percent of the relationship between multiple sclerosis and cognitive dysfunction

MS Relapse Rate Not Increased After Fertility Treatments

Mean annualized relapse rate not different before versus after controlled ovarian stimulation

AAN: Mediterranean Diet Score Linked to Cognition in MS

Higher MEDAS score independently predicted lower risk for cognitive impairment; link stronger for those with progressive disease

Evidence Found of Causal Link for Multisite Chronic Pain and MS, RA

Association with multiple sclerosis and rheumatoid arthritis may be partially mediated by body mass index