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Tag: Herpes Simplex (Genital)

There is a need for development of new anti-herpetic compounds with different mechanisms of action for herpes simplex viral keratitis

Treatment Options Reviewed for Herpes Simplex Viral Keratitis

Options include acyclovir, valacyclovir, topical ganciclovir; need for development of new compounds
For older women

Herpes Simplex Virus Linked to Frailty, Mortality

Only HSV-2 independently predicts five-year mortality risk in older women aged 70 to 79 years
In a letter to the editor published online March 24 in Clinical & Experimental Ophthalmology

Reactivation of HSV Described in Patient After Cataract Surgery

Herpes simplex uveitis ID'd as cause of persistently elevated intraocular pressure after cataract sx
Activation of c-Jun N-terminal kinase is essential for herpes simplex virus gene expression during virus reactivation from latent neuronal infection

c-Jun N-terminal Kinase Essential for HSV Reactivation

JNK signaling results in histone methyl-phospho switch on HSV lytic promoters
Pericoital application of tenofovir gel may substantially cut women's risk of contracting herpes simplex virus type 2

Tenofovir Gel Could Help Prevent Genital Herpes Simplex

Pericoital application of tenofovir gel linked to reduced risk of HSV-2 infection
Unique presentation of herpes simplex virus infection in pregnancy can be misdiagnosed as premature rupture of membranes

Herpes Simplex Virus Can Mimic Premature Rupture of Membranes

Case vignette describes woman with leakage of clear fluid, despite normal amniotic fluid volume
A genetically engineered form of the herpes virus is showing promise in slowing the progression of melanoma

HSV-Derived Immunotherapy Promising in Advanced Melanoma

Study shows it helped a minority of patients, and experts say this approach has promise
The prodrug valacyclovir reduces viral load in HIV-1 infected herpes simplex virus-2-seronegative patients

Valacyclovir Cuts Viral Load in HIV-1+/HSV-2 Seronegative

Prodrug valacyclovir active in HIV-1 infected patients who are HSV-2 seronegative
A new study in mice hints at the success of a vaccine against the herpes simplex virus. The research was published online March 9 in eLife.

HSV-2 Vaccine Shows Promise in Experimental Research

Study in mice hints at the success of a vaccine against the virus