Advertisement
Home Tags Genetics

Tag: Genetics

Two single nucleotide polymorphisms have been identified which confer differential benefit for aspirin and/or nonsteroidal anti-inflammatory drug use in relation to colorectal cancer risk

Genetic Variation Impacts Aspirin/NSAID Link to CRC Risk

Use of aspirin, NSAIDs lowers risk of CRC in association with genetic variation at two SNPs
For patients with early-onset colorectal cancer

Frequency of Germline TP53 Mutations ID’d in Early-Onset CRC

Germline mutations detected at a frequency of 1.3 percent in patients with early-onset colorectal cancer
A majority of Americans taking part in a new poll said they'd be interested in genetic testing to see if they or their children are at risk for serious illnesses. The findings were published online March 6 in Public Health Genomics.

Poll: Majority of Americans Interested in Genetic Testing

But researchers wonder if everyone is adept at accurately interpreting test results
Ubiquinone (UQ) does not act as an antioxidant in vivo

Study Explores In Vivo Role of Ubiquinone in Mouse Model

Partial restoration of UQ levels, mitochondrial function can reverse disease phenotypes
Neither circulating 25-hydroxyvitamin D levels nor common variations in vitamin D pathway genes appear to be associated with risk of fatal prostate cancer

No Link Found Between Vitamin D Level and Fatal Prostate Cancer

Also, no significant associations found between vitamin D-related SNPs and fatal prostate cancer
A family history of prostate cancer may be tied to a woman's risk of breast cancer

Family Hx of Prostate CA May Increase Risk of Breast CA Too

Doctors should ask about medical history of first-degree male relatives, researchers say
Use of localized correlated spectroscopy shows significant changes in women with BRCA1 and BRCA2 mutations

Correlated Spectroscopy IDs Changes in BRCA1/2 Carriers

Lipid and metabolite deregulation seen in breast tissue of women carrying BRCA1/2 mutations
For patients with non-small-cell lung cancer with epidermal growth factor receptor mutations

L858R Mutation in Circulating Free DNA Is Prognostic in NSCLC

L858R mutation in tumor tissue or cfDNA is marker of shorter overall, progression-free survival
For many people

Genetic Mutations Found in Leukemia Rise With Age

But just having cancer-linked DNA doesn't mean the disease will develop, study authors stress
A single-nucleotide polymorphism in the promoter region of the CEP72 gene

SNP Linked to Vincristine-Related Neuropathy in ALL

SNP in promoter region of CEP72 gene linked to risk and severity of neuropathy in children with ALL