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Researchers have identified immune genes that may affect mortality in patients with glioblastoma multiforme

Eight Immune Genes Identified As Playing a Role in Glioblastoma

Discovery might eventually lead to better treatment for glioblastoma multiforme
Genetic analysis can improve diagnosis and management of intellectual developmental disorder and unexplained metabolic abnormalities

Genetic Analysis Offers Options for Some Developmental Delay

Exome sequencing led to better treatments in four of 10 cases studied
Women who carry common gene variants linked to breast cancer can still reduce risk of the disease by following a healthy lifestyle

Genetic Breast Cancer Risk Can Be Mediated by Healthy Lifestyle

Key lifestyle factors include maintaining a healthy weight, not smoking, limiting alcohol, no HRT
Average leucocyte telomere length and the abundance of short telomeres (percent LTL <3 kb) are not significant independent determinants of subclinical atherosclerosis

Telomere Length Not Significantly Associated With Atherosclerosis

LTL, abundance of short telomeres are not independent determinants of atherosclerosis
Men who experience the loss of chromosome Y from their blood cells as they age may have an increased risk of developing Alzheimer's disease

Loss of Y Chromosome in Blood Tied to Alzheimer’s Risk in Men

The greater the Y chromosome loss, the higher the risk of developing Alzheimer's, researchers say
In patients with telomere diseases

Danazol Treatment Linked to Telomere Elongation

Reduction in rate of telomere attrition at 24 months; gain in telomere length seen from six months
Precision cancer treatment that's guided by genetic clues from the patient's own tumor appears to improve outcomes

ASCO: Phase I Cancer Drug Trials Benefit From Precision Medicine

Better outcomes for patients whose treatment is selected based on molecular characteristics of tumor
Skeletal muscle TRIB3 mediates glucose-induced insulin resistance in a mouse model of diabetes

Skeletal Muscle TRIB3 Mediates Diet-Induced Insulin Resistance

TRIB3 overexpressing mice have greater weight gain, worse insulin resistance in response to high-fat diet
ASGR1 mutation carriers have reduced levels of non-high-density lipoprotein cholesterol and reduced risk of coronary artery disease

ASGR1 Mutation Linked to Reduced Levels of Non-HDL-C

Heterozygous mutation carriers have lower levels of non-HDL-C, reduced risk of coronary artery disease
Neuronal growth hormone secretagogue receptor is involved in regulating energy metabolism

Neuronal GHS-R Involved in Regulating Energy Metabolism

Deletion of neuronal Ghsr in mice almost completely prevents diet-induced obesity