Tag: DNA-
Early Diagnosis of High-Grade Serous Ovarian Cancer Feasible
Copy number profile abnormality values of DNA extracted from Pap samples higher from pre-HGSOC than healthy women
Concurrent RNA and DNA Sequencing Improves Variant Detection
Overall, 17.1 percent of 545 pathogenic/likely pathogenic splicing variants were dependent on RNA evidence for classification
Sample-to-Answer, Point-of-Care HPV DNA Test Feasible
Test requires six user steps and gives answer in 45 minutes
Protocol Examined for Returning Results in Genomic Research
Among participants in a biobank found to be carrying pathogenic or likely pathogenic variants, 76.3 percent unaware of these research results
Blood Biomarker May Detect Acute Heart Transplant Rejection
Blood test measuring percent donor-derived cell-free DNA could eliminate much of the need for endomyocardial biopsy
Methylation Analysis of cfDNA IDs >50 Cancer Types
Sensitivity increased with increasing stage from 39 percent in stage I to 92 percent in stage IV
Low-Dose Chest CT Does Not Seem to Alter Chromosomal DNA
Increase in number of double-strand breaks, chromosomal aberrations seen with standard-dose CT
Fragmentation Profiles of Cell-Free DNA Can Detect Cancer
Combined with mutation-based cell-free DNA analyses, 91 percent of cancer patients identified
Plasma Marker Predicts Allograft Failure in Lung Transplant
Average donor-derived cell-free DNA in highest tertile linked to increased risk for allograft failure
Review Addresses Cell-Free DNA Sequencing in Pregnancy
cfDNA testing for trisomy 21, 18, 13 recommended in pregnancy; no FDA oversight for testing
