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Esketamine seems to be efficacious and safe for patients with treatment-resistant depression

Esketamine Safe, Effective for Treatment-Resistant Depression

Change in Montgomery-Åsberg Depression Rating Scale score superior for esketamine versus placebo
Girls with menarche at earlier ages may be at elevated risk for mental health issues in adolescence that carry into adult years

Early Menarche May Affect Mental Health in Adulthood

Increased risk of depression, antisocial behaviors in adolescence may carry into adulthood
Parkinson's disease patients with depression have impaired white matter integrity

Impaired White Matter Integrity for Depression in Parkinson’s

Reduced fractional anisotropy values in left anterior corona radiata, left cingulum of depressed patients
Adolescents with depression who are poor responders to treatment do not have more densely connected networks

Network Density Not Linked to Response in Teen Depression

No significant association between higher network strength and poorer outcomes
Women at both extremes of the weight spectrum have low mean serum allopregnanolone

Mean Serum Allopregnanolone Low Across Weight Extremes

Also tied to increased depression and anxiety severity, independent of body mass index
Heart rate variability and specific inflammatory biomarkers can differentiate major depressive disorder from depression in bipolar disorder

Simple ECG May Help Distinguish MDD From Bipolar Depression

Higher low-frequency heart rate variability, lower levels of IL-10 and MCP-1 for major depression
For youths with depression

Treatment Trajectories Vary for Children With Depression

Most common class got psychotherapy monotherapy, and had lowest incidence of attempted suicide
For patients with depression and anxiety

Online CBT Program Beneficial for Depression, Anxiety

But adding internet support group doesn't further improve mental health-related QoL, mood, anxiety
Sertraline treatment does not significantly improve depressive symptoms among patients with non-dialysis-dependent chronic kidney disease and major depressive disorder

Sertraline Treatment No Benefit for Depressive Symptoms in CKD

No improvement for patients with MDD and chronic kidney disease without dialysis dependence

The American Society of Reproductive Medicine, Oct. 28- Nov. 1

The 73rd Annual Meeting of the American Society for Reproductive Medicine (ASRM) The annual meeting of the American Society for Reproductive...