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Tag: Crohn’s Disease

Upadacitinib Superior to Placebo in Moderate-to-Severe Crohn Disease

Superior response seen with upadacitinib induction and maintenance treatments

FDA Approves First Pill to Treat Moderate-to-Severe Crohn Disease

In clinical trials, more patients taking Rinvoq achieved remission and reduced intestinal inflammation compared with patients given a placebo

Small Increase in Lymphoma Risk Seen With Crohn Disease, Ulcerative Colitis

Hazard ratios highest for patients exposed to immunomodulators and biologics or second-line biologics

Adalimumab + Methotrexate Beneficial for Pediatric Crohn Disease

Reduction in treatment failure seen for adalimumab, but not infliximab, initiators treated with methotrexate combination therapy

Genetic, Lifestyle Factors Independently Linked to IBD Risk

For those with high genetic risk, hazard ratios were reduced nearly by half for favorable lifestyle versus unfavorable lifestyle

Perianal Disease, Stricturing or Penetrating Behavior Tied to Crohn Disease Outcomes

Findings in Brazil similar to those in countries with a high prevalence of Crohn disease

Lifestyle Modification Can Reduce Proportion of IBD Burden

A considerable proportion of ulcerative colitis, Crohn disease cases could be prevented by adherence to low modifiable risk score, healthy lifestyle

About Half of Patients With IBD Have Zinc Deficiency

Overall mean zinc deficiency prevalence 54 percent in Crohn disease and 41 percent in ulcerative colitis

C-Section Linked to Increased Risk for Crohn Disease in Offspring

No association seen between mode of delivery and other gastrointestinal disorders later in life among offspring

Diagnostic Accuracy of MRE Indices Studied for Active Crohn Disease

High sensitivity, but low specificity, seen for sMARIA, London, 'extended' London scores for active terminal ileal Crohn disease