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Tag: Cancer: Colon

The combination pill Lonsurf (trifluridine and tipiracil) has been approved by the U.S. Food and Drug Administration to treat metastatic colorectal cancer in patients who aren't responding to other treatments

FDA Approves Lonsurf for Metastatic Colorectal Cancer

For patients with metastatic CRC previously treated with chemotherapy, biological therapy
Given its high cost

Regorafenib Deemed Not Cost-Effective for Metastatic CRC

Findings based on its use as third-line treatment of metastatic colorectal cancer
Electronic health record-based triggers may cut time to diagnostic evaluation of colorectal and prostate cancer

EHR Triggers Cut Time to Diagnostic Cancer Evaluation

Findings among veterans flagged for delayed diagnosis of prostate, colorectal cancer
Many patients receive surgical and medical oncology care from different hospitals

Oncology Care Often Received at Multiple Hospitals

More than a third of colon cancer patients in study get care from different facilities
The U.S. Preventive Services Task Force has concluded that the benefits and harms of low-dose aspirin for prevention of cardiovascular disease and cancer vary by patient age. These findings form the basis of a draft recommendation statement published online Sept. 14 by the USPSTF.

USPSTF Recommendations for Aspirin Use Vary by Age

Recommended for some patients aged 50 to 59 years; insufficient evidence for those <50, ≥70
Dual-modality diffuse reflectance spectroscopy-fluorescence spectroscopy can differentiate tumor tissue from surrounding tissue in patients undergoing colorectal cancer resection

Dual-Modality DRS-FS Discerns Tumor From Surrounding Tissue

Diffuse reflectance spectroscopy-fluorescence spectroscopy sensitive, specific in colorectal cancer
A minority of colorectal cancer survivors experience social distress

Social Distress ID’d in Minority of Colorectal Cancer Survivors

Strongest predictor of social distress is having three or more long-term conditions
Regularly taking low-dose aspirin or other nonsteroidal anti-inflammatory drugs may lower long-term risk of colorectal cancer

Low-Dose Aspirin, Other NSAIDs May Lower Colorectal Cancer Risk

Findings for consistent use over 5 or more years
Total coffee intake is associated with colon cancer recurrence and mortality for patients with stage III disease

Drinking Coffee May Cut Risk of Death in Stage III Colon Cancer

Patients consuming ≥4 cups/day of caffeinated coffee have lower recurrence, mortality risk
A scoring system can stratify risk for advanced colorectal neoplasia in asymptomatic adults

Index Stratifies Risk for Advanced Colorectal Neoplasia

Authors suggest scoring system may allow tailoring of screening methods in those at average risk