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Tag: Cancer: Breast

Non-alcoholic fatty liver disease is associated with development of cancer

NAFLD Linked to Increased Cancer Incidence Rate

NAFLD strongly tied to development of hepatocellular carcinoma, CRC in males, breast cancer in females
African-American women with type 2 diabetes appear to be at increased risk of developing estrogen receptor-negative (ER-) breast cancer

ER- Breast CA Risk Up for African-Americans With T2DM

ER- type accounts for increased breast cancer risk in African-American women; highest risk in nonobese
When adjuvant endocrine therapy for estrogen receptor-positive breast cancer is stopped after five years

Breast Cancer Recurrences Steady After Therapy Cessation

Women with ER-positive BC who stop therapy after 5 years have steady recurrence rate up to 20 years
After adoption of the Affordable Care Act

Incidence of Early-Stage Breast CA, CRC Up With ACA Adoption

No change in incidence of locally advanced or metastatic-stage cancer after ACA adoption
PARP inhibitors demonstrate activity in triple-negative breast cancer tumors without BRCA1/2 mutations

PARP Inhibitors Promising Beyond BRCA1/2 Altered Tumors

Talazoparib caused regression in 5 patient-derived xenografts, 4 without germline BRCA1/2 mutations
The combination of elastography and color Doppler ultrasonography with B-mode US in women with dense breasts can increase the positive predictive value of screening and reduce the number of false-positives

Elastography and Color Doppler Improve Breast Ultrasound

Together, the technologies increase predictive value of screening while decreasing unnecessary biopsies
Automated breast ultrasonography may not be of added value to yearly full-field digital mammography and dynamic contrast agent-enhanced magnetic resonance imaging surveillance of carriers of the BRCA mutation

Multimodal Surveillance Regimen May Not Benefit BRCA Carriers

Biannual automated breast ultrasound may not add value to annual mammography, MR imaging
The 70-gene signature assay affects treatment decisions among physicians treating patients identified as being at intermediate risk with the 21-gene assay

70-Gene Signature Impacts Treatment Decisions in Breast CA

70-GS linked to change in treatment decisions for intermediate-risk patients based on 21-gene assay
Swedish massage therapy is associated with clinically significant relief from cancer-related fatigue in breast cancer survivors

Swedish Massage May Reduce Cancer-Related Fatigue

For breast cancer survivors, larger drop in fatigue scores with Swedish massage than light touch
Cryotherapy may be useful for preventing symptoms of chemotherapy-induced peripheral neuropathy

Cryotherapy May Prevent Chemo-Induced Neuropathy

Breast cancer patients on paclitaxel had lower incidence of peripheral neuropathy with cryotherapy