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Tag: Cancer: Bladder

Recovery From Radical Cystectomy Takes Three to Six Months

No difference seen in percentage of patients recovering at each time point for robot-assisted versus open radical cystectomy

Carbogen and Nicotinamide With Radiation Feasible for Bladder Cancer

Trial involving seven patients with locally advanced bladder cancer shows concurrent CON with radiation therapy feasible in Australia

Adjuvant Nivolumab Slows Muscle-Invasive Urothelial Carcinoma

Disease-free survival was longer with adjuvant nivolumab in intention-to-treat population, for those with PD-L1 expression at least 1 percent

Enfortumab Vedotin Prolongs Survival in Advanced Urothelial Cancer

Overall survival longer compared with standard chemo for disease progression following platinum-based chemo and PD-1 or PD-L1 inhibitor

Aspirin Use Tied to Longer Bladder, Breast Cancer Survival

However, aspirin use in older adults not tied to incidence of various cancer types

Smoking is tied to worse bladder cancer outcomes following radical cystectomy

Smoking Tied to Worse Bladder Cancer Outcomes After Surgery

Poor outcomes include lower response rate to chemotherapy, higher mortality, recurrence
Avelumab added to best supportive care prolongs survival for patients with unresectable local advanced or metastatic urothelial cancer

Avelumab Prolongs Survival in Advanced Urothelial Cancer

Findings seen in patients with advanced, metastatic disease that did not progress with first-line chemo
Childhood body mass index is positively associated

High BMI in Childhood May Up Risk for Bladder Cancer as Adult

Height inversely linked to bladder cancer, while excess BMI gain in childhood linked to increased risk
For patients with metastatic urothelial carcinoma

Addition of Atezolizumab May Aid in Metastatic Urothelial Cancer

Phase 3 trial shows prolonged progression-free survival for atezolizumab plus platinum-based chemo
The June 2018 U.S. Food and Drug Administration label restriction on first-line immunotherapy for advanced bladder cancer was associated with a decrease in immunotherapy use and an increase in chemotherapy use

FDA Labeling Restriction Quickly Reflected in Oncology Practice

FDA label change linked to decrease in immunotherapy use, increases in chemotherapy use, PD-L1 testing