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There is an association between orthostatic hypotension and an increased risk for dementia

Orthostatic Hypotension May Increase Risk of Dementia

Sudden blood pressure drops may lead to hypoxia, with detrimental effects on brain tissue
Some antihypertensive medications may increase the risk that patients will be hospitalized for depression and bipolar disorder

Some Antihypertensives Linked to Depression, Bipolar Risk

Research suggests possible differential effects of antihypertensive medications on mood
An increase in systolic blood pressure due to genetic variants is associated with increased risk of type 2 diabetes

Genetic Increase in SBP Linked to Risk of Type 2 Diabetes

1 mm Hg elevation of SBP levels due to genetic score linked to increased risk of type 2 diabetes
Midlife hypertension may increase risk for dementia later in life

Midlife Hypertension Appears Detrimental to Cognitive Function

New statement from American Heart Association warns of link
For adults undergoing surgery

Eight Pre-Op Variables Linked to Post-Op Kidney Function

Factors including low preoperative mean arterial BP tied to increases in eGFR, kidney injury
Systolic blood pressure variability is associated with mortality

Systolic Blood Pressure Variability Linked to Mortality, Morbidity

Increased SBP variability tied to mortality, coronary heart disease, stroke, end-stage renal disease
Engaging Americans at high risk for cardiovascular disease in aggressive efforts to lower their blood pressure could save more than 100

Tighter Systolic BP Control Could Save 100K U.S. Lives Annually

Findings indicate high-risk adults would benefit from intensive program to lower SBP to 120 or less
Nearly five million Medicare prescription drug enrollees aren't taking their antihypertensive medication as directed

Many Medicare Patients Non-Adherent to Antihypertensives

Antihypertensive medication regimens should be made as easy-to-follow as possible
A large randomized trial is being developed to compare the effectiveness of hydrochlorothiazide with chlorthalidone in Veterans Affairs patients

Large Trial Proposed to Compare HCTZ, Chlorthalidone

Researchers plan randomized study to compare hydrochlorothiazide, chlorthalidone
Among adults with a hospitalization

Unstable Vital Signs for About One in Five Hospital Discharges

Presence of one or more instabilities linked to increased risk-adjusted odds of death or readmission