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Tag: ALS (Lou Gehrig’s Disease)

Stakes Are High Ahead of FDA Panel Vote on ALS Drug

AMX0035 is a combination of two established drug ingredients -- sodium phenylbutyrate and taurursodiol

Professional Football Players at Higher Risk for ALS

Risk for incidence, mortality from amyotrophic lateral sclerosis nearly fourfold higher for NFL players compared with the U.S. male population

Lifetime Physical Activity Not Linked to Risk for ALS

Heavy occupational work intensity may increase ALS risk; survival in newly diagnosed ALS patients worse with inactivity, highest activity level

New Gene Variants Identified That May Raise Risk for ALS

Mutations identified in TP73 in ALS patients; mutations caused abnormal differentiation, apoptosis in myoblast differentiation assay

Long-term survival analysis shows that patients with earlier initiation of sodium phenylbutyrate-taurursodiol treatment for amyotrophic lateral sclerosis have longer median overall survival

Investigational Drug May Prolong Survival in Patients With ALS

Median survival 6.5 months longer with initiation of PB-TURSO treatment compared with placebo
For patients with amyotrophic lateral sclerosis

Sodium Phenylbutyrate-Taurursodiol Promising for ALS

Slower functional decline seen with active drug versus placebo through 24 weeks
High body mass index and weight gain are associated with reduced long-term risk for amyotrophic lateral sclerosis

High BMI, Weight Gain Linked to Lasting Decrease in ALS Risk

Link found between high BMI, weight gain and lower risk for amyotrophic lateral sclerosis decades later

American Academy of Neurology, May 4-10

The 71st Annual Meeting of the American Academy of Neurology The annual meeting of the American Academy of Neurology was held from May...
Professional soccer players may have an increased risk for amyotrophic lateral sclerosis

AAN: Professional Soccer Players Show Increased Risk for ALS

Median age of diagnosis 43.3 years in soccer players versus 62.5 years in general population
In 2015

CDC: U.S. Prevalence of ALS Was 5.2 Per 100,000 in 2015

Total of 16,583 cases identified in 2015 using National Amyotrophic Lateral Sclerosis Registry