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Tag: Acne

Tretinoin 0.05 percent lotion (ALTRENO Lotion) provides statistically significant improvement in patients with moderate-to-severe acne compared with placebo

Clinical Trials Support Efficacy of Tretinoin Lotion for Tx of Acne

Phase 3 trials show significant improvement compared with placebo for moderate-to-severe acne vulgaris
Acne is associated with increased probability of developing major depressive disorder

Acne Linked to Increased Risk of Major Depressive Disorder

Significantly increased risk of developing MDD in first five years after diagnosis; highest risk in first year
Microneedling combined with trichloroacetic acid peeling is more effective than microneedling by dermaroller plus platelet-rich plasma or microneedling alone for treatment of acne scarring

Microneedling Plus TCA Peel Performs Well in Acne Scarring

Combo of microneedling + trichloroacetic acid more effective than microneedling +/- platelet-rich plasma
Long-term oral macrolide administration may increase macrolide-resistant Propionibacterium acnes

Long-Term Macrolide Use Linked to Resistant P. Acnes

Long-term oral macrolides for treatment of acne may increase macrolide resistance
Acne patients have higher levels of serum homocysteine

Serum Homocysteine Higher in Acne Patients

Authors say measurement of serum homocysteine may be important for patient management
The combination of sequential 70 percent glycolic acid peel and microneedling results in better acne scar improvement than microneedling alone

Addition of Peel to Microneedling Improves Acne Scar Treatment

Addition of glycolic acid peel to microneedling linked to better scar improvement, skin texture
Barbers can identify pseudofolliculitis barbae and acne keloidalis nuchae and advise patients on management

Most Barbers Can Identify Pseudofolliculitis Barbae

Fewer barbers identify acne keloidalis nuchae; most know razor use will aggravate conditions
For patients with acne

Pulsed Dye Laser Doesn’t Significantly Improve Acne

Patient satisfaction on laser-treated side was 75, 81, and 81 percent at second, fourth, and eighth week
There is insufficient evidence to support delaying several cutaneous surgical procedures in the setting of systemic isotretinoin therapy

Most Cutaneous Procedures Seem Safe During Isotretinoin Rx

Mechanical dermabrasion and fully ablative laser not recommended in setting of systemic treatment
High levels of anxiety and depression in patients with facial acne are not related to oxidative stress

Acne-Related Depression, Anxiety Not Tied to Oxidative Stress

Anxiety more common than depression and directly associated with quality of life impairment