Here are what the editors at HealthDay consider to be the most important developments in Pathology for September 2017. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.
Upper Abdominal Cancer Resections Up in Octogenarians
FRIDAY, Sept. 29, 2017 (HealthDay News) — Rates of major upper abdominal cancer resections in octogenarians are increasing, according to a study published online Sept. 7 in Cancer.
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Embezzlement Widespread in Medical Practices
FRIDAY, Sept. 29, 2017 (HealthDay News) — Embezzlement is widespread among medical practices, and knowing the warning signs is helpful for preventing it, according to an article published in Medical Economics.
Eyebank Corneal Tissue Prep May Increase Infection Risk
FRIDAY, Sept. 29, 2017 (HealthDay News) — Donor rim cultures are more likely to have detectable Candida growth in endothelial keratoplasty-processed eyes than for other uses, according to a study published online Sept. 28 in JAMA Ophthalmology.
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Accurate Lung Cancer Staging Depends on Quality Nodal Exam
FRIDAY, Sept. 29, 2017 (HealthDay News) — The prognostic value of pathologic nodal (pN) stratification depends on the thoroughness of nodal examination in the staging of non-small-cell lung cancer, according to a study published online Sept. 28 in JAMA Oncology.
Single Mutation Made Zika Virus More Virulent
FRIDAY, Sept. 29, 2017 (HealthDay News) — A single mutation in the Zika virus made it more virulent, contributing to the increased incidence of microcephaly, according to a study published online Sept. 28 in Science.
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End-Stage Renal Disease Patients’ Readmission Rate High
FRIDAY, Sept. 29, 2017 (HealthDay News) — Nearly a quarter of hospital admissions among patients with end-stage renal disease (ESRD) on hemodialysis (HD) have a subsequent 30-day unplanned readmission, according to a study published online Sept. 28 in the Clinical Journal of the American Society of Nephrology.
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Vi-Tetanus Toxoid Conjugate Vaccine Can Prevent Typhoid
FRIDAY, Sept. 29, 2017 (HealthDay News) — A Vi-tetanus toxoid conjugate vaccine is efficacious for prevention of typhoid fever, according to a study published online Sept. 28 in The Lancet.
Pioglitazone Improves Left Ventricular Diastolic Function
FRIDAY, Sept. 29, 2017 (HealthDay News) — Pioglitazone improves whole-body and myocardial insulin sensitivity, left ventricular (LV) diastolic function, and systolic function in patients with type 2 diabetes, according to a small study published online Sept. 22 in Diabetes Care.
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More Than 78 Percent of Health Care Personnel Receive Flu Shot
THURSDAY, Sept. 28, 2017 (HealthDay News) — More than 78 percent of health care personnel (HCP) and 53.6 percent of pregnant women received influenza vaccination during the 2016-2017 influenza season, according to two studies published in the Sept. 29 issue of Morbidity and Mortality Weekly Report.
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Propranolol Use Inversely Linked to Melanoma Recurrence
THURSDAY, Sept. 28, 2017 (HealthDay News) — For patients with melanoma, use of propranolol is associated with reduced risk of recurrence, according to a study published online Sept. 28 in JAMA Oncology.
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Immunochromatography Testing Differentiates Dengue, Zika
THURSDAY, Sept. 28, 2017 (HealthDay News) — A rapid immunochromatography approach can differentiate dengue virus (DENV) and Zika virus (ZIKV) cases, according to a study published online Sept. 27 in Science Translational Medicine.
FDA: New Glucose Monitoring System Eliminates Finger Pricks
THURSDAY, Sept. 28, 2017 (HealthDay News) — The FreeStyle Libre Flash Glucose Monitoring System has been approved by the U.S. Food and Drug Administration, making it the first sanctioned device to monitor blood glucose in adult patients with diabetes without the need for a finger prick.
Pneumococcal Vaccine for Only Half With Work-Related Asthma
WEDNESDAY, Sept. 27, 2017 (HealthDay News) — Adults with work-related asthma are more likely that those with non-work-related asthma to have received pneumococcal vaccination, although only 53.7 percent with work-related asthma have been vaccinated, according to a study published online Sept. 27 in the American Journal of Preventive Medicine.
Notification Rates of New HIV Diagnoses Up in Older Adults
WEDNESDAY, Sept. 27, 2017 (HealthDay News) — Notification rates of new HIV diagnoses in older adults increased in 16 European countries from 2004 to 2015, according to a study published online Sept. 26 in The Lancet HIV.
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Hereditary Hemochromatosis Patients Can Safely Donate Blood
WEDNESDAY, Sept. 27, 2017 (HealthDay News) — There is no evidence to support excluding patients with hereditary hemochromatosis (HH) from serving as blood donors, according to a review published online Sept. 13 in Hepatology.
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Infusion of Umbilical Cord Stem Cells Safe, Effective in HFrEF
WEDNESDAY, Sept. 27, 2017 (HealthDay News) — Intravenous infusion of umbilical cord-derived mesenchymal stem cells (UC-MSCs) is safe and efficacious for patients with heart failure and reduced ejection fraction (HFrEF), according to a study published online Sept. 26 in Circulation Research.
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Working With a Scribe Improves Physician Satisfaction
WEDNESDAY, Sept. 27, 2017 (HealthDay News) — Working with a scribe significantly improves physicians’ overall satisfaction, satisfaction with chart quality and accuracy, and charting efficiency, according to a study published online Sept. 11 in the Annals of Family Medicine.
VA Models Provide Guidance for Care of Hepatitis C Infection
WEDNESDAY, Sept. 27, 2017 (HealthDay News) — The U.S. Department of Veterans Affairs (VA) has developed models of care that can be used to reduce the overall burden of hepatitis C virus (HCV) infection, according to a study published online Sept. 25 in the Annals of Internal Medicine.
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Cancer Risk Up for RA Patients With Venous Thromboembolism
WEDNESDAY, Sept. 27, 2017 (HealthDay News) — Patients with rheumatoid arthritis (RA) and venous thromboembolism (VTE) have increased risk of cancer in the first year after VTE and during a longer follow-up period, according to a study published online Sept. 15 in the Journal of Thrombosis and Haemostasis.
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Chronic Respiratory Disease Mortality Up From 1980 to 2014
TUESDAY, Sept. 26, 2017 (HealthDay News) — From 1980 to 2014 there was a considerable increase in mortality from chronic respiratory diseases in the United States, according to a study published in the Sept. 26 issue of the Journal of the American Medical Association.
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Predictors of Death in Cirrhosis Include Age, BSA, MELD
TUESDAY, Sept. 26, 2017 (HealthDay News) — For patients with cirrhosis, predictors of death include age, body surface area (BSA), and Model for End-Stage Liver Disease (MELD), according to a study published online Sept. 13 in Hepatology.
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CYPC19*17 Allele May Influence Response to PPI Treatment
TUESDAY, Sept. 26, 2017 (HealthDay News) — Children with CYP2C19*17 alleles without corresponding loss-of-function alleles have longer times with pH <4 in response to proton pump inhibitor (PPI) medication, according to a study published online Sept. 8 in the Journal of Clinical Pharmacology.
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Ocular Histopathology Features Seen With Congenital Zika
MONDAY, Sept. 25, 2017 (HealthDay News) — Certain ocular histopathologic features are consistently found in fetuses with congenital Zika syndrome (CZS), according to a study published online Sept. 21 in JAMA Ophthalmology.
Worker Contribution to Health Benefits Up in 2017
MONDAY, Sept. 25, 2017 (HealthDay News) — In 2017, health benefits coverage remained stable, while workers faced considerable variation in costs, according to a report published online Sept. 19 in Health Affairs.
Air Pollution May Damage Kidneys
FRIDAY, Sept. 22, 2017 (HealthDay News) — Air pollution may lead to kidney damage, according to a study published online Sept. 21 in the Journal of the American Society of Nephrology.
APOE Allele Type Tied to Mortality Risk
FRIDAY, Sept. 22, 2017 (HealthDay News) — The apolipoprotein E (APOE) ε4 allele increases the risk of overall and cardiovascular mortality, while the APOE ε2 allele decreases the risk, according to a study published online Sept. 12 in the Journal of the American Geriatrics Society.
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Fasting Blood Glucose Trajectory May Predict Future MI
FRIDAY, Sept. 22, 2017 (HealthDay News) — For individuals without diabetes, certain fasting blood glucose (FBG) trajectories are associated with the risk of future myocardial infarction (MI), according to a study published online Sept. 8 in Diabetes Care.
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Concussion May Increase Multiple Sclerosis Risk
FRIDAY, Sept. 22, 2017 (HealthDay News) — Concussion during adolescence increases the risk of subsequent multiple sclerosis (MS) diagnosis, according to a study published online Sept. 4 in the Annals of Neurology.
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Serum Cystatin C Predicts Mortality With Cirrhotic Ascites
FRIDAY, Sept. 22, 2017 (HealthDay News) — Serum cystatin C level is an excellent predictor of mortality in patients with cirrhotic ascites, according to a study published online Sept. 14 in the Journal of Gastroenterology and Hepatology.
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Combination Strategy Could Be Key in HIV Prevention
THURSDAY, Sept. 21, 2017 (HealthDay News) — A combination antibody strategy could be the key to halting the spread of HIV, according to results from two experimental studies. The research was published Sept. 20 in Science and Science Translational Medicine.
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UV Exposure May Contribute to Impaired Fat Homeostasis
THURSDAY, Sept. 21, 2017 (HealthDay News) — Adipochemokines induced by ultraviolet (UV) light may play a role in reduction of lipogenesis in subcutaneous (SC) fat, according to a study published online Aug. 27 in the British Journal of Dermatology.
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Childhood-Onset IBD May Raise Risk of Cancer
THURSDAY, Sept. 21, 2017 (HealthDay News) — Children with inflammatory bowel disease (IBD) face an increased risk of cancer that persists into adulthood, and is especially elevated for gastrointestinal cancers, according to a study published online Sept. 20 in The BMJ.
Magnesium Levels Tied to Dementia Risk
WEDNESDAY, Sept. 20, 2017 (HealthDay News) — Magnesium levels, either too high or too low, are associated with an increased risk of dementia, according to a study published online Sept. 20 in Neurology.
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Insurer Market Power Lowers Providers’ Prices
WEDNESDAY, Sept. 20, 2017 (HealthDay News) — Insurers have the bargaining power to reduce provider prices in highly concentrated provider markets, according to a report published in the September issue of Health Affairs.
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Histamine May Play Role in Colorectal Tumorigenesis
WEDNESDAY, Sept. 20, 2017 (HealthDay News) — Administration of histamine-producing gut microbes to histidine decarboxylase (HDC)-deficient mice reduces inflammation and tumor formation, suggesting an innovative approach to colorectal cancer (CRC) prevention and treatment, according to an experimental study published online Sept. 13 in The American Journal of Pathology.
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Hen’s Egg Detectable in Dust Samples After Egg Consumption
WEDNESDAY, Sept. 20, 2017 (HealthDay News) — Following consumption of hen’s egg there is an increase in hen’s egg protein in house dust collected from the eating area and bed, according to a study published online Sept. 2 in Allergy.
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HBcrAg Levels Tied to Progression to Cirrhosis in HBV Carriers
WEDNESDAY, Sept. 20, 2017 (HealthDay News) — For hepatitis B virus (HBV) carriers, hepatitis B virus core-related antigen (HBcrAg) levels are associated with progression to cirrhosis, according to a study published online Sept. 15 in the Journal of Gastroenterology and Hepatology.
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Proton Pump Inhibitors Overused Worldwide
WEDNESDAY, Sept. 20, 2017 (HealthDay News) — Proton pump inhibitors (PPIs) are overused worldwide, with wide variation seen in the extent of inappropriate use, according to research published online Sept. 11 in the Journal of Clinical Pharmacy and Therapeutics.
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General, Central Obesity Linked to Specific Breast Cancer Risk
WEDNESDAY, Sept. 20, 2017 (HealthDay News) — General and central obesity are associated with breast cancer risk, with different effects on specific subtypes, according to a study published online Sept. 14 in The Oncologist.
Total of 0.21 Years Lost Due to Opioid-Related Poisoning Deaths
TUESDAY, Sept. 19, 2017 (HealthDay News) — From 2000 to 2015, drug-poisoning deaths contributed a loss of 0.28 years in life expectancy, according to a research letter published in the Sept. 19 issue of the Journal of the American Medical Association.
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Deaths, Cardiac Arrest Not Rare in Triathlon Participants
TUESDAY, Sept. 19, 2017 (HealthDay News) — The incidence of deaths or cardiac arrest is 1.74 per 100,000 USA Triathlon participants, according to a study published online Sept. 19 in the Annals of Internal Medicine.
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ACP Does Not Support Legalization of Assisted Suicide
TUESDAY, Sept. 19, 2017 (HealthDay News) — The American College of Physicians (ACP) does not support the legalization of physician-assisted suicide, a practice that raises ethical, clinical, and other concerns, according to a position paper published online Sept. 19 in the Annals of Internal Medicine.
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Anagliptin Effect on LDL in T2DM Via ApoB-100 Synthesis
TUESDAY, Sept. 19, 2017 (HealthDay News) — In patients with type 2 diabetes being treated with a dipeptidyl peptidase-4 inhibitor (DPP4-I), use of anagliptin (ANA) may improve low-density lipoprotein cholesterol (LDL-C) levels, with the effect mediated, at least partly, via suppression of apoB-100 synthesis, according to a study published online Aug. 29 in the Journal of Diabetes Investigation.
Half of Repeat Antibiotics in Australia Extend Initial Rx
TUESDAY, Sept. 19, 2017 (HealthDay News) — Half of repeat antibiotic dispensings in Australia are used to extend the initial course, according to a study published online Sept. 11 in the Journal of Pharmacy Practice and Research.
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Monthly Feedback Linked to Improved Colonoscopy Quality
TUESDAY, Sept. 19, 2017 (HealthDay News) — Monthly feedback significantly improves colonoscopy quality measures, but quarterly feedback does not, according to a study published online Sept. 11 in Gastroenterology and Hepatology.
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Metabolomic Profiles Differ With Macular Degeneration
TUESDAY, Sept. 19, 2017 (HealthDay News) — Patients with age-related macular degeneration (AMD) have altered plasma metabolomic profiles compared with those without the condition, according to a study published online Sept. 12 in Ophthalmology.
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PD-L1 Mainly Expressed in Metastatic CRC Lesions
MONDAY, Sept. 18, 2017 (HealthDay News) — Programmed death-ligand 1 (PD-L1) is primarily expressed in metastatic colorectal cancer (CRC) lesions, according to a study published online Aug. 29 in the Journal of Digestive Diseases.
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Drills Assess ER Response to Communicable Disease
MONDAY, Sept. 18, 2017 (HealthDay News) — A series of mystery patient drills was used to assess the emergency department response to patients with communicable disease of public health concern in New York City; the results were published in the Sept. 15 issue of the U.S. Centers for Disease Control and Prevention’s Morbidity and Mortality Weekly Report.
Expected Burden of Lung Cancer High for People Living With HIV
MONDAY, Sept. 18, 2017 (HealthDay News) — For people living with HIV (PLWH), the expected burden of lung cancer is high, if smoking habits do not change, according to a study published online Sept. 18 in JAMA Internal Medicine.
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Greater Benefit for Pioglitazone in High-Risk Patients Post Stroke
MONDAY, Sept. 18, 2017 (HealthDay News) — For patients after an ischemic stroke or transient ischemic attack, pioglitazone is associated with greater benefit for those at higher risk for stroke or myocardial infarction (MI), according to a study published online Sept. 18 in JAMA Neurology.
New Link Seen Between Gene Fusion and Bladder Cancer
MONDAY, Sept. 18, 2017 (HealthDay News) — The fibroblast growth factor receptor 3 (FGFR3) transforming acidic coiled-coil containing protein 3 (TACC3) (FT3) gene fusion recruits endogenous TACC3 away from the mitotic spindle, resulting in errors in chromosome segregation in bladder cancer cells, according to a study published online Aug. 30 in Open Biology.
Physicians Tweeting About Drugs May Have Conflict of Interest
FRIDAY, Sept. 15, 2017 (HealthDay News) — Most physicians on Twitter with a financial conflict of interest (FCOI) and frequent tweets mention specific drugs for which they have a conflict, according to a study published in the September issue of The Lancet Haematology.
Conjunctivitis Prevalence Higher for Adult Women Than Men
FRIDAY, Sept. 15, 2017 (HealthDay News) — Adult women have a higher prevalence of conjunctivitis than men, and cases peak in the spring, according to a research letter published online Sept. 14 in JAMA Ophthalmology.
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EHR Data May Beat Claims Data in Assessing Sepsis Incidence
FRIDAY, Sept. 15, 2017 (HealthDay News) — Sepsis is present in 6 percent of adult hospitalizations, with no change in incidence from 2009 to 2014 based on electronic health record (EHR) data in contrast to claims-based analyses, according to a study published online Sept. 13 in the Journal of the American Medical Association.
Sleep Quality, Duration Linked to CKD Progression
FRIDAY, Sept. 15, 2017 (HealthDay News) — Shorter sleep duration and poor sleep quality are associated with progression of chronic kidney disease (CKD), according to a study published online Sept. 14 in the Journal of the American Society of Nephrology.
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‘Science Spin’ Found Prevalent in Biomedical Literature
FRIDAY, Sept. 15, 2017 (HealthDay News) — Spin in biomedical literature (also referred to as “science hype”) is prevalent, with trials having the highest and greatest variability in the prevalence of spin, according to a review published online Sept. 11 in PLOS Biology.
Assay Can ID M. tuberculosis Resistance Mutations
THURSDAY, Sept. 14, 2017 (HealthDay News) — An automated molecular assay can detect Mycobacterium tuberculosis with resistance to drugs directly from sputum specimens, according to a study published in the Sept. 14 issue of the New England Journal of Medicine.
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Twenty-Seven Viruses Can Be Found in Human Semen
THURSDAY, Sept. 14, 2017 (HealthDay News) — Twenty-seven viruses can be found in human semen, according to a research letter published online Sept. 13 in the U.S. Centers for Disease Control and Prevention’s Emerging Infectious Diseases.
Mutational Signatures Can More Accurately ID MMR Deficiency
THURSDAY, Sept. 14, 2017 (HealthDay News) — Mutational signatures could more accurately identify mismatch repair (MMR)-deficiency than sequencing of MMR genes, according to a study published online Sept. 13 in Cancer Research.
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Greater Awareness Needed for Potential of T2DM Remission
THURSDAY, Sept. 14, 2017 (HealthDay News) — For many patients with type 2 diabetes, remission can be achieved with sustained weight loss of ~15 kg, yet this often flies under the radar for patients and clinicians alike, according to an analysis published online Sept. 13 in The BMJ.
Fibrous Dysplasia Associated With Increased Breast Cancer Risk
THURSDAY, Sept. 14, 2017 (HealthDay News) — Patients with fibrous dysplasia (FD) are at increased risk for breast cancer, according to a study published online Aug. 30 in the Journal of Bone and Mineral Research.
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AACR Releases 2017 Cancer Progress Report
WEDNESDAY, Sept. 13, 2017 (HealthDay News) — The age-adjusted U.S. cancer death rate decreased 25 percent from 1991 to 2014, which translates into 2.1 million fewer cancer deaths, according to an annual progress report published by the American Association for Cancer Research.
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Some Aspects of Empathy Improve During Medical Training
WEDNESDAY, Sept. 13, 2017 (HealthDay News) — Certain aspects of empathy improve during medical student training, according to a study published online Sept. 7 in Medical Education.
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USPSTF Backs Cervical Cancer Screening With Cytology or hrHPV
WEDNESDAY, Sept. 13, 2017 (HealthDay News) — The U.S. Preventive Services Task Force (USPSTF) recommends cervical cancer screening with cervical cytology alone every three years or screening with high-risk human papillomavirus (hrHPV) testing alone every five years in women ages 30 to 65 years. These findings form the basis of a draft recommendation statement published online Sept. 12 by the USPSTF.
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Intestinal Glucose Stimulation Has Anti-Incretin Effect
WEDNESDAY, Sept. 13, 2017 (HealthDay News) — Intestinal glucose stimulation has an anti-incretin effect, down regulating insulin sensitivity, according to a study published online Aug. 29 in Diabetes.
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β-Adrenergic Receptor Signaling Affects Tumor Microenvironment
WEDNESDAY, Sept. 13, 2017 (HealthDay News) — β2-adrenergic receptor (β-AR) signaling in host immune cells regulates CD8+ T-cell frequency and functional orientation within the tumor microenvironment, according to a study published online Aug. 17 in Cancer Research.
Vitamin D Deficiency Tied to Neuropathic Pain
WEDNESDAY, Sept. 13, 2017 (HealthDay News) — Vitamin D deficiency may be associated with increased neuropathic pain (NP) in patients with rheumatoid arthritis (RA), according to a study published online Aug. 31 in the International Journal of Rheumatic Diseases.
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miRNA Identified That Plays Role in Milk Allergy
WEDNESDAY, Sept. 13, 2017 (HealthDay News) — MiR-193a-5p is a post-transcriptional regulator of interleukin-4 (IL-4) expression and could have a role in children’s cow’s milk allergy (CMA), according to a study published online Aug. 30 in Allergy.
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Sentinel Lymph Node Dissection Non-Inferior to Axillary Node
WEDNESDAY, Sept. 13, 2017 (HealthDay News) — Ten-year overall survival for primary breast cancer patients treated with sentinel lymph node dissection (SLND) alone is similar to that seen in those treated with axillary lymph node dissection (ALND), according to a study published in the Sept. 12 issue of the Journal of the American Medical Association.
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Distal Bicep Tendon Rip Tied to Transthyretin Amyloidosis
TUESDAY, Sept. 12, 2017 (HealthDay News) — Rupture of the distal biceps tendon (RBT) in a patient with heart failure with preserved ejection fraction should raise suspicion for wild-type transthyretin amyloidosis (ATTRwt), according to a research letter published in the Sept. 12 issue of the Journal of the American Medical Association.
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Are Physicians Obligated to Help on Planes?
TUESDAY, Sept. 12, 2017 (HealthDay News) — Does being a physician carry a moral obligation to respond to calls for medical assistance on airplanes? That is the topic of an article published in the Sept. 12 issue of the Journal of the American Medical Association.
Chronic Dosing of Apricot Kernel Extract May Lead to Hypoxia
TUESDAY, Sept. 12, 2017 (HealthDay News) — Chronic dosing of apricot kernel extract can result in hypoxia and cyanide toxicity, according to a report published online Sept. 11 in BMJ Case Reports.
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2017 Standards of Medical Care in Diabetes Released
TUESDAY, Sept. 12, 2017 (HealthDay News) — Recommendations for the management and pharmacologic treatment of patients with diabetes have been updated; the new clinical guidelines were published online Sept. 12 in the Annals of Internal Medicine.
CDC: Human Campylobacter Linked to Pet Store Puppies
MONDAY, Sept. 11, 2017 (HealthDay News) — Bacterial infections that have sickened 39 people in seven states have been linked to puppies sold through Petland, a national pet store chain, U.S. health officials say.
Median Cost of Cancer Drug Development $648.0 Million
MONDAY, Sept. 11, 2017 (HealthDay News) — The median cost of cancer drug development is $648.0 million, and revenue after approval is substantial, according to a study published online Sept. 11 in JAMA Internal Medicine.
‘Modest at Best’ Discriminatory Ability for CBC Test in Infants
MONDAY, Sept. 11, 2017 (HealthDay News) — Complete blood cell count parameters at commonly used or optimal thresholds do not offer high accuracy in identifying invasive bacterial infections (IBIs) in febrile infants (≤60 days of age), according to a study published online Sept. 11 in JAMA Pediatrics.
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Zika Virus Preferentially Targets Glioblastoma Stem Cells
MONDAY, Sept. 11, 2017 (HealthDay News) — Zika virus (ZIKV) is an oncolytic virus that preferentially targets glioblastoma stem cells (GSCs), according to a study published online Sept. 5 in The Journal of Experimental Medicine.
Biomarkers Can Predict Rapid Drop in Renal Function in T2DM
MONDAY, Sept. 11, 2017 (HealthDay News) — Plasma biomarkers that may improve the prediction of rapid decline in renal function in type 2 diabetes have been identified, according to a study published online Aug. 29 in Diabetes Care.
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In HIV, Tissue Factor-Expressing Monocytes Trigger Coagulation
MONDAY, Sept. 11, 2017 (HealthDay News) — A specific subset of tissue factor (TF)-expressing monocytes persist after virological suppression and trigger the coagulation cascade by activating factor X in HIV, according to a study published online Aug. 30 in Science Translational Medicine.
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Risk of Prematurity, SGA Up for Women on Antiepileptic Drugs
MONDAY, Sept. 11, 2017 (HealthDay News) — Women on antiepileptic drugs (AEDs) during pregnancy for epilepsy or other indications are at increased risk of giving birth to premature and small-for-gestational-age (SGA) infants, according to a study published online Aug. 30 in the Annals of Neurology.
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Greater Height Tied to Higher Risk of Venous Thromboembolism
MONDAY, Sept. 11, 2017 (HealthDay News) — Height is an independent predictor of venous thromboembolism (VTE), according to a study published online Sept. 5 in Circulation: Cardiovascular Genetics.
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Airway Mucin Concentrations May Help Predict Chronic Bronchitis
FRIDAY, Sept. 8, 2017 (HealthDay News) — Airway mucin concentrations may be a marker for chronic bronchitis, according to a study published online Sept. 6 in the New England Journal of Medicine.
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Zoonotic Chlamydia caviae Tied to Community-Acquired Pneumonia
FRIDAY, Sept. 8, 2017 (HealthDay News) — Three cases of community-acquired pneumonia involving Chlamydia caviae after exposure to ill guinea pigs have been described, according to a research letter published online Sept. 6 in the New England Journal of Medicine.
Zika, Cobalamin C Deficiency Tied to Similar Retinal Problems
FRIDAY, Sept. 8, 2017 (HealthDay News) — Retinal maldevelopment associated with congenital Zika syndrome (CZS) is similar to the maldevelopment seen with cobalamin C (cblC) deficiency, according to a study published online Sept. 7 in JAMA Opthalmology.
Genetic Variants Tied to Preterm Birth, Gestational Length
FRIDAY, Sept. 8, 2017 (HealthDay News) — Several genetic variants are associated with gestational duration and preterm birth, according to study published online Sept. 6 in the New England Journal of Medicine.
Vaccine-Type HPV Rates Down for Unvaccinated Young Women
FRIDAY, Sept. 8, 2017 (HealthDay News) — From 2009-2010 to 2013-2014 there was a decrease in the prevalence of vaccine-type human papillomavirus (HPV) among unvaccinated young women aged 18 to 26 years, according to a study published online Sept. 7 in Obstetrics & Gynecology.
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Traditional Flu Tests Not as Accurate as Newer Tests
THURSDAY, Sept. 7, 2017 (HealthDay News) — Digital immunoassays (DIAs) and rapid nucleic acid amplification tests (NAATs) have higher sensitivities for detecting influenza than rapid influenza diagnostic tests (RIDTs), according to a review published online Sept. 4 in the Annals of Internal Medicine.
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Budget Cuts Threaten Research on Antimicrobial Resistance
THURSDAY, Sept. 7, 2017 (HealthDay News) — Proposed budget cuts could seriously hamper efforts to address antimicrobial resistance (AMR), according to an article published online Sept. 4 in the Annals of Internal Medicine.
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Third Dose of MMR Vaccine Could Help Curb Mumps Outbreaks
THURSDAY, Sept. 7, 2017 (HealthDay News) — A third dose of the measles-mumps-rubella (MMR) vaccine lowers the risk of mumps during an outbreak, according to a study published online Sept. 6 in the New England Journal of Medicine.
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Early Respiratory Infections Tied to Celiac in High-Risk Children
THURSDAY, Sept. 7, 2017 (HealthDay News) — A higher frequency of respiratory infections during the first two years of life is associated with an increased risk of celiac disease (CD) in genetically predisposed infants, according to a study published online Sept. 6 in Pediatrics.
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Strong Evidence for Healthy Lifestyle Reducing CRC Risk
THURSDAY, Sept. 7, 2017 (HealthDay News) — There is strong evidence that physical activity and a healthy diet reduce the risk of colorectal cancer, according to a report published online Sept. 7 by the American Institute for Cancer Research and the World Cancer Research Fund.
Sudden Cardiac Arrest After Food Linked to Brugada Syndrome
WEDNESDAY, Sept. 6, 2017 (HealthDay News) — Having a sudden cardiac arrest after eating a large bite of food may be an indication of Brugada syndrome, according to a case study published online Sept. 6 in Pediatrics.
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Mailed Invitations Increase CRC Screening Completion
WEDNESDAY, Sept. 6, 2017 (HealthDay News) — Mailed outreach invitations offering a fecal immunochemical test (FIT) or colonoscopy increase the proportion of participants completing colorectal cancer (CRC) screening, and providing specific reminders to general practitioners (GPs) improves participation in FIT screening, according to two studies published online Sept. 5 in the Journal of the American Medical Association.
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Islet-Released Mediators Impact Transplant Outcome
WEDNESDAY, Sept. 6, 2017 (HealthDay News) — Cytokines and chemokines produced by pancreatic islets in response to inflammatory and metabolic stress include interferon gamma-induced protein 10 (IP-10/CXCL10), which is associated with poor islet transplant outcomes, according to a study published in the September issue of Diabetes.
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Universal Sequencing of Cancer Genes Ups Mutation Detection
WEDNESDAY, Sept. 6, 2017 (HealthDay News) — Universal sequencing of a broad panel of cancer-related genes is associated with increased detection of potentially clinically significant heritable mutations, according to a study published online Sept. 5 in the Journal of the American Medical Association.
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Increase in Medical Exemptions From Immunization in California
WEDNESDAY, Sept. 6, 2017 (HealthDay News) — There was an increase in the number of children with medical exemptions (MEs) from immunization in California from 2015 to 2016 after elimination of personal belief exemptions (PBEs), according to a research letter published online Sept. 5 in the Journal of the American Medical Association.
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Docs Should Be Aware of Family Beliefs Regarding Nondisclosure
WEDNESDAY, Sept. 6, 2017 (HealthDay News) — Physicians should be aware of societal codes of conduct that affect family beliefs and behaviors regarding information disclosure to pediatric patients, according to a study published online Sept. 5 in JAMA Pediatrics.
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Care Process Use Linked to Reduced S. Aureus Mortality
WEDNESDAY, Sept. 6, 2017 (HealthDay News) — Use of evidence-based care processes in routine care for Staphylococcus aureus bacteremia is associated with reduced mortality, according to a study published online Sept. 5 in JAMA Internal Medicine.
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Re-Analysis Shows Screening Reduces Prostate CA Mortality
TUESDAY, Sept. 5, 2017 (HealthDay News) — Re-analysis of evidence suggests that screening does reduce prostate cancer mortality, according to a study published online Sept. 4 in the Annals of Internal Medicine.
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General Anesthesia in Infants May Affect White Matter Volume
TUESDAY, Sept. 5, 2017 (HealthDay News) — Infants who receive general anesthesia for surgery before they’re 1 year old may have less white matter in their brains, according to research published online Aug. 24 in Anesthesiology.
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CRP, PCT Added to MELD Ups Prediction of Mortality in Cirrhosis
TUESDAY, Sept. 5, 2017 (HealthDay News) — For patients with cirrhosis, addition of C-reactive protein (CRP) and/or procalcitonin (PCT) to the model for end-stage liver disease (MELD) score improves prediction of mortality, according to a study published online Aug. 25 in the Journal of Gastroenterology and Hepatology.
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CYP2C9 Variants Linked to Clinical Events in VTE
TUESDAY, Sept. 5, 2017 (HealthDay News) — For elderly patients treated with vitamin K antagonists for venous thromboembolism (VTE), CYP2C9 variants are associated with any clinical event, according to a study published online Aug. 22 in the Journal of Thrombosis and Haemostasis.
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Goshuyuto, Rabeprazole Shown to Treat Refractory H. pylori
TUESDAY, Sept. 5, 2017 (HealthDay News) — Refractory Helicobacter pylori (HP) infection can be successfully treated with goshuyuto and rabeprazole, according to a case report published online Aug. 28 in the Journal of Digestive Diseases.
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Climate Change May Be the Cause of More Roadway Deaths
FRIDAY, Sept. 1, 2017 (HealthDay News) — America’s roads may become more dangerous as an unexpected consequence of climate change, according to a report published online Aug. 31 in Injury Prevention.
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Child Flu Vaccination Down When Nasal Spray Unavailable
FRIDAY, Sept. 1, 2017 (HealthDay News) — Seasonal flu immunization rates among children appear to have dropped slightly after the U.S. Centers for Disease Control and Prevention recommended against the nasal spray version of the vaccine, according to a study published online recently in Vaccine.
CDC: Fentanyl Driving Rise in Opioid-Linked Deaths in U.S.
FRIDAY, Sept. 1, 2017 (HealthDay News) — Fentanyl is a key player in America’s continuing epidemic of opioid-related overdose deaths, according to two reports published in the Sept. 1 issue of the U.S. Centers for Disease Control and Prevention’s Morbidity and Mortality Weekly Report.
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β-2 Adrenergic Agonists May Help Fight Parkinson’s Disease
FRIDAY, Sept. 1, 2017 (HealthDay News) — β-2 adrenergic agonists might be able to combat Parkinson’s disease, according to a study published in the Sept. 1 issue of Science.
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Crosstalk Identified Between Adipose Tissue, Carcinomas
FRIDAY, Sept. 1, 2017 (HealthDay News) — There is organ-dependent crosstalk between adipose tissue and carcinomas in various organs, according to a review published in the September issue of Cancer Prevention Research.
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Low Tumor Growth Rates During Active Surveillance of Thyroid CA
FRIDAY, Sept. 1, 2017 (HealthDay News) — Among patients with low-risk papillary thyroid cancer (PTC), the rates of tumor growth during active surveillance are low, according to a study published online Aug. 31 in JAMA Otolaryngology-Head & Neck Surgery.
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