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Review Suggests Benefits of Aerobic Exercise in Fibromyalgia

Improvements in HRQOL, pain, fatigue, physical function; no lasting impact on HRQOL, fatigue

Centralized Mailings Can Improve CRC Screening Adherence

Participants randomized to receive mailings had 31 percent more adjusted covered time over five years

Genetic Variation Impacts Pharmacokinetics of Exemestane

Significant differences in plasma exemestane area under the curve for OATP1B1 genotype groups

Moderate, Vigorous Activity Not Tied to More Elderly Falls

Falls in older women with high levels of physical activity also not more injurious

Stopping Statins After Initial Stroke Raises Risk of Recurrence

Findings based on patients discontinuing therapy three to six months after stroke

Ipragliflozin Beneficial in T2DM Complicated by Liver Disease

Effect similar to pioglitazone, with reduction in body weight, abdominal fat only for ipragliflozin

FDA Approves Imbruvica to Treat Chronic Graft Versus Host Disease

Drug sanctioned for patients with cGVHD who do not respond to other forms of therapy

Signature ID’d for Allergen-Specific Type 2 Helper Cells

Method for identifying pathogenic T cells implicated in allergic response may allow use as biomarker, target

IgG-Degrading Enzyme Allows HLA-Incompatible Transplant

IgG-degrading enzyme from Streptococcus pyogenes reduces, eliminates donor-specific antibodies

Are Clinicians Overprescribing Gabapentinoids for Pain?

Non-trivial side effects, no robust evidence for off-label use of gabapentinoids for other types of pain