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Biennial biopsies are an acceptable alternative to annual biopsies for men managing low-risk prostate cancer through active surveillance

Less Frequent Biopsy May Be Option in Prostate Cancer Care

Consequences of biennial versus annual biopsies similar during active surveillance
Heart rate variability and specific inflammatory biomarkers can differentiate major depressive disorder from depression in bipolar disorder

Simple ECG May Help Distinguish MDD From Bipolar Depression

Higher low-frequency heart rate variability, lower levels of IL-10 and MCP-1 for major depression
For reversal of opioid overdose

Similar Efficacy for Intranasal, Intramuscular Naloxone

Similar efficacy for higher-concentration intranasal naloxone, IM naloxone administered at same dose
The five-year risks of cervical intraepithelial neoplasia grade 3 (CIN3)

Risk of ≥CIN3 Drops With Negative HPV, Cytology Co-Tests

Decrease in 5-year ≥CIN3 risks after each successive negative round of HPV, cytology co-testing
For infants with bronchiolitis

Practice Variation in Treatment for Bronchiolitis in Infants

Variation in evidence-based supportive therapies by site, ranging from 6 to 99 percent
For patients with atrial fibrillation and prior cerebrovascular accident

Ablation Cuts Risk of Recurrent Stroke in Patients With A-Fib

Patients with AF with no ablation have increased five-year risk of CVA, death versus ablated patients
Cardiovascular disease hospitalization rates have declined in recent years among individuals with and those without diabetes

1998 to 2014 Saw Drop in CVD Hospitalization Rates in Diabetes

Rates of CVD hospitalizations remained two to four times higher for those with versus without diabetes
For patients with human papillomavirus-associated cancers

Sex, Race, Age Disparities in Survival for HPV-Linked Cancer

Whites have consistently higher five-year survival than blacks for all cancers across all age groups
Single measles cases trigger coordinated public health action that is associated with considerable costs

Considerable Costs Incurred in Response to Single Measles Cases

Public health costs of disease investigation for two single measles cases estimated at $49,769, $18,423
For patients with heart failure with preserved ejection fraction

Abdominal Obesity Linked to All-Cause Mortality in HFpEF

Increased risk of all-cause, cardiovascular, non-cardiovascular mortality in patients with HFpEF