Here are what the editors at HealthDay consider to be the most important developments in Gastroenterology for January 2017. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.
Review: Cardiopulmonary Event Rate Not Up With Propofol Use
TUESDAY, Jan. 31, 2017 (HealthDay News) — The risk of cardiopulmonary adverse events is similar for propofol sedation and traditional sedation agents for gastrointestinal endoscopic procedures, according to a review published in the February issue of Clinical Gastroenterology and Hepatology.
Dietary Factors Linked to Risk of Acute Pancreatitis
MONDAY, Jan. 30, 2017 (HealthDay News) — Dietary factors are associated with pancreatitis, with saturated fat and cholesterol positively linked to gallstone-related acute pancreatitis (AP), according to a study published in the February issue of Clinical Gastroenterology and Hepatology.
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Microbiota Transfer Therapy Could Help Children With Autism
FRIDAY, Jan. 27, 2017 (HealthDay News) — A new approach to alter the gut microbiome and virome may be an effective treatment for children with autism spectrum disorder (ASD), according to research published online Jan. 23 in Microbiome.
Antibiotics, Not Poor Hygiene, Main Cause of C. difficile Outbreak
FRIDAY, Jan. 27, 2017 (HealthDay News) — Reducing the use of fluoroquinolones has curbed an outbreak of Clostridium difficile that began in 2006 in England, according to a study published online Jan. 24 in The Lancet Infectious Diseases.
Risk of Diabetes Down With HCV SVR in HIV/HCV Coinfection
FRIDAY, Jan. 27, 2017 (HealthDay News) — In patients co-infected with HIV and hepatitis C virus (HCV), eradication of HCV is associated with a reduction in the risk of diabetes mellitus, according to a study published online Jan. 21 in Hepatology.
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Anxiety, Depression May Up Mortality Risk for Some Cancers
THURSDAY, Jan. 26, 2017 (HealthDay News) — Anxiety and depression may increase the risk of death from certain cancers, according to research published online Jan. 25 in The BMJ.
Bezlotoxumab Promising Against Recurrent Clostridium difficile
THURSDAY, Jan. 26, 2017 (HealthDay News) — Bezlotoxumab (Zinplava) is effective in reducing the risk of recurrent Clostridium difficile infection, according to research published in the Jan. 26 issue of the New England Journal of Medicine.
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Most PCPs Oppose Complete Repeal of the Affordable Care Act
THURSDAY, Jan. 26, 2017 (HealthDay News) — A majority of primary care doctors oppose full repeal of the Affordable Care Act, according to a perspective piece published online Jan. 25 in the New England Journal of Medicine.
Strategies Presented for Addressing Uncompensated Time
THURSDAY, Jan. 26, 2017 (HealthDay News) — Strategies can be employed to help physicians deal with the increasing burden of uncompensated tasks, according to an article published in Medical Economics.
Chemo May Be Overused in Younger Patients With Colon CA
WEDNESDAY, Jan. 25, 2017 (HealthDay News) — Young and middle-aged colon cancer patients may be getting chemotherapy more often than is warranted, according to a study published online Jan. 25 in JAMA Surgery.
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‘Opt Out’ Doesn’t Increase Access to Anesthesia Care
WEDNESDAY, Jan. 25, 2017 (HealthDay News) — The “opt out” rule, which allows U.S. states to opt out of the regulations requiring physician supervision of nurse anesthetists has not increased access to anesthesia care for certain common procedures, according to a study published online Jan. 19 in Anesthesiology.
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FDA Approves Trulance for Chronic Idiopathic Constipation
FRIDAY, Jan. 20, 2017 (HealthDay News) — Trulance (plecanatide) has been approved by the U.S. Food and Drug Administration to treat persistent idiopathic constipation in adults.
Obesity Underrepresented in Medical Licensing Exams
FRIDAY, Jan. 20, 2017 (HealthDay News) — The most important concepts of obesity prevention and treatment are not adequately represented on the U.S. Medical Licensing Examination (USMLE) Step examinations, according to a study published recently in Teaching and Learning in Medicine.
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Type 1 Diabetes Tied to Gut Inflammation, Microbiota
FRIDAY, Jan. 20, 2017 (HealthDay News) — Patients with type 1 diabetes exhibit inflammation in the digestive tract and gut bacteria in a pattern that differs from individuals who do not have diabetes or those who have celiac disease, according to a study published online Jan. 19 in the Journal of Clinical Endocrinology & Metabolism.
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CpG Island Methylator Phenotype Prognostic After CRC Surgery
THURSDAY, Jan. 19, 2017 (HealthDay News) — For patients undergoing colorectal cancer (CRC) surgery, CpG island methylator phenotype (CIMP) status predicts survival, according to research published online Jan. 14 in the Journal of Gastroenterology and Hepatology.
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Physician Excess Charges Create Financial Burden for Patients
TUESDAY, Jan. 17, 2017 (HealthDay News) — Many doctors bill their private-paying patients two, three, even six times more than what Medicare pays for the same services, according to a research letter published in the Jan. 17 issue of the Journal of the American Medical Association.
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Addition of Cetuximab to CRT Cuts Locoregional Failure in Anal CA
MONDAY, Jan. 16, 2017 (HealthDay News) — Addition of cetuximab to chemoradiation (CRT) is associated with a reduction in locoregional failure (LRF) rates in squamous cell carcinoma of the anal canal (SCCAC), according to a study published online Jan. 9 in the Journal of Clinical Oncology.
Educational Methods Have Improved Bowel Prep Compliance
MONDAY, Jan. 16, 2017 (HealthDay News) — Recently developed educational methods have improved patient compliance with bowel preparation for colonoscopy, according to a review published online Jan. 5 in the Journal of Digestive Diseases.
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Fecal Transplant No Better Than Oral Antibiotic for C. difficile
FRIDAY, Jan. 13, 2017 (HealthDay News) — A single fecal transplant delivered by enema is apparently no more effective than oral antibiotics in treating recurring cases of Clostridium difficile infection, according to research published recently in Clinical Infectious Diseases.
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Tapeworm From Asian Waters Identified in Alaskan Salmon
FRIDAY, Jan. 13, 2017 (HealthDay News) — A tapeworm known to infect salmon from the Asian Pacific is also present in fish from U.S. waters, according to research published in the February issue of the U.S. Centers for Disease Control and Prevention’s Emerging Infectious Diseases.
177Lu-Dotatate Ups PFS in Midgut Neuroendocrine Tumors
THURSDAY, Jan. 12, 2017 (HealthDay News) — For patients with advanced midgut neuroendocrine tumors, lutetium-177 (177Lu)-Dotatate is associated with longer progression-free survival than high-dose octreotide long-acting repeatable (LAR), according to a study published in the Jan. 12 issue of the New England Journal of Medicine.
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Gut Metabolite May Help Predict Cardiovascular Mortality Risk
WEDNESDAY, Jan. 11, 2017 (HealthDay News) — A metabolite produced in the digestion of red meat, eggs, and dairy products — trimethylamine N-oxide (TMAO) — is linked to an increased risk of a fatal myocardial infarction or stroke, according to a study published online Jan. 11 in the European Heart Journal.
Excessive FDA Regulation Driving High Drug Prices
WEDNESDAY, Jan. 11, 2017 (HealthDay News) — The excessive regulatory regime at the U.S. Food and Drug Administration is an important driver of high drug prices, and should be curbed to introduce more competition and lower prices, according to a report published online Jan. 5 by the National Center for Policy Analysis.
Novel Diet Can Help Children With Crohn’s, Colitis Find Relief
TUESDAY, Jan. 10, 2017 (HealthDay News) — Children with Crohn’s disease and ulcerative colitis may be able to achieve relief without medications by eating a special diet, according to a study published recently in the Journal of Clinical Gastroenterology.
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High Dietary Red Meat Intake Tied to Diverticulitis in Men
TUESDAY, Jan. 10, 2017 (HealthDay News) — Men who eat a lot of red meat may have a higher risk of diverticulitis, according to a study published online Jan. 9 in Gut.
Acid Suppression in Pregnancy Linked to Childhood Asthma
TUESDAY, Jan. 10, 2017 (HealthDay News) — Women who take acid-suppressing medications during pregnancy may have a child at increased risk of developing asthma, according to a review published online Jan. 9 in the Journal of Allergy and Clinical Immunology.
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Optimized Treatment Relieves Pain in Chronic Pancreatitis
TUESDAY, Jan. 10, 2017 (HealthDay News) — For most patients with chronic pancreatitis (CP), optimized medical and interventional treatment is associated with significant pain relief, according to a study published online Jan. 4 in the Journal of Gastroenterology and Hepatology.
Process-of-Care Failures Common in Adults With Rectal Bleeding
MONDAY, Jan. 9, 2017 (HealthDay News) — Among adult primary care patients with rectal bleeding, process-of-care failures are frequent and are associated with poor or fair quality care, according to a study published in the January issue of The Joint Commission Journal on Quality and Patient Safety.
HRQoL Down for GERD With Laryngopharyngeal Reflux
MONDAY, Jan. 9, 2017 (HealthDay News) — For patients with gastroesophageal reflux disease (GERD), the presence of laryngopharyngeal reflux symptoms (LPR) is associated with reduced health-related quality of life (HRQoL), according to a study published online Jan. 3 in the Journal of Gastroenterology and Hepatology.
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Very Obese Teens Benefit From Gastric Bypass Over Long Term
FRIDAY, Jan. 6, 2017 (HealthDay News) — Weight-loss surgery helps severely obese teens maintain weight loss over the long term; however, some young people may need additional surgery to manage complications associated with their rapid post-surgery weight loss, and some may also develop nutritional deficiencies, according to two studies published online Jan. 5 in The Lancet Diabetes & Endocrinology.
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Sorafenib Effect on HCC Survival Depends on Hepatitis Status
FRIDAY, Jan. 6, 2017 (HealthDay News) — For patients with advanced unresectable hepatocellular carcinoma, the effect of sorafenib on overall survival (OS) is dependent on patients’ hepatitis status, according to a meta-analysis published online Jan. 3 in the Journal of Clinical Oncology.
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Acid Suppression Rx Linked to Risk of C. difficile, Campylobacter
FRIDAY, Jan. 6, 2017 (HealthDay News) — Proton pump inhibitor (PPI) and H2 receptor antagonist (H2RA) users may be at higher risk of infection with Clostridium difficile and Campylobacter bacteria, according to a study published online Jan. 5 in the British Journal of Clinical Pharmacology.
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Cancer Mortality Rates Continue to Decline in the United States
THURSDAY, Jan. 5, 2017 (HealthDay News) — Cancer mortality rates in the United States have dropped 25 percent since the early 1990s, according to a new report published online Jan. 5 in CA: A Cancer Journal for Clinicians.
Non-Liver-Related Critical Events Down With SVR in HCV+Cirrhosis
WEDNESDAY, Jan. 4, 2017 (HealthDay News) — For patients with hepatitis C virus (HCV) infection and biopsy-proven cirrhosis, sustained viral response (SVR) is associated with a reduction in critical events, both liver and non-liver related, according to research published in the January issue of Gastroenterology.
Lifestyle Intervention Reduces Portal Pressure in Cirrhosis
WEDNESDAY, Jan. 4, 2017 (HealthDay News) — For overweight/obese patients with compensated cirrhosis and portal hypertension, a lifestyle intervention can reduce body weight and portal pressure, according to a study published online Dec. 20 in Hepatology.
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Metformin Tied to Better Clinical Outcomes in CKD, CHF, CLD
WEDNESDAY, Jan. 4, 2017 (HealthDay News) — For patients with chronic kidney disease (CKD), congestive heart failure (CHF), or chronic liver disease (CLD) with hepatic impairment, metformin use is associated with improvements in clinical outcomes, according to a review published online Jan. 3 in the Annals of Internal Medicine.
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Pelvic Physical Therapy Effective for Functional Constipation
TUESDAY, Jan. 3, 2017 (HealthDay News) — For children with functional constipation (FC), pelvic physical therapy (PPT) is more effective than standard medical care (SMC) for almost all outcomes measured, according to a study published in the January issue of Gastroenterology.
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