Home Pediatrics February 2020 Briefing – Pediatrics

February 2020 Briefing – Pediatrics

Here are what the editors at HealthDay consider to be the most important developments in Pediatrics for February 2020. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

HIV-Infected Youth Less Likely to Achieve Viral Suppression

FRIDAY, Feb. 28, 2020 (HealthDay News) — Youth newly diagnosed with HIV are linked to care at similar rates as adults but achieve disproportionately lower rates of viral suppression, according to a study published online Jan. 28 in the Journal of Acquired Immune Deficiency Syndrome.

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Age of Onset May Affect Clinical Outcomes for MS Patients on DMT

FRIDAY, Feb. 28, 2020 (HealthDay News) — Age of onset for disease is an important factor affecting clinical outcomes across the life span in patients receiving disease-modifying therapy (DMT) for multiple sclerosis (MS), according to a study published online Feb. 25 in the European Journal of Neurology.

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Recommendations Issued for R/R Pediatric Hodgkin Lymphoma

THURSDAY, Feb. 27, 2020 (HealthDay News) — In a EuroNet Pediatric Hodgkin Lymphoma Group guideline, published in the February issue of HemaSphere, recommendations are presented regarding salvage therapy for pediatric patients with first relapse or refractory (R/R) classical Hodgkin lymphoma (cHL).

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NIH Toolbox Cognitive Battery Valid in Intellectual Disability

THURSDAY, Feb. 27, 2020 (HealthDay News) — The NIH-Toolbox Cognitive Battery (NIHTB-CB) is reliable and valid for children and young adults with intellectual disability (ID), according to a study published online Feb. 24 in Neurology.

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Video Game-Like Intervention May Aid Children With ADHD

THURSDAY, Feb. 27, 2020 (HealthDay News) — Among children with attention-deficit/hyperactivity disorder (ADHD), performance in attentional functioning was significantly improved at four weeks in those receiving a digital intervention versus control sessions, according to a study published online Feb. 24 in The Lancet Digital Health.

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States Launch Investigation of Juul Labs

WEDNESDAY, Feb. 26, 2020 (HealthDay News) — The marketing and sales of vaping products by San Francisco-based Juul Labs is being investigated by 39 states.

AP News Article

Influence of Politics Has Not Waned in Opinions About ACA

WEDNESDAY, Feb. 26, 2020 (HealthDay News) — Public opinion about the Affordable Care Act (ACA) remains divided 10 years after its passage, according to a study published online Feb. 19 in Health Affairs.

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Mistreatment, Discrimination Still Common for Medical Students

TUESDAY, Feb. 25, 2020 (HealthDay News) — Mistreatment of medical students remains common for women, racial/ethnic minorities, and sexual minorities, according to a study published online Feb. 24 in JAMA Internal Medicine.

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Guidance Issued for Food Intake in Inflammatory Bowel Disease

TUESDAY, Feb. 25, 2020 (HealthDay News) — In an article from the International Organization for the Study of Inflammatory Bowel Disease, published online Feb. 14 in Clinical Gastroenterology and Hepatology, recommendations are presented regarding specific food consumption for patients with inflammatory bowel disease (IBD).

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Tax on Sweetened Beverages Reduced Sales Volume in Chicago

TUESDAY, Feb. 25, 2020 (HealthDay News) — The Cook County Sweetened Beverage Tax (SBT) led to a substantial reduction in the volume sold of taxed beverages, according to a study published online Feb. 25 in the Annals of Internal Medicine.

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Daily Emollient in Infancy Does Not Foil Eczema in Children at Risk

MONDAY, Feb. 24, 2020 (HealthDay News) — Daily emollient during the first year of life does not prevent eczema in high-risk children, according to a study published online Feb. 19 in The Lancet.

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AAP: Pediatricians Should Promote Physical Activity in Children

MONDAY, Feb. 24, 2020 (HealthDay News) — Pediatricians should promote physical literacy and activity in children, according to an American Academy of Pediatrics clinical report published online Feb. 24 in Pediatrics.

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Children’s Vaccine Patterns Mainly Classified as Recommended

MONDAY, Feb. 24, 2020 (HealthDay News) — Most children’s vaccination patterns are classified as recommended, although a considerable proportion are not up to date with vaccinations by 19 to 35 months of age, according to a study published online Feb. 21 in Pediatrics.

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Most Doctors Perceive Benefits of Vaccines for Children Program

FRIDAY, Feb. 21, 2020 (HealthDay News) — Most pediatricians report that the Vaccines for Children Program (VFC) has high perceived benefits, according to a study published online Feb. 21 in Pediatrics.

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Major Malformations Up With Macrolide Prescribing in Pregnancy

FRIDAY, Feb. 21, 2020 (HealthDay News) — Prescribing macrolide antibiotics during the first trimester of pregnancy is associated with an increased risk for major fetal malformation, according to a study published online Feb. 19 in The BMJ.

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Cancer Therapy-Associated Polyposis May Mimic CRC Predisposition

FRIDAY, Feb. 21, 2020 (HealthDay News) — Childhood and young adulthood cancer (CYAC) therapy-associated polyposis (TAP) often has clinical features suggestive of at least one colorectal cancer (CRC) predisposition syndrome, according to a study published online Feb. 12 in Cancer Prevention Research.

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Ultrasound May ID Children at Risk for Cystic Fibrosis Liver Disease

THURSDAY, Feb. 20, 2020 (HealthDay News) — A heterogeneous pattern on ultrasound examination of the liver may help identify children with cystic fibrosis (CF) at increased risk for developing advanced CF liver disease, according to a study published online Feb. 12 in The Journal of Pediatrics.

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Late Mortality Up for Survivors of Early-Teen, Young Adult Cancers

THURSDAY, Feb. 20, 2020 (HealthDay News) — Early-adolescent and young adult cancer survivors have increased mortality and morbidity risks compared with siblings or the general population, according to a study published online Feb. 14 in The Lancet Oncology.

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Vaccine Effectiveness 45 Percent for Flu Virus Linked to ARI

THURSDAY, Feb. 20, 2020 (HealthDay News) — The overall vaccine effectiveness (VE) against any influenza virus associated with medically attended acute respiratory illness (ARI) is 45 percent for the current influenza season, according to research published in the Feb. 21 issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.

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Many Transgender Youth Intentionally Avoid Disclosure

THURSDAY, Feb. 20, 2020 (HealthDay News) — Most transgender youth voluntarily disclose their gender identity to health care providers (HCPs) outside of a gender clinic; however, almost half report having intentionally avoided disclosure, according to a study published online Feb. 20 in the Journal of Adolescent Health.

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Developmental Disability Diagnosis More Likely in Rural Children

THURSDAY, Feb. 20, 2020 (HealthDay News) — Children living in rural areas are more likely to be diagnosed with a developmental disability compared with those living in urban areas, according to a study published online Feb. 19 in National Health Statistics Reports, a publication from the U.S. Centers for Disease Control and Prevention.

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Survival After Pediatric Kidney Transplant Drastically Improved

THURSDAY, Feb. 20, 2020 (HealthDay News) — There has been an increase in survival after pediatric kidney transplantation since 1970, according to a study published online Feb. 13 in the Clinical Journal of the American Society of Nephrology.

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Most Youth With Chronic Fatigue Syndrome Undiagnosed

WEDNESDAY, Feb. 19, 2020 (HealthDay News) — Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) remains largely undiagnosed in youth, according to a study published online Jan. 23 in the Child & Youth Care Forum.

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Moderate-to-Late Preemies Likely Go Home at 36 Weeks

WEDNESDAY, Feb. 19, 2020 (HealthDay News) — Moderate-to-late preterm babies (born at a gestational age of 32 to 36 weeks) with no significant medical problems on admission are likely to be discharged at 36 weeks of postmenstrual age, according to a study recently published in the American Journal of Perinatology.

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Prenatal Exposure to Phthalates Tied to Autistic Traits in Children

WEDNESDAY, Feb. 19, 2020 (HealthDay News) — Gestational exposure to phthalates is associated with higher scores on the Social Responsiveness Scale II (SRS-2), as a measure of autistic traits and social impairment, according to a study published online Feb. 19 in Environmental Health Perspectives.

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One-Quarter of Antibiotic Prescriptions at Children’s Hospitals Suboptimal

WEDNESDAY, Feb. 19, 2020 (HealthDay News) — One in three children are prescribed antibiotics at children’s hospitals, and 25.9 percent prescribed antibiotics for infectious use are receiving at least one suboptimal antibiotic, according to a study recently published in Clinical Infectious Diseases.

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Late Sleep May Raise Risk for Adiposity in Young Children

WEDNESDAY, Feb. 19, 2020 (HealthDay News) — More frequent exposure to late sleep is associated with increases in adiposity in children aged 2 to 6 years, especially among those with overweight and/or obese parents, according to a study published online Feb. 18 in Pediatrics.

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Rx Meds That Children Access Often Removed From Packaging

TUESDAY, Feb. 18, 2020 (HealthDay News) — More than half of prescription medication exposures among children involve access to medications that have previously been removed from their original packaging, according to a study published online Feb. 11 in The Journal of Pediatrics.

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Low-Cost Marketing of Stimulants to Physicians May Increase Rx Rates

TUESDAY, Feb. 18, 2020 (HealthDay News) — Low-cost marketing to physicians may be driving up stimulant prescribing rates, according to a research letter published online Jan. 21 in JAMA Pediatrics.

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AAP Addresses Fertility Preservation for Children With Cancer

TUESDAY, Feb. 18, 2020 (HealthDay News) — Medical and ethical considerations of fertility preservation in children with cancer are addressed in a clinical report from the American Academy of Pediatrics, published online Feb. 18 in Pediatrics.

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Wheeze, Asthma Risk Up With Cleaning Product Use Exposure in Infancy

TUESDAY, Feb. 18, 2020 (HealthDay News) — Infants in homes with frequent use of household cleaning products have an increased risk for childhood wheeze and asthma, according to a study published online Feb. 18 in CMAJ, the journal of the Canadian Medical Association.

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U.S. Life Expectancy to Reach 85 by 2060

FRIDAY, Feb. 14, 2020 (HealthDay News) — Nearly a quarter of all U.S. residents will be older than 65 by 2060, and life expectancy will reach an all-time high of 85 by that year, according to the U.S. Census Bureau.

AP News Article

Medtronic MiniMed 600 Series Insulin Pumps Recalled

FRIDAY, Feb. 14, 2020 (HealthDay News) — More than 322,000 MiniMed 600 Series Insulin Pumps have been recalled by Medtronic due to a defect that could cause them to malfunction and put users at risk for serious harm or death.

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Teens With ADHD Less Likely Than Preteens to Have Doctor Visit

FRIDAY, Feb. 14, 2020 (HealthDay News) — Children with attention-deficit/hyperactivity disorder (ADHD) are less likely to have a primary care visit during adolescence than preadolescence, according to a study published in the February/March issue of the Journal of Developmental & Behavioral Pediatrics.

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Short-Course Rifamycin-Based Regimens Preferred for Latent TB

FRIDAY, Feb. 14, 2020 (HealthDay News) — For treatment of latent tuberculosis infection (LTBI), short-course rifamycin-based regimens are preferred over longer-course isoniazid monotherapy, according to guidelines published in the Feb. 14 issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.

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Cool Water for 20 Minutes After Pediatric Burn Improves Outcomes

FRIDAY, Feb. 14, 2020 (HealthDay News) — Cooling children’s burns with running water improves clinical outcomes, according to a study published in the January issue of the Annals of Emergency Medicine.

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No Sign of Vertical Transmission of COVID-19 Found in Late Pregnancy

THURSDAY, Feb. 13, 2020 (HealthDay News) — There currently is no evidence of intrauterine infection caused by vertical transmission in women who develop 2019 novel coronavirus disease (COVID-19) pneumonia in late pregnancy, according to research published online Feb. 12 in The Lancet.

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2002 to 2015 Saw Increase in Incidence of Diabetes in Youth

THURSDAY, Feb. 13, 2020 (HealthDay News) — From 2002 to 2015, there was a constant increase in the incidence of type 1 and type 2 diabetes among youth, according to research published in the Feb. 14 issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.

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Sedentary Behavior, Activity Linked to Depression at Age 18

THURSDAY, Feb. 13, 2020 (HealthDay News) — Sedentary behavior throughout adolescence is associated with the risk for depressive symptoms at age 18 years, according to a study published online Feb. 11 in The Lancet Psychiatry.

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Recommendations Issued for Sleep Disturbance in Pediatric Autism

WEDNESDAY, Feb. 12, 2020 (HealthDay News) — In an American Academy of Neurology practice guideline, published online Feb. 12 in Neurology, recommendations are presented for addressing sleep disturbances in children and adolescents with autism spectrum disorder (ASD).

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2011 to 2018 Saw Decline in Problems Paying Medical Bills

WEDNESDAY, Feb. 12, 2020 (HealthDay News) — From 2011 to 2018, there was a decrease in the percentage of families having problems paying medical bills in the past 12 months, according to a February data brief published by the U.S. Centers for Disease Control and Prevention National Center for Health Statistics.

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Young Cancer Survivors at Higher Risk for Hospitalization

WEDNESDAY, Feb. 12, 2020 (HealthDay News) — Adolescent and young adult (AYA) cancer survivors (aged 15 to 39 years) have an increased risk for inpatient hospitalization, according to a study published online Jan. 20 in Cancer Epidemiology, Biomarkers & Prevention.

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Elevated FPG May Increase Adverse Outcomes in GDM Pregnancies

TUESDAY, Feb. 11, 2020 (HealthDay News) — Elevated fasting plasma glucose, compared with elevated postload glucose, in pregnancies in women with gestational diabetes is associated with a higher risk for adverse maternal and infant outcomes, according to a study published in the January issue of Diabetic Medicine.

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Few Adolescent Men Who Have Sex With Men Have Had HIV Test

TUESDAY, Feb. 11, 2020 (HealthDay News) — Few adolescent men who have sex with men (AMSM) have had an HIV test, according to a study published online Feb. 11 in Pediatrics.

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Breast Development, Puberty Starting Earlier in Girls Worldwide

TUESDAY, Feb. 11, 2020 (HealthDay News) — Across the world, young women are entering puberty at increasingly earlier ages, according to a review published online Feb. 10 in JAMA Pediatrics.

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Prophylactic Migraine Treatment Has No Effect in Children

TUESDAY, Feb. 11, 2020 (HealthDay News) — There is little evidence supporting the efficacy of prophylactic pharmacologic treatments for pediatric migraine, according to a review published online Feb. 10 in JAMA Pediatrics.

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Broad Clinical Spectrum Linked to Pediatric MOG Antibodies

TUESDAY, Feb. 11, 2020 (HealthDay News) — The spectrum of pediatric syndromes associated with myelin oligodendrocyte glycoprotein (MOG) antibodies is wider than previously thought, according to a study published online Feb. 10 in The Lancet Neurology.

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CDC Outlines U.S. Process of Evaluating Patients for 2019-nCoV

MONDAY, Feb. 10, 2020 (HealthDay News) — Recognizing individuals at risk for 2019 novel coronavirus (2019-nCoV) infection is a key part of facilitating infection control and prevention and limiting transmission, according to research published in the Feb. 7 early-release issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.

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Medical Group Opposes States’ Limits on Trans Youth Access to Treatment

MONDAY, Feb. 10, 2020 (HealthDay News) — A group of medical professionals in southern states opposes proposals that would limit transgender minors’ access to gender-affirming health care such as hormone therapy and surgery.

CNN Article

Empathy Declines as Students Progress Through Medical School

MONDAY, Feb. 10, 2020 (HealthDay News) — Students become less empathic toward patients throughout medical school, according to a study published online Jan. 21 in Academic Medicine.

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Seniors Have Concerns About Affording Health Insurance

MONDAY, Feb. 10, 2020 (HealthDay News) — Many adults aged 50 to 64 years are concerned about their ability to afford health insurance, according to a study published online Feb. 7 in JAMA Network Open.

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Biologics Tied to Greater Reduction in Pediatric Psoriasis

MONDAY, Feb. 10, 2020 (HealthDay News) — Biologics seem to be associated with greater reduction in psoriasis severity scores and higher drug survival rates than methotrexate in pediatric patients treated in a real-world setting, according to a study published online Feb. 5 in JAMA Dermatology.

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Sexual Minority Youth More Likely to Attempt Suicide

MONDAY, Feb. 10, 2020 (HealthDay News) — More teenagers are identifying as sexual minorities, and sexual minority youth have high prevalence of suicidal ideation, plans, and attempts, according to two studies published online Feb. 10 in Pediatrics.

Abstract/Full Text – Raifman
Abstract/Full Text – Liu
Editorial

Higher Birth Weight May Improve Cardiorespiratory Fitness Later

MONDAY, Feb. 10, 2020 (HealthDay News) — Higher birth weight for births at-term are associated with greater cardiorespiratory fitness (CRF) in young adulthood regardless of body mass index, according to a study published online Jan. 31 in the Journal of the American Heart Association.

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Single Dose of HPV Vaccine May Cut Preinvasive Cervical Disease

MONDAY, Feb. 10, 2020 (HealthDay News) — Receipt of one, two, or three doses of the human papillomavirus (HPV) vaccine among females aged 15 to 19 years is associated with reduced incidence of preinvasive cervical disease at five years compared to that seen in unvaccinated females, according to a study published online Feb. 10 in Cancer.

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Baby Carriers Recalled Because Infant Can Fall Out

FRIDAY, Feb. 7, 2020 (HealthDay News) — About 14,000 Infantino soft infant and toddler carriers have been recalled because their buckles can break and put children at risk for falling, the U.S. Consumer Product Safety Commission says.

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Hexavalent Vaccine Included in Vaccines for Children Program

FRIDAY, Feb. 7, 2020 (HealthDay News) — The hexavalent combined diphtheria and tetanus toxoids and acellular pertussis (DTaP) adsorbed, inactivated poliovirus (IPV), Haemophilus influenza type b (Hib) conjugate (meningococcal protein conjugate), and hepatitis B (HepB; recombinant) vaccine (DTaP-IPV-Hib-HepB) has been included in the federal Vaccines for Children program, according to research published in the Feb. 7 issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.

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Prenatal Tobacco Exposure May Raise Risk for Pediatric Psoriasis

FRIDAY, Feb. 7, 2020 (HealthDay News) — Prenatal tobacco exposure is associated with an increased risk for pediatric psoriasis, according to a study published online Jan. 20 in the Journal of the American Academy of Dermatology.

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Screening for T1DM in Children May Help Reduce Morbidity

FRIDAY, Feb. 7, 2020 (HealthDay News) — A public health screening for islet autoantibodies demonstrated prevalence of 0.31 percent among children aged 2 to 5 years, according to a study published in the Jan. 28 issue of the Journal of the American Medical Association.

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Infant Sleep Locations Often Do Not Align With Recommendations

FRIDAY, Feb. 7, 2020 (HealthDay News) — Fewer than half of mothers practice and intend to practice recommended infant sleep location practices of room sharing without bed sharing, according to a study published online Feb. 7 in Pediatrics.

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Number of Nurse Practitioners More Than Doubled 2010 to 2017

FRIDAY, Feb. 7, 2020 (HealthDay News) — From 2010 to 2017, there was a substantial increase in the number of nurse practitioners in the United States, with a corresponding reduction in the size of the registered nurse workforce, according to a report published in the February issue of Health Affairs.

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Recommended Immunization Schedule for Children, Teens Updated

THURSDAY, Feb. 6, 2020 (HealthDay News) — Changes to the recommended immunization schedule for children and adolescents are presented in a report published in the Feb. 7 issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report and a policy statement published online Feb. 4 in Pediatrics.

ACIP Recommended Immunization Schedule
AAP Policy Statement

Experts Say U.S. Flavored E-Cigarette Products Ban Will Have Little Effect

THURSDAY, Feb. 6, 2020 (HealthDay News) — The U.S. ban on certain flavored e-cigarette products that takes effect Thursday will do little to stem teens’ use of nicotine, experts say.

NBC News Article

Recommendations Developed for Management of Complex ADHD

THURSDAY, Feb. 6, 2020 (HealthDay News) — In a Society for Developmental and Behavioral Pediatrics Clinical Practice Guideline, published online Jan. 30 in the Journal of Developmental and Behavioral Pediatrics, recommendations are presented for the management of complex attention-deficit/hyperactivity disorder (ADHD) in childhood.

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Reference Pricing Linked to Lower Prices Paid by Employers

THURSDAY, Feb. 6, 2020 (HealthDay News) — Reference prices are associated with lower prices paid by employers and lower cost sharing by employees, according to a study published online Feb. 5 in JAMA Network Open.

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Prenatal Vitamin D Does Not Reduce Asthma, Wheeze at Age 6

WEDNESDAY, Feb. 5, 2020 (HealthDay News) — Among children at risk for asthma, prenatal vitamin D supplementation does not affect the incidence of asthma or recurrent wheeze at age 6, according to a study published in the Feb. 6 issue of the New England Journal of Medicine.

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Many Antibiotic Rx Filled Without Infection-Related Diagnosis

TUESDAY, Feb. 4, 2020 (HealthDay News) — Large proportions of antibiotic prescriptions for Medicaid patients are filled without evidence of infection-related diagnoses or clinician visits, according to a report published in the February issue of Health Affairs.

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Bumetanide Promising for Reducing Autism Symptoms

TUESDAY, Feb. 4, 2020 (HealthDay News) — Bumetanide seems effective for improving symptoms of autism spectrum disorder (ASD) in young children, according to a study published online Jan. 27 in Translational Psychiatry.

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Atypical Sleep Tied to Language Skills in Neurodevelopmental Disorders

TUESDAY, Feb. 4, 2020 (HealthDay News) — In children with fragile X syndrome (FXS), Down syndrome (DS), and Williams syndrome (WS), disrupted sleep may adversely affect language development, according to a study published in the February issue of Research in Developmental Disabilities.

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Cigarette Use Down, E-Cigarette Use Up Among Teens

MONDAY, Feb. 3, 2020 (HealthDay News) — Cigarette use is dropping among teens, but electronic cigarette use is on the rise, according to a study published online Feb. 3 in Pediatrics.

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Longer Screen Time at Age 2 to 3 Affects Movement Behaviors

MONDAY, Feb. 3, 2020 (HealthDay News) — Longer screen viewing time among children aged 2 to 3 years is associated with less time engaged in physical activity and more sedentary time at age 5.5 years, according to a study published online Jan. 28 in The Lancet Child & Adolescent Health.

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Whether HPV Vaccination Will Prevent Cervical Cancer Unclear

MONDAY, Feb. 3, 2020 (HealthDay News) — Methodological problems and study limitations for trials of the human papillomavirus (HPV) vaccine create uncertainty about its ability to prevent cervical cancer in the long term, according to a review published online Jan. 21 in the Journal of the Royal Society of Medicine.

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Mothers With Autism Face Higher Rates of Postpartum Depression

MONDAY, Feb. 3, 2020 (HealthDay News) — Mothers with autism face unique challenges, and the stigma of being autistic can further exacerbate communication issues, according to a study published online Jan. 6 in Molecular Autism.

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