Home Diabetes and Endocrinology February 2018 Briefing – Diabetes & Endocrinology

February 2018 Briefing – Diabetes & Endocrinology

Here are what the editors at HealthDay consider to be the most important developments in Diabetes & Endocrinology for February 2018. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

Increased Adiposity Measures Affect MI Risk More in Women

WEDNESDAY, Feb. 28, 2018 (HealthDay News) — Increases in waist circumference and waist-to-hip ratio are associated with a greater excess risk of myocardial infarction (MI) in women than men, according to a study published online Feb. 28 in the Journal of the American Heart Association.

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Sleeve Gastrectomy Linked to Improved Glycemia in Mice

WEDNESDAY, Feb. 28, 2018 (HealthDay News) — Sleeve gastrectomy (SG) is associated with an improvement in glycemia, via increased insulin sensitivity, according to a study published online Feb. 23 in Diabetes.

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Early Studies Often Show Exaggerated Treatment Effect

TUESDAY, Feb. 27, 2018 (HealthDay News) — Trials to evaluate drugs or devices used to treat chronic medical conditions that are published early in the chain of evidence often show an exaggerated treatment effect compared with subsequent trials, according to research published online Feb. 21 in the Mayo Clinical Proceedings.

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Treatment Effect of Fenofibrate Varies in Patients With T2DM

TUESDAY, Feb. 27, 2018 (HealthDay News) — For individual patients with type 2 diabetes mellitus (T2DM), the effect of fenofibrate treatment varies and is larger in patients with dyslipidemia, according to a study published online Feb. 22 in Diabetes Care.

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CABG May Be Best for Patients With DM, LV Dysfunction

TUESDAY, Feb. 27, 2018 (HealthDay News) — Coronary artery bypass grafting (CABG) is associated with a significant reduction in major adverse cardiac and cerebrovascular events and mortality compared with percutaneous coronary intervention (PCI) among patients with diabetes mellitus (DM), multivessel coronary artery disease (CAD), and left ventricular dysfunction (LVD), according to a study published in the Feb. 27 issue of the Journal of the American College of Cardiology.

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Sleeve Gastrectomy Tied to Drop in GDM, Excessive Fetal Growth

TUESDAY, Feb. 27, 2018 (HealthDay News) — Laparoscopic sleeve gastrectomy is associated with a lower rate of gestational diabetes mellitus and excessive fetal growth, according to a study published online Feb. 5 in Obstetrics & Gynecology.

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Understanding Rx Nonadherence Can Improve Adherence

MONDAY, Feb. 26, 2018 (HealthDay News) — Understanding nonadherence in patients and encouraging a change in attitude toward patients and their medication can improve medication adherence, according to a report published by the American Medical Association (AMA).

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Recommendations for Optimizing Hidden Curriculum in Medicine

MONDAY, Feb. 26, 2018 (HealthDay News) — In a position paper published online Feb. 27 in the Annals of Internal Medicine, the American College of Physicians (ACP) presents recommendations for optimizing clinical learning environments by fostering a positive hidden curriculum in medicine.

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No Link Found for Metformin or Statins and Ovarian Cancer

MONDAY, Feb. 26, 2018 (HealthDay News) — In women with type 2 diabetes, no evidence was found of an association between the use of metformin or statins and the incidence of ovarian cancer, according to a study published online Feb. 7 in BJOG: An International Journal of Obstetrics and Gynaecology.

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No Recent Decrease in Prevalence of Obesity Among Children

MONDAY, Feb. 26, 2018 (HealthDay News) — The prevalence of obesity seems not to be decreasing for children aged 2 to 19 years, according to a study published online Feb. 22 in Pediatrics.

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Vegetarian, Med Diets Similarly Effective for Body Weight

MONDAY, Feb. 26, 2018 (HealthDay News) — A low-calorie lacto-ovo vegetarian diet (VD) and a low-calorie Mediterranean diet (MedD) are similarly effective for reducing body weight, body mass index, and fat mass for overweight omnivores, according to a study published online Feb. 26 in Circulation.

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Coronary Artery Dz Extent Similar in Men, Women With T1DM

MONDAY, Feb. 26, 2018 (HealthDay News) — For patients with type 1 diabetes, the extent of coronary artery disease (CAD) is similar in women and men admitted for coronary angiography, according to a study published online Feb. 20 in Diabetes Care.

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Artificial Intelligence May Help Prevent Physician Burnout

FRIDAY, Feb. 23, 2018 (HealthDay News) — Artificial intelligence (AI), in which computers can be trained to recognize patterns in large quantities of data, may be able to reduce physicians’ burdens, saving them time and energy, according to a report published in Medical Economics.

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Younger Onset of T2DM Linked to Increased Mortality Risk

FRIDAY, Feb. 23, 2018 (HealthDay News) — Younger onset of type 2 diabetes is associated with increased mortality risk, mainly due to cardiovascular disease (CVD) mortality, according to a study published online Feb. 22 in Diabetologia.

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CDC: No Change in Percentage of Uninsured in U.S. From ’16 to ’17

THURSDAY, Feb. 22, 2018 (HealthDay News) — The percentage of uninsured U.S. persons of all ages did not change significantly from 2016 to the first nine months of 2017, according to a report published online Feb. 22 by the National Center for Health Statistics.

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Worse Prognosis for Prediabetes Defined by HbA1c

THURSDAY, Feb. 22, 2018 (HealthDay News) — Prediabetes defined by hemoglobin A1c (HbA1c) is associated with worse prognosis than definition by fasting plasma glucose (FPG) or two-hour plasma glucose (2hPG), according to a study published online Feb. 16 in Diabetes Care.

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Perioperative Glucose but Not A1C Predicts Surgical Outcomes

WEDNESDAY, Feb. 21, 2018 (HealthDay News) — Perioperative glucose predicts 30-day mortality linearly in noncardiac surgical patients and nonlinearly in cardiac surgical patients, according to a study published online Feb. 13 in Diabetes Care.

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12-Month Weight Loss Doesn’t Differ With Low-Fat, Carb Diets

TUESDAY, Feb. 20, 2018 (HealthDay News) — Weight change over 12 months does not differ for a healthy low-fat (HLF) diet or a healthy low-carbohydrate (HLC) diet, according to a study published in the Feb. 20 issue of the Journal of the American Medical Association.

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USPSTF Urges Multicomponent Behavioral Interventions for Obesity

TUESDAY, Feb. 20, 2018 (HealthDay News) — The U.S Preventive Services Task Force (USPSTF) recommends that clinicians provide adults with a body mass index of 30 kg/m² or higher to intensive, multicomponent behavioral interventions. These findings form the basis of a draft recommendations statement, published online Feb. 20 by the USPSTF.

Draft Recommendation Statement
Draft Evidence Review
Comment on Recommendation

Burnout Found Prevalent Among Doctors in Single Health System

TUESDAY, Feb. 20, 2018 (HealthDay News) — Burnout is prevalent among physicians, affecting over one-third of physicians in a single health system, and is associated with health care delivery, according to a research letter published online Feb. 19 in JAMA Internal Medicine.

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Ertugliflozin Tied to Improved Glycemic Control in T2DM

TUESDAY, Feb. 20, 2018 (HealthDay News) — For adults with inadequately controlled type 2 diabetes, ertugliflozin treatment is associated with improved glycemic control over 52 weeks, according to a study published online Feb. 8 in Diabetes, Obesity and Metabolism.

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Bariatric Surgery Linked to Discontinuing Diabetes Meds

FRIDAY, Feb. 16, 2018 (HealthDay News) — Antidiabetes treatment discontinuation rates are higher for obese individuals undergoing bariatric surgery, according to a study published online Feb. 14 in JAMA Surgery.

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Rotating Night Shift Work Tied to Increased Odds of T2DM

FRIDAY, Feb. 16, 2018 (HealthDay News) — Rotating shift work which includes night shifts is associated with increased odds of type 2 diabetes, according to a study published online Feb. 12 in Diabetes Care.

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Sudden Sensorineural Hearing Loss Recovery Impacted by MetS

FRIDAY, Feb. 16, 2018 (HealthDay News) — Patients with metabolic syndrome have a lower rate of recovery from sudden sensorineural hearing loss (SSNHL) than those without, according to research published online Feb. 15 in JAMA Otolaryngology-Head & Neck Surgery.

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Patients Want Physicians to Have Greater Connectivity

THURSDAY, Feb. 15, 2018 (HealthDay News) — Most patients want greater connectivity, online tools and text messaging, as well as more time with their physicians, according to a report published in Medical Economics.

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Metformin After Induction Tx May Preserve Beta-Cell Function

THURSDAY, Feb. 15, 2018 (HealthDay News) — After induction short-term intensive insulin therapy (IIT), metformin is superior to intermittent IIT for maintaining beta-cell function and glycemic control over two years, according to a study published online Jan. 27 in Diabetes, Obesity and Metabolism.

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Greater Weight Loss With RYGB in Obese With T2DM at Three Years

WEDNESDAY, Feb. 14, 2018 (HealthDay News) — For obese adults with type 2 diabetes, Roux-en-Y gastric bypass (RYGB) surgery is associated with greater weight loss, lower hemoglobin A1c (HbA1c), and reduced cardiovascular risk compared with intensive medical diabetes and weight management (IMWM), according to a study published online Feb. 6 in Diabetes Care.

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Perfluoroalkyl Substances Linked to Greater Weight Regain

TUESDAY, Feb. 13, 2018 (HealthDay News) — Higher concentrations of perfluoroalkyl substances (PFASs) are associated with greater weight regain in a diet-induced weight-loss setting, according to a study published online Feb. 13 in PLOS Medicine.

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Four Best Practices Outlined to Prevent Health Care Cyberattacks

TUESDAY, Feb. 13, 2018 (HealthDay News) — Four best practices outlined that can help prevent health care cyberattacks, which increased from 2016 to 2017, according to a report published in Managed Healthcare Executive.

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Eating Slower Tied to Lower Obesity Risk in Type 2 Diabetes

TUESDAY, Feb. 13, 2018 (HealthDay News) — Eating speed can affect changes in obesity, body mass index (BMI), and waist circumference in patients with type 2 diabetes, according to a study published online Feb. 12 in BMJ Open.

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EHRs Not Sufficient to Ensure Success in Value-Based Care

MONDAY, Feb. 12, 2018 (HealthDay News) — Electronic health records (EHRs) are not sufficient to ensure success in value-based care, according to an article published in Medical Economics.

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Mortality Up in Diabetes With Low eGFR, No Albuminuria

MONDAY, Feb. 12, 2018 (HealthDay News) — Among U.S. adults with diabetes, albumin-to-creatinine ratio (ACR) values are decreasing, but mortality rates are increasing among those with ACR <30 mg/g and low estimated glomerular filtration rates (eGFRs), according to a study published online Feb. 7 in Diabetes Care.

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Top Consumer Concerns Reported About Physicians

FRIDAY, Feb. 9, 2018 (HealthDay News) — Health care consumers have four major concerns regarding their physicians, according to a report published by Managed Healthcare Executive.

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Diabetes Signs May Be Present 20 Years Before Diagnosis

FRIDAY, Feb. 9, 2018 (HealthDay News) — Risk of developing type 2 diabetes (T2D) is associated with subtle elevations of glucose and lipids more than 20 years before diagnosis, according to a study published online Feb. 5 in Diabetes, Obesity and Metabolism.

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Prenatal, Early Life Fructose Intake Associated With Asthma

FRIDAY, Feb. 9, 2018 (HealthDay News) — Maternal prenatal and early childhood intake of sugar-sweetened beverages and fructose is associated with current asthma in midchildhood, regardless of adiposity, according to a study published in the Annals of the American Thoracic Society.

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Poll: Personal Beliefs Shouldn’t Allow Doctors to Refuse to Treat

THURSDAY, Feb. 8, 2018 (HealthDay News) — Most people do not believe that professionals including health care providers should be allowed to refuse to provide services based on their conscience or beliefs, according to a recent HealthDay/The Harris Poll.

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School Program in U.K. Shows No Significant Impact on Child BMI

THURSDAY, Feb. 8, 2018 (HealthDay News) — A focused school-based healthy lifestyle program intervention does not have a significant impact on body mass index (BMI) z score after 15 or 30 months, according to a study published online Feb. 7 in The BMJ.

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ER Visit Rate 92 Per 1,000 for Diabetes Patients 45 and Older

THURSDAY, Feb. 8, 2018 (HealthDay News) — In 2015, the rate of diabetes-related visits to the emergency department was 92 per 1,000 persons for those aged 45 and older, according to a February data brief published by the U.S. Centers for Disease Control and Prevention’s National Center for Health Statistics.

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Expenditures Rising for Treating Obesity-Related Illness in U.S.

WEDNESDAY, Feb. 7, 2018 (HealthDay News) — The amount of U.S. health care resources devoted to treating obesity-related illness in U.S. adults rose 29 percent from 2001 to 2015, according to a review published in the January issue of Clinical Chemistry.

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Humanities Exposure Positively Impacts Medical Students

MONDAY, Feb. 5, 2018 (HealthDay News) — Exposure to the humanities correlates with less burnout and higher levels of positive personal qualities among medical students, according to a study published online Jan. 29 in the Journal of General Internal Medicine.

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Health Care Use Down in Diabetes Patients With High Deductibles

MONDAY, Feb. 5, 2018 (HealthDay News) — Overall, patients who switch to high-deductible health plans (HDHPs) have a decrease in health care utilization, though high-severity emergency department visit expenditures and hospitalization days increase in members from low-income neighborhoods, according to a study published online Jan. 30 in Diabetes Care.

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Factors Identified That Impact Physicians IT Adoption

FRIDAY, Feb. 2, 2018 (HealthDay News) — Physicians have considerable concerns about the efficacy and evidence base of health information technology (IT), according to a report published by the American Medical Association (AMA).

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Persistent DME More Likely With Bevacizumab Treatment

FRIDAY, Feb. 2, 2018 (HealthDay News) — For patients with diabetic macular edema (DME), persistence is more likely with bevacizumab than with aflibercept or ranibizumab, according to a study published online Feb. 1 in JAMA Ophthalmology.

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Parental Type 1 Diabetes May Increase Offspring Risk for ADHD

FRIDAY, Feb. 2, 2018 (HealthDay News) — Children whose parents have type 1 diabetes (T1D) have a higher risk of being diagnosed with attention-deficit/hyperactivity disorder (ADHD), according to a study published online Jan. 26 in Diabetes Care.

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Mortality Risk Similar for Career Versus Limited NFL Participation

FRIDAY, Feb. 2, 2018 (HealthDay News) — Career participation in professional American football seems not to be associated with an increased risk of all-cause mortality compared with limited participation, according to a study published online Feb. 1 in the Journal of the American Medical Association.

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Chronic Disease Major Risk Factor for Cancer, Cancer Mortality

FRIDAY, Feb. 2, 2018 (HealthDay News) — Chronic disease is associated with a substantial proportion of the risk of incident cancer and cancer mortality, according to a study published online Jan. 31 in The BMJ.

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Medicaid Expansion Cuts Out-of-Pocket Spending

THURSDAY, Feb. 1, 2018 (HealthDay News) — States that expanded Medicaid cut the probability of non-elderly near-poor adults being uninsured and lowered average out-of-pocket spending, according to a study published online Jan. 24 in Health Affairs.

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