Home Cardiology December 2016 Briefing – Cardiology

December 2016 Briefing – Cardiology

Here are what the editors at HealthDay consider to be the most important developments in Cardiology for December 2016. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

Low Dose Protocol Cuts Patient Exposure to Radiation During PCI

FRIDAY, Dec. 30, 2016 (HealthDay News) — A lose dose protocol (LDP) can reduce patient radiation exposure during percutaneous coronary intervention (PCI), according to a study published in the Jan. 15 issue of The American Journal of Cardiology.

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Low Vitamin D Linked to Incident Frailty in Older Women

FRIDAY, Dec. 30, 2016 (HealthDay News) — For older women, low vitamin D is associated with incident frailty, according to a study published online Dec. 23 in the Journal of the American Geriatrics Society.

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Female Gender Predictor of All-Cause Mortality After PCI

THURSDAY, Dec. 29, 2016 (HealthDay News) — Female gender is an independent predictor of all-cause mortality after percutaneous coronary intervention (PCI), according to a study published in the Jan. 15 issue of The American Journal of Cardiology.

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Weight Gain Worsens Post-Discharge Prognosis in Acute HF

THURSDAY, Dec. 29, 2016 (HealthDay News) — For patients with acute heart failure (AHF) who experience minimal weight loss or weight gain, increasing body weight is associated with worse post-discharge prognosis, according to research published in the Jan. 1 issue of JACC: Heart Failure.

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Phase I Trial Shows Promise for Cimaglermin in Heart Failure

WEDNESDAY, Dec. 28, 2016 (HealthDay News) — The recombinant growth factor, cimaglermin alfa, may enhance cardiac function in left ventricular systolic dysfunction (LVSD), according to a study published in the Dec. 1 issue of JACC: Basic to Translational Science.

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Penalties Under ACA Tied to Drop in Medicare Readmission Rates

WEDNESDAY, Dec. 28, 2016 (HealthDay News) — Passage of the Medicare Hospital Readmissions Reduction Program (HRRP) under the Affordable Care Act is associated with a more rapid decrease in 30-day risk-standardized readmission rates (RSRRs), according to a study published online Dec. 27 in the Annals of Internal Medicine.

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Postprandial Hyperglycemia Linked to CVD Incidence in T2DM

WEDNESDAY, Dec. 28, 2016 (HealthDay News) — For patients with type 2 diabetes, postprandial hyperglycemia is associated with incidence of cardiovascular disease (CVD) and all-cause mortality, independently of the mean glycated hemoglobin (HbA1c) level, according to a study published online Dec. 15 in the Journal of Diabetes Investigation.

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Personal Health Care Spending Continues to Soar in the U.S.

TUESDAY, Dec. 27, 2016 (HealthDay News) — From 1996 to 2013 there were considerable increases in personal health care spending in the United States, with the highest amounts for diabetes, ischemic heart disease, and low back and neck pain, according to a study published in the Dec. 27 issue of the Journal of the American Medical Association.

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More Years Lost for Whites Versus South Asians, Blacks With T2DM

TUESDAY, Dec. 27, 2016 (HealthDay News) — Whites with type 2 diabetes have more life years lost than South Asians or blacks, according to a study published online Dec. 20 in Diabetes Care.

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Unrecognized Heart Attacks Tied to Higher Pain Tolerance

TUESDAY, Dec. 27, 2016 (HealthDay News) — Patients who experience unrecognized myocardial infarction (MI) have reduced pain sensitivity compared to those who experience recognized MI, according to a study published online Dec. 21 in the Journal of the American Heart Association.

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Heart-Related Deaths Up at Xmas Even in Southern Hemisphere

FRIDAY, Dec. 23, 2016 (HealthDay News) — The Christmas holiday effect, showing elevated cardiovascular mortality over the Christmas holiday period, also occurs in the Southern Hemisphere, according to a study published online Dec. 22 in the Journal of the American Heart Association.

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Personal Life Choices Still Differ for Male, Female Cardiologists

THURSDAY, Dec. 22, 2016 (HealthDay News) — For cardiologists, personal life choices still differ for men and women, although men are now more likely to indicate that their family responsibilities have a negative impact on career, according to a study published online Dec. 21 in the Journal of the American College of Cardiology.

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Iron Deficiency Tied to Worse Response, Remodeling After CRT

THURSDAY, Dec. 22, 2016 (HealthDay News) — For patients undergoing cardiac resynchronization therapy (CRT), iron deficiency is prevalent and is associated with clinical response and reverse cardiac remodeling, according to a study published in the Jan. 1 issue of The American Journal of Cardiology.

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Pooled Cohort Equations Predict Myocardial Infarction Risk in HIV

WEDNESDAY, Dec. 21, 2016 (HealthDay News) — For adults with HIV, the Pooled Cohort Equations discriminate myocardial infarction (MI) risk, with no improvement in model performance with addition of HIV-specific factors, according to a study published online Dec. 21 in JAMA Cardiology.

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Peripartum Aortic Dissection Risk Factors Examined in Marfan Sx

WEDNESDAY, Dec. 21, 2016 (HealthDay News) — Pregnant patients with Marfan syndrome, particularly those with a dilating aortic root, are at high risk of aortic dissection during and following pregnancy, according to a study published in the Jan. 1 issue of The American Journal of Cardiology.

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Health Care Provider Burnout Negatively Affects Quality, Safety

TUESDAY, Dec. 20, 2016 (HealthDay News) — Health care provider burnout is negatively associated with quality and safety of health care, according to a meta-analysis published recently in the Journal of General Internal Medicine.

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Guidance on Dietary Sugar Intake Based on Low-Quality Evidence

TUESDAY, Dec. 20, 2016 (HealthDay News) — Guidelines on dietary sugar intake are of poor quality, and the supporting evidence is of low quality, according to research published online Dec. 20 in the Annals of Internal Medicine.

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DEA Announces Critical Changes in Registration Renewal Process

MONDAY, Dec. 19, 2016 (HealthDay News) — The Drug Enforcement Administration (DEA) has announced critical changes in its registration renewal process, according to a report published by the American Academy of Family Physicians.

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Noncardiovascular Cause of Death More Common in CHD Patients

MONDAY, Dec. 19, 2016 (HealthDay News) — For patients with coronary heart disease (CHD), mortality is more often due to noncardiovascular causes, according to a study published in the Jan. 1 issue of The American Journal of Cardiology.

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CTA Can Diagnose Partially Obstructed IVC in Budd-Chiari

FRIDAY, Dec. 16, 2016 (HealthDay News) — For patients with Budd-Chiari syndrome (BCS), computed tomographic angiography (CTA) has high diagnostic accuracy for partially obstructed inferior vena cava (IVC), according to a study published online Nov. 29 in the Journal of Gastroenterology and Hepatology.

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No Long-Term Increase in Exercise Levels for Pokémon Go

FRIDAY, Dec. 16, 2016 (HealthDay News) — Pokémon Go provided a slight, short-term boost to adults’ physical activity levels, but it didn’t last, according to a study published in the Christmas issue of The BMJ.

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Ischemic Stroke Risk Up for Eight Weeks After PCI

FRIDAY, Dec. 16, 2016 (HealthDay News) — The risk of ischemic stroke is highest during the first two days after percutaneous coronary intervention (PCI), and decreases gradually, but stays elevated for eight weeks, according to a study published in the Jan. 1 issue of The American Journal of Cardiology.

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Smartphone-Based Study of Cardiovascular Health Feasible

THURSDAY, Dec. 15, 2016 (HealthDay News) — Smartphones could assist cardiac research by giving instant, accurate insight into the physical activity of people using them, according to a study published online Dec. 14 in JAMA Cardiology.

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Stroke, A-Fib Recurrence Low at One Year After AF Ablation

WEDNESDAY, Dec. 14, 2016 (HealthDay News) — Stroke and atrial fibrillation (AF) recurrence are low one year after AF ablation, according to a study published online Dec. 9 in the Journal of Cardiovascular Electrophysiology.

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Outcomes-Based Pricing Suggested for New, Costly Drugs

WEDNESDAY, Dec. 14, 2016 (HealthDay News) — Outcomes-based pricing for novel and expensive biopharmaceuticals is supported in an Ideas and Opinions piece published online Dec. 13 in the Annals of Internal Medicine.

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Catheter Ablation of A-Fib Linked to More Strokes in Elderly

TUESDAY, Dec. 13, 2016 (HealthDay News) — Catheter ablation (CA) of atrial fibrillation (AF) is associated with more strokes in patients who are at least 75 years old but is not associated with other complications, according to a study published online Dec. 7 in the Journal of Cardiovascular Electrophysiology.

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Risk of Ischemic, Hemorrhagic Stroke Up With Type 1 Diabetes

TUESDAY, Dec. 13, 2016 (HealthDay News) — The risks of ischemic and hemorrhagic stroke are increased with type 1 diabetes, with incrementally increasing risks with increasing hemoglobin A1c (HbA1c), according to a study published in the November issue of the Journal of Internal Medicine.

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β-Blockers May Not Be Appropriate for Dementia Patients

TUESDAY, Dec. 13, 2016 (HealthDay News) — β-blockers may not be the medicine of choice for nursing home residents with dementia, according to a study published online Dec. 12 in JAMA Internal Medicine.

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Effect of Statins on Alzheimer’s May Depend on Gender, Race

MONDAY, Dec. 12, 2016 (HealthDay News) — Effectiveness of statin use in Alzheimer’s prevention may depend on the specific statin, and the gender and race or ethnicity of the patient, according to a study published online Dec. 12 in JAMA Neurology.

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Suicide Risk Up for Patients With Acute Coronary Syndrome

THURSDAY, Dec. 8, 2016 (HealthDay News) — Patients with acute coronary syndrome (ACS) may face a higher-than-normal risk of suicide, according to a study published online Dec. 7 in the Journal of the American Heart Association.

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Even Moderate, Regular Alcohol Consumption Could Cause A-Fib

THURSDAY, Dec. 8, 2016 (HealthDay News) — Regularly drinking even small amounts of alcohol may increase the risk of atrial fibrillation, according to a study published in the Dec. 13 issue of the Journal of the American College of Cardiology.

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Timely Epinephrine Increases Cardiac Arrest Survival

THURSDAY, Dec. 8, 2016 (HealthDay News) — Cardiac arrest patients who receive epinephrine within five minutes are more likely to survive than those who don’t receive the drug within that time frame, according to findings published online Dec. 1 in Circulation.

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Heart Rate Recovery Could Predict Mortality in Older Adults

THURSDAY, Dec. 8, 2016 (HealthDay News) — Orthostatic heart rate recovery (HRR) predicts mortality in adults aged 50 and older, according to findings published online recently in Circulation Research.

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Readings Taken in Clinic May Underestimate Ambulatory BP

WEDNESDAY, Dec. 7, 2016 (HealthDay News) — Ambulatory blood pressure may be a better indicator of health risks than clinic blood pressure, according to a new report published online Dec. 6 in Circulation.

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Prevalence of Disability 2.7 Percent at U.S. Medical Schools

WEDNESDAY, Dec. 7, 2016 (HealthDay News) — The prevalence of disability is 2.7 percent among medical students at U.S. allopathic medical schools, according to a research letter published in the Dec. 6 issue of the Journal of the American Medical Association, a theme issue of medical education.

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Learning Interventions Can Improve Med Student Well-Being

WEDNESDAY, Dec. 7, 2016 (HealthDay News) — Specific learning interventions may improve emotional well-being among medical students, according to a review published in the Dec. 6 issue of the Journal of the American Medical Association, a theme issue on medical education.

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High Lipoprotein(a) Predicts Cardiac Events in DM With PCI

WEDNESDAY, Dec. 7, 2016 (HealthDay News) — For patients with diabetes mellitus (DM) undergoing percutaneous coronary intervention (PCI), high lipoprotein(a) (Lp[a]) levels are associated with advanced cardiac events, according to a study published in the Dec. 15 issue of The American Journal of Cardiology.

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Patient Mortality Up With End-of-Rotation Team Transition

TUESDAY, Dec. 6, 2016 (HealthDay News) — Hospitalized patients who are handed off by their original medical team to a new set of caregivers may ultimately face a higher risk of early mortality, according to research published in the Dec. 6 issue of the Journal of the American Medical Association, a theme issue on medical education.

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Depression, Suicide Ideation Prevalent in Medical Students

TUESDAY, Dec. 6, 2016 (HealthDay News) — The prevalences of depression or depressive symptoms and suicide ideation are 27.2 and 11.1 percent, respectively, among medical students, according to a review published in the Dec. 6 issue of the Journal of the American Medical Association, a theme issue on medical education.

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Erectile Dysfunction Tied to Subclinical Myocardial Injury

TUESDAY, Dec. 6, 2016 (HealthDay News) — Erectile dysfunction is tied to higher circulating concentrations of high-sensitivity cardiac troponin I (hs-cTnI), indicating subclinical myocardial injury, according to a study published in the Dec. 15 issue of The American Journal of Cardiology.

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Low Thromboembolism Risk for Contraceptive Use in Diabetes

TUESDAY, Dec. 6, 2016 (HealthDay News) — For women with diabetes who are using hormonal contraception, the absolute risk of thromboembolism is low, with the lowest rates seen with use of intrauterine and subdermal contraceptives, according to a study published online Nov. 29 in Diabetes Care.

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DASH Diet Reduces Serum Uric Acid in Prehypertension

MONDAY, Dec. 5, 2016 (HealthDay News) — Among adults with prehypertension or stage I hypertension, following the Dietary Approaches to Stop Hypertension (DASH) diet lowers serum uric acid (UA), according to a study published online Nov. 28 in Arthritis & Rheumatology.

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Similar Effects for PCSK9, HMGCR Variant-Mediated Lower LDL

FRIDAY, Dec. 2, 2016 (HealthDay News) — Variants in genes encoding proprotein convertase subtilisin-kexin type 9 (PCSK9) and 3-hydroxy-3-methylglutarylcoenzyme A reductase (HMGCR) are associated with almost equivalent effects on the risk of cardiovascular events and diabetes per unit decrease in low-density lipoprotein (LDL) cholesterol level, according to a study published in the Dec. 1 issue of the New England Journal of Medicine.

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Meds Don’t Cut Trastuzumab-Tied Left Ventricular Remodeling

FRIDAY, Dec. 2, 2016 (HealthDay News) — For patients with human epidermal growth factor receptor 2-overexpressing (HER2-positive) early breast cancer, perindopril and bisoprolol do not prevent trastuzumab-mediated left ventricular remodeling, according to a study published online Nov. 28 in the Journal of Clinical Oncology.

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Acute, Noncardiac Mortality Risk Up for CA Patients With STEMI

FRIDAY, Dec. 2, 2016 (HealthDay News) — Cancer survivors with ST-segment elevation myocardial infarction (STEMI) have increased acute in-hospital and long-term noncardiac mortality risk but no increased acute or long-term cardiac mortality risk with guideline-recommended cardiac care, according to a study published in the December issue of the Mayo Clinic Proceedings.

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Dabigatran May Be Better Than Warfarin After Bleeding Episode

FRIDAY, Dec. 2, 2016 (HealthDay News) — Dabigatran is less likely than warfarin to cause recurrent bleeding in atrial fibrillation patients who have experienced a major bleeding event, according to a study published online Dec. 1 in Stroke.

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Increased VTE Risk for Men Starting Testosterone Therapy

THURSDAY, Dec. 1, 2016 (HealthDay News) — Starting testosterone treatment is associated with an increased risk of venous thromboembolism (VTE), peaking within six months and declining thereafter, according to a study published online Nov. 30 in The BMJ.

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AND: Vegetarian Diet a Healthy, Environmentally Sound Choice

THURSDAY, Dec. 1, 2016 (HealthDay News) — Vegetarian diets are healthy for people of all ages, as well as the environment, according to a new position statement from the Academy of Nutrition and Dietetics (AND). The report has been published in the December issue of the Journal of the Academy of Nutrition and Dietetics.

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CDC: Fewer U.S. Families Struggling to Pay Medical Bills

THURSDAY, Dec. 1, 2016 (HealthDay News) — The number of people in families having problems paying medical bills fell by nearly 13 million from 2011 through the first six months of 2016, according to a report published by the U.S. Centers for Disease Control and Prevention’s National Center for Health Statistics (NCHS).

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Participation in Specific Sports Tied to Significant Health Benefits

THURSDAY, Dec. 1, 2016 (HealthDay News) — Participation in specific sports may have significant benefits for public health, according to a study published online Nov. 28 in the British Journal of Sports Medicine.

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Study Supports Smoking Cessation for Smokers of Any Age

THURSDAY, Dec. 1, 2016 (HealthDay News) — Age at smoking initiation and cessation continue to be important predictors of mortality in U.S. adults over age 70, according to a study published online Nov. 29 in the American Journal of Preventive Medicine.

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