Here are what the editors at HealthDay consider to be the most important developments in Internal Medicine for August 2017. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.
No Link for Cardiovascular Meds Use, Cognitive Impairment
THURSDAY, Aug. 31, 2017 (HealthDay News) — For older adults, there is no association between cardiovascular medication use and cognitive impairment, according to a study published online Aug. 24 in Cardiovascular Therapeutics.
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CDC: 60 Percent of America’s Single Men Report Using Condoms
THURSDAY, Aug. 31, 2017 (HealthDay News) — About six in 10 sexually active single men in the United States are taking responsibility for birth control, according to an August data brief published by the U.S. Centers for Disease Control and Prevention’s National Center for Health Statistics.
Minimal Evidence for Electronic Communication Guidelines
THURSDAY, Aug. 31, 2017 (HealthDay News) — Minimal evidence is available for guidelines for electronic communication between patients and providers, according to research published online Aug. 28 in the Journal of the American Medical Informatics Association.
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Stem Cell Factor Tied to Reduced Risk of Cardiac Events, Death
THURSDAY, Aug. 31, 2017 (HealthDay News) — High levels of stem cell factor (SCF) are associated with reduced risk of mortality and cardiovascular events, according to a study published online Aug. 26 in the Journal of Internal Medicine.
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Transvenous Pacemaker Complications Common, Costly
THURSDAY, Aug. 31, 2017 (HealthDay News) — The incidence of complications for single- and dual-chamber transvenous pacemakers (TVPs) is considerable, reaching about 15 and 16 percent, respectively, by three years, with high associated costs, according to research published online Aug. 30 in JACC: Clinical Electrophysiology.
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Spousal Caregiver Well-Being Tied to Recipient Health Expenses
THURSDAY, Aug. 31, 2017 (HealthDay News) — Poor spousal caregiver well-being is associated with increased care recipient expenditures and emergency department use, according to a study published online Aug. 24 in the Journal of the American Geriatrics Society.
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Prophylaxis Linked to Improved Function, HRQoL in Hemophilia
THURSDAY, Aug. 31, 2017 (HealthDay News) — For adults with severe hemophilia and pre-existing joint disease, prophylaxis is associated with improved function, quality of life, activity, and pain, according to a study published online Aug. 24 in the Journal of Thrombosis and Haemostasis.
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CPR Less Likely for Cardiac Arrests in Black Neighborhoods
THURSDAY, Aug. 31, 2017 (HealthDay News) — In cases of cardiac arrest, the racial make-up of the neighborhood may determine the likelihood of receiving cardiopulmonary resuscitation (CPR) from a passer-by or having access to a public defibrillator, according to a study published online Aug. 30 in JAMA Cardiology.
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More Evidence Links Epstein-Barr Virus to MS Risk
THURSDAY, Aug. 31, 2017 (HealthDay News) — Infection with Epstein-Barr virus (EBV) or cytomegalovirus may up the risk for multiple sclerosis (MS), and the link isn’t limited to whites, according to a study published online Aug. 30 in Neurology.
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Local Allergic Rhinitis Often Progresses Over Time
THURSDAY, Aug. 31, 2017 (HealthDay News) — Patients with local allergic rhinitis (LAR) show worsening of rhinitis, greater tendency toward development of asthma, and impairment of quality of life after 10 years, but have a similar rate of development of allergic rhinitis with systemic atopy as controls, according to research published online Aug. 22 in Allergy.
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Retinal Emboli Linked to Cardiac Risk Factors, Kidney Disease
THURSDAY, Aug. 31, 2017 (HealthDay News) — Retinal emboli are associated with conventional cardiovascular risk factors, stroke, and chronic kidney disease, according to a study published online Aug. 24 in JAMA Ophthalmology.
FDA Approves Vabomere for Complicated UTIs
WEDNESDAY, Aug. 30, 2017 (HealthDay News) — The intravenous antibiotic Vabomere (meropenem and vaborbactam) has been approved by the U.S. Food and Drug Administration to treat certain complicated urinary tract infections, including pyelonephritis.
Sedentary Time a ‘Potent Risk Factor’ for Mobility Loss
WEDNESDAY, Aug. 30, 2017 (HealthDay News) — Excessive sitting, especially while watching television, poses a significant health hazard to older Americans, according to a study published online Aug. 30 in the Journal of Gerontology: Medical Sciences.
Proactive Approach Encouraged for Online Patient Reviews
WEDNESDAY, Aug. 30, 2017 (HealthDay News) — Most patients are using online reviews as a first step to finding a new doctor, with 65 percent forming an opinion from reading one to six reviews, according to a report published in Medical Economics.
Insurer Aetna’s Envelopes Revealed Customers’ HIV Status
WEDNESDAY, Aug. 30, 2017 (HealthDay News) — Customers of health insurance giant Aetna in many states were sent mail with envelopes that clearly revealed their HIV status, say the Legal Action Center and AIDS Law Project of Pennsylvania.
Most Melanomas Don’t Start As Existing Moles
WEDNESDAY, Aug. 30, 2017 (HealthDay News) — The majority of melanomas arise from new lesions rather than existing moles, according to a review published online Aug. 29 in the Journal of the American Academy of Dermatology.
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Review Links Sleep-Disordered Breathing, Cognitive Impairment
WEDNESDAY, Aug. 30, 2017 (HealthDay News) — Sleep-disordered breathing (SDB) is associated with increased likelihood of cognitive impairment, according to a review published online Aug. 28 in JAMA Neurology.
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Risk of Needing Nursing Home Care Is Rising
TUESDAY, Aug. 29, 2017 (HealthDay News) — More than half of Americans will require nursing home care at some point in their lives, according to a report published online Aug. 28 in the Proceedings of the National Academy of Sciences.
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Younger Adults, Especially Men, Lag in HTN Treatment, Control
TUESDAY, Aug. 29, 2017 (HealthDay News) — Despite recent improvements in hypertension awareness, treatment, and control overall, all three remain worse in adults aged 18 to 39, according to research published online Aug. 28 in Hypertension.
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Options Available for Estrogen Depletion After Breast Cancer
TUESDAY, Aug. 29, 2017 (HealthDay News) — Many non-hormone options and therapies are available for the treatment of estrogen-depletion symptoms in breast cancer survivors, and individualized treatment is important, according to a review published online Aug. 2 in the Journal of Clinical Endocrinology & Metabolism.
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Platelet-Rich Plasma Effective for Chronic Venous Leg Ulcers
TUESDAY, Aug. 29, 2017 (HealthDay News) — For patients with chronic venous leg ulcers, autologous platelet-rich plasma (PRP) is safe and effective, with highly significant improvement in ulcer size compared to conventional treatment, according to a study published online Aug. 19 in the Journal of Cosmetic Dermatology.
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FDA Cites ‘Significant Deviations’ at Florida Stem Cell Clinic
TUESDAY, Aug. 29, 2017 (HealthDay News) — A Florida stem cell clinic has received a warning letter from the U.S. Food and Drug Administration about what the agency describes as serious problems that could pose health risks to patients.
Gender-Specific High-Risk ‘Window’ Seen in Alzheimer’s
TUESDAY, Aug. 29, 2017 (HealthDay News) — Women with a genetic predisposition for Alzheimer’s disease face a 10-year window — between ages 65 and 75 — when they have far greater chances of developing the disease than men with similar genetic risks, according to a study published online Aug. 28 in JAMA Neurology.
Clinicians Urged to Heighten Alert for Perinatal Suicide Risk
TUESDAY, Aug. 29, 2017 (HealthDay News) — Suicide is a leading cause of death among pregnant and recently pregnant women, according to a study published online Aug. 28 in CMAJ, the journal of the Canadian Medical Association.
Androgen-Deprivation Therapy May Carry Cardiovascular Risks
MONDAY, Aug. 28, 2017 (HealthDay News) — Use of androgen-deprivation therapy (ADT) may increase the risk of certain cardiovascular conditions in men with prostate cancer, according to a study published online Aug. 24 in the British Journal of Cancer.
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Increases in IgE, Eosinophils, Mast Cells Can ID IgG4-RD
MONDAY, Aug. 28, 2017 (HealthDay News) — Most patients with immunoglobulin G subclass 4-related disease (IgG4-RD) have increased levels of IgE, eosinophils, and mast cells, according to research published in the September issue of Clinical Gastroenterology and Hepatology.
Less Than Half of Seniors With A-Fib Receive Anticoagulants
MONDAY, Aug. 28, 2017 (HealthDay News) — Less than 45 percent of older adults with atrial fibrillation (AF) admitted to the hospital are prescribed an anticoagulant, according to a study published online Aug. 21 in the Journal of the American Geriatrics Society.
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Tidal CO2 Prognostic for Chronic Thromboembolic Pulmonary HTN
MONDAY, Aug. 28, 2017 (HealthDay News) — End-tidal carbon dioxide (ETCO2) levels are prognostic for patients with chronic thromboembolic pulmonary hypertension (CTEPH), according to a letter to the editor published online Aug. 14 in the Annals of the American Thoracic Society.
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Community Consumption Comprises Most Antibacterial Use
MONDAY, Aug. 28, 2017 (HealthDay News) — Community antibacterial consumption comprises about 85 to 95 percent of total antibacterial consumption, according to a study published online Aug. 18 in the Journal of Clinical Pharmacy and Therapeutics.
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Cycling Crash Deaths Rising in the United States
FRIDAY, Aug. 25, 2017 (HealthDay News) — Bicyclist deaths on U.S. roadways are up significantly, and men — not children — are commonly the victims, a new report finds.
Opioids Often Prescribed Unnecessarily for Migraine
FRIDAY, Aug. 25, 2017 (HealthDay News) — Too many patients with migraines are prescribed opioids, while too few may be getting recommended medications, according to research published recently in Cephalalgia.
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ART Era Has Changed Secondary Cancers After Kaposi Sarcoma
FRIDAY, Aug. 25, 2017 (HealthDay News) — There has been a significant decline in the risk of secondary cancers after Kaposi sarcoma (KS) in the era of highly-active antiretroviral therapy (HAART), according to a study published online Aug. 24 in JAMA Oncology.
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Lithium in Drinking Water Linked to Dementia Incidence
FRIDAY, Aug. 25, 2017 (HealthDay News) — Lithium in drinking water is associated with the incidence of dementia in a nonlinear pattern, according to a study published online Aug. 23 in JAMA Psychiatry.
Insufficient Sleep May Lead to Increased Risk-Taking Behavior
FRIDAY, Aug. 25, 2017 (HealthDay News) — Chronic sleep restriction may lead to risk-seeking behavior, according to a study published online Aug. 21 in the Annals of Neurology.
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Only One-Third of Heart Attack Patients Enter Cardiac Rehab
FRIDAY, Aug. 25, 2017 (HealthDay News) — Only one in three heart attack survivors in the United States attends outpatient cardiac rehabilitation, according to research published in the Aug. 25 issue of the U.S. Centers for Disease Control and Prevention’s Morbidity and Mortality Weekly Report.
More Evidence Evolocumab Exceeds Cost-Effectiveness
FRIDAY, Aug. 25, 2017 (HealthDay News) — At its current price, the addition of evolocumab to standard therapy in patients with atherosclerotic cardiovascular disease generally exceeds accepted cost-effectiveness thresholds, according to a study published online Aug. 23 in JAMA Cardiology.
Asthma Tied to Later Inflammatory Bowel Disease
FRIDAY, Aug. 25, 2017 (HealthDay News) — Asthma is associated with subsequent development of inflammatory bowel disease (IBD), according to a study published in the September issue of Clinical Gastroenterology and Hepatology.
Meth Use Tied to Higher Risk of Stroke in Younger People
THURSDAY, Aug. 24, 2017 (HealthDay News) — Younger adults who use methamphetamine appear to be at greater risk for stroke, particularly hemorrhagic stroke, according to research published online Aug. 23 in the Journal of Neurology Neurosurgery & Psychiatry.
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Hearing Loss Contributing to Patient-Doctor Miscommunication
THURSDAY, Aug. 24, 2017 (HealthDay News) — Many seniors may not hear everything their doctors tell them, and that could raise the risk of medical errors, according to a research letter published online Aug. 24 in JAMA Otolaryngology-Head & Neck Surgery.
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Cardiopulmonary Exercise Testing Prognostic in Aortic Stenosis
THURSDAY, Aug. 24, 2017 (HealthDay News) — For patients judged as symptomatic or questionably symptomatic for aortic stenosis, an initially conservative management strategy results in good prognosis if cardiopulmonary exercise testing (CPET) does not indicate significant hemodynamic compromise, according to a study published in the Sept. 1 issue of The American Journal of Cardiology.
Increased Risk of MI, Stroke for Patients With Hip Fracture
THURSDAY, Aug. 24, 2017 (HealthDay News) — Patients with hip fracture have an increased risk of myocardial infarction (MI) and stroke, according to a study published online Aug. 21 in the Journal of Bone and Mineral Research.
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Google Search for ‘Depression’ Now to Provide Screening Test
THURSDAY, Aug. 24, 2017 (HealthDay News) — Web search giant Google is partnering with the National Alliance on Mental Illness (NAMI) to make depression screening a part of a search for ‘depression’ on the site.
Intensive BP Treatment Appears Safe, Well Tolerated
THURSDAY, Aug. 24, 2017 (HealthDay News) — For patients at increased risk of cardiovascular disease, intensive blood pressure control may be just as safe as standard treatment, and is likely cost-effective, according to research published in the Aug. 24 issue of the New England Journal of Medicine.
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Less REM May Indicate Higher Dementia Risk in Seniors
THURSDAY, Aug. 24, 2017 (HealthDay News) — Seniors who spend less time each night in rapid eye movement (REM) sleep may be more likely to develop dementia as they age, according to a study published online Aug. 23 in Neurology.
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No Increase in Acute Kidney Injury Risk for SGLT2 Users
THURSDAY, Aug. 24, 2017 (HealthDay News) — The risk of acute kidney injury (AKI) is not increased for new sodium-glucose cotransporter-2 (SGLT2) inhibitor users, according to a study published online Aug. 21 in Diabetes Care.
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Patient Beliefs May Explain High Rate of Medicine Intake
THURSDAY, Aug. 24, 2017 (HealthDay News) — Subjective norms and attitudes toward medicine consumption predict the intention and expectation to consume medicines, according to a study published online Aug. 19 in the Journal of Clinical Pharmacy and Therapeutics.
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Day-Supply of Opioid Rx Factor in Likelihood of Long-Term Use
WEDNESDAY, Aug. 23, 2017 (HealthDay News) — The days supplied is far more important than the dosage level or even the type of pain being treated in risk of opioid use disorder following opioid prescription, according to a study published recently in The Journal of Pain.
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Collaborative Communication Could Improve HTN Rx Adherence
WEDNESDAY, Aug. 23, 2017 (HealthDay News) — Health care providers can help boost patient adherence to antihypertensive medications by communicating more collaboratively with patients, and including discussion of socioeconomic challenges, according to a study published online Aug. 22 in Circulation: Cardiovascular Quality and Outcomes.
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Vitamin B6, B12 Supplements May Up Risk of Lung Cancer in Men
WEDNESDAY, Aug. 23, 2017 (HealthDay News) — Men, and especially male smokers, appear to be more likely to develop lung cancer if they take high doses of vitamins B6 and B12, according to a study published online Aug. 22 in the Journal of Clinical Oncology.
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Cost-Effectiveness of PCSK9 Inhibitors Called Into Question
WEDNESDAY, Aug. 23, 2017 (HealthDay News) — The costs of PCSK9 inhibitors would have to be 71 percent lower to be deemed cost-effective, according to a research letter published in the Aug. 22/29 issue of the Journal of the American Medical Association.
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Demand for Liver Transplant for NASH Set to Continue Rising
WEDNESDAY, Aug. 23, 2017 (HealthDay News) — Given population obesity trends, the increase in the demand for liver transplantation (LT) for nonalcoholic steatohepatitis (NASH) noted since 2000 is expected to continue, according to a study published online Aug. 17 in Hepatology.
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Once-Yearly Counseling Tied to More Physical Activity in T2DM
WEDNESDAY, Aug. 23, 2017 (HealthDay News) — Theoretical and practical once-yearly counseling for three years is associated with increased physical activity (PA) and reduced sedentary (SED) time in patients with type 2 diabetes, according to a study published online Aug. 18 in Diabetes Care.
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Tablet Use Encourages Patients to Explore Diabetes Risk
WEDNESDAY, Aug. 23, 2017 (HealthDay News) — The multispecialty San Bernardino Medical Group has replaced magazines with digital devices in waiting rooms, which can help patients learn about their risk of diabetes and take preventive action, according to a report published by the American Medical Association (AMA).
Nurse-, System-Related Factors Analyzed in Wrong-Patient Events
WEDNESDAY, Aug. 23, 2017 (HealthDay News) — Greater focus is needed on correct identification processes in order to prevent wrong-patient medication administration incidents, and system supports for nurses are critical, according to a study published online Aug. 17 in the Journal of Clinical Nursing.
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Oral Corticosteroids No Benefit for LRI in Non-Asthmatic Adults
TUESDAY, Aug. 22, 2017 (HealthDay News) — For adults without asthma, with acute cough and at least one lower respiratory tract symptom, prednisolone does not reduce cough duration or severity, according to a study published in the Aug. 22/29 issue of the Journal of the American Medical Association.
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Even Overdose Doesn’t Stop Opioid Prescribing
TUESDAY, Aug. 22, 2017 (HealthDay News) — After treatment for an opioid overdose, many Medicaid patients continue to receive prescriptions for them and few are prescribed anti-addiction medications after hospital discharge, according to a research letter published in the Aug. 22/29 issue of the Journal of the American Medical Association.
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NT-ProBNP-Guided Treatment No Benefit in High-Risk HFrEF
TUESDAY, Aug. 22, 2017 (HealthDay News) — For high-risk patients with heart failure and reduced ejection fraction (HFrEF), an amino-terminal pro-B-type natriuretic peptide (NT-proBNP)-guided treatment strategy does not improve clinical outcomes versus usual care, according to a study published in the Aug. 22/29 issue of the Journal of the American Medical Association.
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In T2D, Glycemic Control Up With Continuous Glucose Monitoring
TUESDAY, Aug. 22, 2017 (HealthDay News) — Adults with type 2 diabetes receiving multiple daily insulin injections randomized to continuous glucose monitoring (CGM) have improved glycemic control versus usual care, according to a study published online Aug. 22 in the Annals of Internal Medicine.
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Occult Cancer Found in ~5 Percent With Unprovoked VTE
TUESDAY, Aug. 22, 2017 (HealthDay News) — About one in 20 patients with unprovoked venous thromboembolism (VTE) have occult cancer detected within one year, according to a review published online Aug. 22 in the Annals of Internal Medicine.
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Maraviroc-Containing HIV PrEP Regimens Safe, Well Tolerated
TUESDAY, Aug. 22, 2017 (HealthDay News) — Maraviroc (MVC)-containing HIV pre-exposure prophylaxis (PrEP) regimens are well tolerated for preventing HIV infection in uninfected women, according to a study published online Aug. 22 in the Annals of Internal Medicine.
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Few Smokers Hospitalized With CHD Get Smoking Cessation Meds
TUESDAY, Aug. 22, 2017 (HealthDay News) — Few smokers hospitalized for coronary heart disease (CHD) receive smoking cessation pharmacotherapy (SCP), according to a research letter published online Aug. 21 in JAMA Internal Medicine.
Lower SBP Target for Blacks May Benefit Cognitive Function
TUESDAY, Aug. 22, 2017 (HealthDay News) — For seniors and particularly blacks with hypertension, lowering systolic blood pressure to 120 mm Hg or lower may help prevent cognitive decline, according to a report published online Aug. 21 in JAMA Neurology.
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Flexible Sigmoidoscopy Screening Reduces Mortality
MONDAY, Aug. 21, 2017 (HealthDay News) — Screening with flexible sigmoidoscopy reduces all-cause mortality, according to a research letter published online Aug. 22 in the Annals of Internal Medicine.
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Hours Worked Impacted by Kids for Female, Not Male Doctors
MONDAY, Aug. 21, 2017 (HealthDay News) — For women, but not men, in dual-physician couples, weekly hours worked are lower for those with versus those without children, according to a research letter published online Aug. 21 in JAMA Internal Medicine.
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Once-Daily Triple-Tx Improves Lung Function, HRQoL in COPD
MONDAY, Aug. 21, 2017 (HealthDay News) — For patients with chronic obstructive pulmonary disease (COPD), once-daily single-inhaler triple therapy is better for lung function and health-related quality of life than inhaled corticosteroid (ICS)/long-acting β2-agonist (LABA) therapy, according to a study published in the Aug. 15 issue of the American Journal of Respiratory and Critical Care Medicine.
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Clinical Feature Model Predicts Colitis Outcomes
MONDAY, Aug. 21, 2017 (HealthDay News) — Clinical features, including response at day seven of hospitalization for the index episode of acute severe colitis (ASC), can predict both colectomy and steroid dependence with reasonable accuracy, according to a study published online Aug. 12 in the Journal of Gastroenterology and Hepatology.
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Secure Messaging Linked to Better Diabetes Management
MONDAY, Aug. 21, 2017 (HealthDay News) — For patients with diabetes, use of secure messaging for medical advice is associated with better diabetes management, according to a study published online Aug. 14 in Diabetes Care.
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Link for Sedentary Time, Mortality Varies With Frailty Level
MONDAY, Aug. 21, 2017 (HealthDay News) — The association between sedentary time and mortality varies with level of frailty among adults aged 50 years and older, according to a study published online Aug. 21 in CMAJ, the journal of the Canadian Medical Association.
Higher Odds of Infection With Reduced Kidney Function
FRIDAY, Aug. 18, 2017 (HealthDay News) — As kidney function declines, infection risk rises, according to a study published online Aug. 17 in the Clinical Journal of the American Society of Nephrology.
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Radioiodine Therapy for Thyroid Cancer Doesn’t Up Stroke Risk
FRIDAY, Aug. 18, 2017 (HealthDay News) — Radioiodine (I-131) therapy for thyroid cancer is not associated with increased risk of stroke, according to a study published online Aug. 16 in Head & Neck.
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Procalcitonin Testing Not Impacting Antibiotic Rx for COPD
FRIDAY, Aug. 18, 2017 (HealthDay News) — Hospital adoption of procalcitonin (PCT) testing has had little impact on antibiotic prescribing for chronic obstructive pulmonary disease (COPD) exacerbations, according to a study published online Aug. 10 in the Annals of the American Thoracic Society.
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Physical Activity Predicts Disability in Older Adults
FRIDAY, Aug. 18, 2017 (HealthDay News) — Accelerometer-measured physical activity (PA) levels are strongly associated with major mobility disability (MMD) and persistent MMD (PMMD) events in older adults with limited mobility, according to a study published online Aug. 11 in the Journal of the American Geriatrics Society.
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Candida Antigen Safe, Effective for Treating Common Warts
FRIDAY, Aug. 18, 2017 (HealthDay News) — Candida antigen is a promising, effective, and safe immunotherapeutic treatment for common warts, according to a study published online Aug. 8 in the International Journal of Dermatology.
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Studies Often Fail to Include Info on T2DM Medication Adherence
FRIDAY, Aug. 18, 2017 (HealthDay News) — Studies often fail to include information on outcomes by medication adherence in type 2 diabetes, according to research published online Aug. 11 in Diabetes Care.
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Oral Contraceptive Use Linked to Lower Rheumatoid Arthritis Risk
FRIDAY, Aug. 18, 2017 (HealthDay News) — Oral contraceptive (OC) use is associated with reduced risk of rheumatoid arthritis (RA), according to research published online Aug. 17 in the Annals of Rheumatic Diseases.
Visual Dysfunction Tied to Poor Cognitive Function in Seniors
FRIDAY, Aug. 18, 2017 (HealthDay News) — Visual dysfunction at baseline is associated with poor cognitive function among older U.S. adults, according to a study published online Aug. 17 in JAMA Ophthalmology.
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Most Ulcerative Colitis Patients Do Not Achieve Target Remission
FRIDAY, Aug. 18, 2017 (HealthDay News) — Most patients with ulcerative colitis (UC) do not achieve the ‘Treat to Target’ (T2T) end point of composite clinical and endoscopic remission, according to research published online Aug. 14 in the Journal of Gastroenterology and Hepatology.
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Psychosocial Intervention App Feasible in Serious Mental Illness
FRIDAY, Aug. 18, 2017 (HealthDay News) — A psychosocial self-management intervention can be adapted for smartphone application and used by adults with serious mental illness, according to a study published in the August issue of the American Journal of Geriatric Psychiatry.
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Moderate, Severe OSA Linked to Elevated Blood Coagulability
FRIDAY, Aug. 18, 2017 (HealthDay News) — Moderate and severe obstructive sleep apnea (OSA) are associated with elevated blood coagulability markers, according to a study published online Aug. 17 in JAMA Otolaryngology-Head & Neck Surgery.
Telehealth Feasible for Parkinson’s Care
FRIDAY, Aug. 18, 2017 (HealthDay News) — Virtual house calls by neurologists may be of great interest to and provide substantial convenience for patients with Parkinson’s disease, according to a study published online Aug. 16 in Neurology.
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Worse Survival Seen for Alternative Vs Usual Cancer Rx
FRIDAY, Aug. 18, 2017 (HealthDay News) — Patients who choose alternative medicine over traditional cancer treatments for curable cancers have a higher risk of dying early, according to research published online Aug. 10 in the Journal of the National Cancer Institute.
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Online Nursing Education Can Up Patient Use of VTE Prophylaxis
THURSDAY, Aug. 17, 2017 (HealthDay News) — Online training for nurses has been found to increase hospital patients’ use of venous thromboembolism (VTE) prophylaxis, according to a study published online Aug. 16 in PLOS ONE.
Increasing Physical Activity, Function Can Decrease Fall Fears
THURSDAY, Aug. 17, 2017 (HealthDay News) — Enhancing physical activity level and function can decrease the fear of falling among elderly patients, according to a study published online Aug. 9 in the Journal of Clinical Nursing.
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Intensive Blood Pressure Tx Aids Those With Prediabetes
THURSDAY, Aug. 17, 2017 (HealthDay News) — The beneficial effects of intensive systolic blood pressure (SBP) treatment are similar among those with prediabetes and fasting normoglycemia, according to a study published online Aug. 9 in Diabetes Care.
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Study Highlights Readmit Factors Post Atrial Flutter Ablation
THURSDAY, Aug. 17, 2017 (HealthDay News) — Recognition of factors associated with early readmission for patients after atrial flutter (AFL) ablation is necessary for reducing costs and improving quality of life, according to a study published online Aug. 11 in the Journal of Cardiovascular Electrophysiology.
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Evolocumab Doesn’t Affect Cognition When Added to Statins
THURSDAY, Aug. 17, 2017 (HealthDay News) — There is no significant difference in cognitive function for patients treated with evolocumab or placebo added to statin therapy, according to a study published in the Aug. 17 issue of the New England Journal of Medicine.
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Global Disease Burden of COPD, Asthma Quantified
THURSDAY, Aug. 17, 2017 (HealthDay News) — In 2015, there were more deaths worldwide due to chronic obstructive pulmonary disease (COPD) than asthma, according to a study published online Aug. 16 in The Lancet Respiratory Medicine.
Families Shoulder Majority of Costs Related to Dementia Care
THURSDAY, Aug. 17, 2017 (HealthDay News) — Lifetime costs of care are substantially increased for individuals with dementia, according to a study published online Aug. 17 in the Journal of the American Geriatrics Society.
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Dietary Energy Density May Up Risk of Obesity-Linked Cancers
THURSDAY, Aug. 17, 2017 (HealthDay News) — Higher dietary energy density (DED; the ratio of energy intake to food weight) is associated with increased risk of obesity-related cancers among normal-weight women, according to a study published online Aug. 17 in the Journal of the Academy of Nutrition and Dietetics.
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Opioid Rx Frequently Issued for Nonspecific, Spinal Conditions
THURSDAY, Aug. 17, 2017 (HealthDay News) — Within a cohort of patients insured through TRICARE, the most common diagnosis associated with initial opioid prescription is other ill-defined conditions, according to a research letter published online Aug. 16 in JAMA Surgery.
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Risk Assessment Differs for Doctors, Heart Failure Patients
WEDNESDAY, Aug. 16, 2017 (HealthDay News) — Physicians consider the majority of ambulatory patients with advanced heart failure on medical therapy to be at high risk for transplant, left ventricular assist device (LVAD) placement, and death, although patients rarely consider themselves at high risk, according to a study published online Aug. 16 in JACC: Heart Failure.
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Frequency, Degree of Pubic Hair Grooming Linked to Injury Risk
WEDNESDAY, Aug. 16, 2017 (HealthDay News) — The frequency and degree of pubic hair grooming is associated with the risk of grooming-related injury and high-frequency injury, according to a study published online Aug. 16 in JAMA Dermatology.
FDA: Potential Contamination in Some Liquid Pharma Products
WEDNESDAY, Aug. 16, 2017 (HealthDay News) — The U.S. Food and Drug Administration has announced a recall of numerous liquid pharmaceutical products because of possible bacterial contamination that could cause severe infections in vulnerable patients.
Geriatric Trauma Outcome Score Estimates Unfavorable Discharge
WEDNESDAY, Aug. 16, 2017 (HealthDay News) — The geriatric trauma outcome score II (GTOS II) prognostic calculator can estimate the probability of unfavorable discharge in injured elders, according to a study published online Aug. 14 in the Journal of the American Geriatrics Society.
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Antidepressants Used by 12.7 Percent of Those Age ≥12 in U.S.
WEDNESDAY, Aug. 16, 2017 (HealthDay News) — Antidepressant use is common among U.S. individuals aged 12 years and older, with non-Hispanic whites more likely to take antidepressants than other racial/ethnic groups, according to an August data brief published by the U.S. Centers for Disease Control and Prevention’s National Center for Health Statistics (NCHS).
Single-Color PCR Detects Cancer Mutations From Circulating DNA
WEDNESDAY, Aug. 16, 2017 (HealthDay News) — A single-color digital polymerase chain reaction (PCR) assay can detect cancer mutations directly from circulating DNA from patients, according to research published online Aug. 14 in the Journal of Molecular Diagnostics.
’07 to ’14 Saw Drop in Proportion Needing Dialysis After TAVI
WEDNESDAY, Aug. 16, 2017 (HealthDay News) — From 2007 to 2014 there was a decrease in the proportion of patients needing dialysis after transcatheter aortic valve implantation (TAVI), according to a study published online Aug. 2 in JACC: Cardiovascular Interventions.
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Perceived Social Support Lower for Cancer Caregivers Vs Patients
WEDNESDAY, Aug. 16, 2017 (HealthDay News) — A sense of coherence (SOC) is associated with cancer patients’ acceptance of their illness, according to a study published Aug. 9 in the Journal of Clinical Nursing.
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Plasma Amino Acids Up in Non-Alcoholic Fatty Liver Disease
WEDNESDAY, Aug. 16, 2017 (HealthDay News) — In non-alcoholic fatty liver disease (NAFLD), increased plasma amino acid (AA) concentrations are observed, according to a study published online Aug. 12 in Hepatology.
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Lifestyle Intervention Only Offers Modest Benefit in Type 2 Diabetes
TUESDAY, Aug. 15, 2017 (HealthDay News) — For adults with type 2 diabetes diagnosed for less than 10 years, a lifestyle intervention resulted in a beneficial change in glycemic control that did not reach the criterion for equivalence, according to a study published in the Aug. 15 issue of the Journal of the American Medical Association.
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Studies Used for FDA Approval of Device Changes Often Low Quality
TUESDAY, Aug. 15, 2017 (HealthDay News) — Many studies used to support U.S. Food and Drug Administration approval of high-risk medical device modifications are not controlled; and efficacy of drugs granted accelerated approval is often confirmed three years after approval, according to two studies published in the Aug. 15 issue of the Journal of the American Medical Association.
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Specialist Access No Better With Adoption of Access Standards
TUESDAY, Aug. 15, 2017 (HealthDay News) — Adoption of specialty access standards does not improve access to specialists, according to a study published online Aug. 14 in JAMA Internal Medicine.
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High Platelet Reactivity Tied to Ischemic, Bleeding Outcomes
TUESDAY, Aug. 15, 2017 (HealthDay News) — There is a strong relationship between high on-clopidogrel platelet reactivity and two-year ischemic and bleeding outcomes after drug-eluting stent implantation, according to a study published online Aug. 2 in JACC: Cardiovascular Interventions.
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Most Patients With Care Plan Die in Chosen Location
TUESDAY, Aug. 15, 2017 (HealthDay News) — Most individuals with a Coordinate My Care (CMC) plan die in their chosen location, according to a research letter published online Aug. 15 in the Annals of Internal Medicine.
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Diverse Spectrum of Neurologic Syndromes Seen With Zika
TUESDAY, Aug. 15, 2017 (HealthDay News) — Zika virus (ZIKV) infection is associated with increased incidence of neurological syndromes, according to a study published online Aug. 14 in JAMA Neurology.
Exposure to Particulate Matter Linked to Metabolic Alterations
TUESDAY, Aug. 15, 2017 (HealthDay News) — Exposure to particulate matter (PM) with aerodynamic diameters ≤2.5 µm is associated with metabolic alterations, according to a study published online Aug. 14 in Circulation.
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‘On the Move’ Group Exercise Program Aids Walking in Elderly
TUESDAY, Aug. 15, 2017 (HealthDay News) — The “On the Move” group exercise program is more effective at improving mobility in the elderly, compared to seated, usual-care exercise programs, according to a study published online Aug. 14 in JAMA Internal Medicine.
Intraindividual Variability in Reaction Time Tied to Mortality
TUESDAY, Aug. 15, 2017 (HealthDay News) — Intraindividual variability of reaction time (IIVRT) is independently associated with mortality, according to a study published online Aug. 9 in PLOS ONE.
Caregivers Have a Worse View of Cancer Patients’ Functional Status
TUESDAY, Aug. 15, 2017 (HealthDay News) — Compared to patients themselves, caregivers rate older cancer patients as having poorer physical function, poorer mental health, and more social support, according to a study published online Aug. 14 in The Oncologist.
Review: Cannabis May Alleviate Neuropathic Pain
MONDAY, Aug. 14, 2017 (HealthDay News) — Cannabis may alleviate neuropathic pain, but is not associated with benefit for adults with posttraumatic stress disorder (PTSD), according to two reviews published online Aug. 15 in the Annals of Internal Medicine.
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Short-Term Risk of Arterial Embolism Up in Cancer Patients
MONDAY, Aug. 14, 2017 (HealthDay News) — The risk of arterial thromboembolism is increased in the short term among patients with incident cancer, according to a study published in the Aug. 22 issue of the Journal of the American College of Cardiology.
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All-Cause, CVD Mortality Down With Light, Moderate Drinking
MONDAY, Aug. 14, 2017 (HealthDay News) — All-cause and cardiovascular disease (CVD) mortality are reduced for U.S. adults with light and moderate alcohol intake, according to a study published in the Aug. 22 issue of the Journal of the American College of Cardiology.
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Apathy Tied to Mortality in Nursing Home Patients
MONDAY, Aug. 14, 2017 (HealthDay News) — Apathy is associated with mortality in nursing home patients, according to a study published online Aug. 9 in the Journal of the American Geriatrics Society.
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Smoking During Pregnancy Up Among Women With Depression
MONDAY, Aug. 14, 2017 (HealthDay News) — Over the past decade, smoking during pregnancy has increased significantly among women experiencing a major depressive episode (MDE), according to a study published in the Oct. 1 issue of Drug and Alcohol Dependence.
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Variation in Participation in Diabetes Self-Management Class
MONDAY, Aug. 14, 2017 (HealthDay News) — There is considerable variation in nonparticipation in diabetes self-management classes, according to a study published online Aug. 3 in the U.S. Centers for Disease Control and Prevention’s Preventing Chronic Disease.
Review: Killed Whole-Cell Oral Cholera Vaccine Efficacious
MONDAY, Aug. 14, 2017 (HealthDay News) — Two doses of killed whole-cell oral cholera vaccine (kOCV) are efficacious for protecting against cholera for at least two years after vaccination, according to a review published online July 17 in The Lancet Infectious Diseases.
Statin Use Among Nursing Home Residents Varies Significantly
MONDAY, Aug. 14, 2017 (HealthDay News) — Statin prescribing is considerable among nursing home residents, with significant variation in prescribing seen across physicians, according to a study published online Aug. 9 in the Journal of the American Geriatrics Society.
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ICU Admissions for Opioid Overdose Up From 2009 to 2015
MONDAY, Aug. 14, 2017 (HealthDay News) — From 2009 to 2015 there was an increase in opioid overdose admissions requiring intensive care, as well as in associated mortality, according to a study published online Aug. 11 in the Annals of the American Thoracic Society.
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Hyperglycemia May Cause Caries but Not Periodontal Disease
MONDAY, Aug. 14, 2017 (HealthDay News) — For rodents with diabetes, periodontal inflammation may be derived from dental caries rather than periodontal disease (PD), according to a study published online Aug. 9 in Diabetes.
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Rates of Active, Current Epilepsy in U.S. Adults Rising
MONDAY, Aug. 14, 2017 (HealthDay News) — In 2015, an estimated 1.2 percent of the U.S. population reported active or current epilepsy, according to research published in the Aug. 11 issue of the U.S. Centers for Disease Control and Prevention’s Morbidity and Mortality Weekly Report.
Most Common Arrhythmia: Intra-Atrial Re-Entrant Tachycardia
MONDAY, Aug. 14, 2017 (HealthDay News) — For patients with congenital heart disease and atrial arrhythmias, the most common presenting arrhythmia is intra-atrial re-entrant tachycardia (IART), according to a study published in the Aug. 15 issue of the Journal of the American College of Cardiology.
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Work Exposure to Noxious Fumes May Up Rheumatoid Arthritis Risk
THURSDAY, Aug. 10, 2017 (HealthDay News) — Certain occupations related to potential noxious airborne agents are associated with increased risk of rheumatoid arthritis (RA) in workers, according to a study published online Aug. 10 in Arthritis Care & Research.
Team-Based Online Game May Improve Glycemic Control in T2D
THURSDAY, Aug. 10, 2017 (HealthDay News) — Sustained and meaningful improvements in hemoglobin A1c (HbA1c) are seen with participation in a diabetes self-management education (DSME) game, according to a study published online Aug. 8 in Diabetes Care.
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Increase in Alcohol Use, High-Risk Drinking in U.S. Adults
THURSDAY, Aug. 10, 2017 (HealthDay News) — From 2001-2002 to 2012-2013 there was an increase in alcohol use, high-risk drinking, and in the Diagnostic and Statistical Manual of Mental Disorders, 4th Edition (DSM-IV) alcohol use disorder (AUD), according to a study published online Aug. 9 in JAMA Psychiatry.
Study Quantifies Condom Use in 15- to 44-Year-Olds in 2011-15
THURSDAY, Aug. 10, 2017 (HealthDay News) — Condom use was 23.8 percent for women and 33.7 percent for men aged 15 to 44 years in 2011 to 2015, according to a study published online Aug. 10 by the National Center for Health Statistics (NCHS).
Opioid Prescription Rates Higher in Cancer Survivors
THURSDAY, Aug. 10, 2017 (HealthDay News) — Substantially higher opioid prescribing rates persist among cancer survivors, even long after attaining survivorship, according to a study published online Aug. 7 in Cancer.
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Marijuana Use May Up Risk of Hypertension-Related Mortality
THURSDAY, Aug. 10, 2017 (HealthDay News) — Marijuana increases by three-fold the risk for hypertension-related mortality, according to a study published online Aug. 9 in the European Journal of Preventive Cardiology.
Decrease Over Time in Incidence of Strokes in Men
WEDNESDAY, Aug. 9, 2017 (HealthDay News) — The incidence of all strokes decreased over time in men, but not women, with the difference driven by a decrease in ischemic stroke, according to a study published online Aug. 9 in Neurology.
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Live Attenuated Flu Vaccine Not Effective for Children in 2015-16
WEDNESDAY, Aug. 9, 2017 (HealthDay News) — During the 2015 to 2016 season, influenza vaccines reduced the risk of influenza illness, but the live attenuated vaccine was ineffective among children 2 to 17 years of age, according to a study published in the Aug. 10 issue of the New England Journal of Medicine.
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Midlife Vascular Risk Factors Tied to Increased Risk of Dementia
WEDNESDAY, Aug. 9, 2017 (HealthDay News) — Risk factors for dementia include black race, older age, and lower educational attainment, as well as midlife vascular risk factors such as smoking, diabetes, and hypertension, according to a study published online Aug. 7 in JAMA Neurology.
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Higher Risk of CVD Persists After Hospital Stay for Severe Infection
WEDNESDAY, Aug. 9, 2017 (HealthDay News) — There is an increased risk of cardiovascular disease following hospital admission for sepsis or pneumonia that persists for at least five years after the infection, according to a study published online Aug. 1 in the European Journal of Preventive Cardiology.
Colorectal Cancer Mortality Rates Down in Blacks, Up in Whites
TUESDAY, Aug. 8, 2017 (HealthDay News) — Colorectal cancer (CRC) mortality rates have decreased since 1970 in black adults (aged 20 to 54 years), but increased among white individuals, according to a research letter published in the Aug. 8 issue of the Journal of the American Medical Association.
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Blood Pressure Variability Linked to Risk of Dementia in Elderly
TUESDAY, Aug. 8, 2017 (HealthDay News) — Increased blood pressure variability is associated with a higher risk of all-cause dementia, vascular dementia (VaD), and Alzheimer’s disease (AD) in the elderly, according to a study published in the Aug. 8 issue of Circulation.
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Interactions Occur With Cannabidiol, Antiepileptic Drugs
TUESDAY, Aug. 8, 2017 (HealthDay News) — Several significant interactions can occur between cannabidiol and antiepileptic drugs, according to a study published online Aug. 6 in Epilepsia.
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Non-Specialists Can Expand Hepatitis C Treatment Access
TUESDAY, Aug. 8, 2017 (HealthDay News) — Non-specialists, including primary care providers (PCPs) and nurse practitioners (NPs), safely and effectively administer direct-acting antiviral therapy for hepatitis C virus (HCV) to patients seen in federally qualified health centers (FQHCs), according to a study published online Aug. 8 in the Annals of Internal Medicine.
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Guidance Provided for Preventing Practice Billing Errors
MONDAY, Aug. 7, 2017 (HealthDay News) — Strategies can help to prevent medical practice billing errors, according to a report published in Medical Economics.
Single Measures of Viral Load May Overestimate HIV Suppression
MONDAY, Aug. 7, 2017 (HealthDay News) — Single measures of viral load can overestimate how many individuals with HIV infection have viral suppression, according to an observation piece published online Aug. 8 in the Annals of Internal Medicine.
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Osteoporosis Meds Up BMD in Nonmetastatic Prostate Cancer
MONDAY, Aug. 7, 2017 (HealthDay News) — For men with nonmetastatic prostate cancer who are receiving androgen deprivation therapy (ADT), bisphosphonates and denosumab improve bone mineral density (BMD), according to a review published online Aug. 8 in the Annals of Internal Medicine.
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Review: Antibiotics Effectively Prevent Recurrent Cellulitis
MONDAY, Aug. 7, 2017 (HealthDay News) — Antibiotic prophylaxis can prevent recurrence of cellulitis, according to a review published online June 20 in the Cochrane Library.
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No Effect of B Vitamin on Fracture Risk in Women at High CV Risk
MONDAY, Aug. 7, 2017 (HealthDay News) — For women with preexisting cardiovascular (CV) disease or three or more coronary risk factors, daily supplementation with B vitamins and folic acid does not affect fracture risk or bone turnover, according to a study published online July 29 in the Journal of Bone and Mineral Research.
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FDA Approves Mavyret for Hepatitis C
FRIDAY, Aug. 4, 2017 (HealthDay News) — Mavyret (glecaprevir and pibrentasvir) has been approved by the U.S. Food and Drug Administration to treat adults with certain types of chronic hepatitis C virus (HCV).
Strong Religious Beliefs May Be Linked to Higher Weight
FRIDAY, Aug. 4, 2017 (HealthDay News) — There is evidence of a significant association between religious affiliation and body weight, with religiosity being significantly associated with higher body weight, according to research published online Aug. 2 in Obesity Reviews.
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Review Suggests Benefits of Aerobic Exercise in Fibromyalgia
THURSDAY, Aug. 3, 2017 (HealthDay News) — Aerobic exercise seems beneficial for patients with fibromyalgia, with improvements in health-related quality of life (HRQOL), according to a review published online June 21 in the Cochrane Library.
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Centralized Mailings Can Improve CRC Screening Adherence
THURSDAY, Aug. 3, 2017 (HealthDay News) — A centralized program which includes mailings can increase the time in compliance with colorectal cancer (CRC) screening guidelines, according to a study published online July 28 in Cancer.
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Are Clinicians Overprescribing Gabapentinoids for Pain?
WEDNESDAY, Aug. 2, 2017 (HealthDay News) — Clinicians may be overprescribing gabapentinoids, in part as a response to the opioid epidemic, according to a perspective piece published in the Aug. 3 issue of the New England Journal of Medicine.
Less Than Half of Stroke Discharges Prescribed a Statin
WEDNESDAY, Aug. 2, 2017 (HealthDay News) — Less than half of ischemic stroke patients discharged from the hospital receive a prescription for statins, according to a study published online Aug. 2 in the Journal of the American Heart Association.
Canagliflozin Delays Increase in Certain CV Biomarkers in T2DM
WEDNESDAY, Aug. 2, 2017 (HealthDay News) — For patients with type 2 diabetes mellitus (T2DM), treatment with canagliflozin delays the increase in serum N-terminal pro-B type natriuretic peptide (NT-proBNP) and high-sensitivity troponin I (hsTnI) compared with placebo, according to a study published in the Aug. 8 issue of the Journal of the American College of Cardiology.
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Review: Levetiracetam Best Monotherapy for Partial Seizures
WEDNESDAY, Aug. 2, 2017 (HealthDay News) — Levetiracetam performs better than carbamazepine and lamotrigine for individuals with partial seizures, according to a review and meta-analysis published online June 29 in the Cochrane Library.
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Revenue Exceeds Expenditures for Many ABMS Member Boards
WEDNESDAY, Aug. 2, 2017 (HealthDay News) — Overall revenue exceeds expenditures for many American Board of Medical Specialties (ABMS) member boards, according to a study published in the Aug. 1 issue of the Journal of the American Medical Association.
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Periodontal Disease History Linked to Increased Cancer Risk
TUESDAY, Aug. 1, 2017 (HealthDay News) — Among older women, periodontal disease history is associated with increased total cancer risk, and with increased risk of several specific types of cancer, according to a study published in the Aug. 1 issue of Cancer, Epidemiology, Biomarkers & Prevention.
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Methylprednisolone Ups Adverse Events in IgA Nephropathy
TUESDAY, Aug. 1, 2017 (HealthDay News) — Oral methylprednisolone is associated with increased risk of serious adverse events among patients with immunoglobulin A (IgA) nephropathy and proteinuria of greater than 1 g/day, according to a study published in the Aug. 1 issue of the Journal of the American Medical Association.
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U.S. Doctors Still Writing Too Many Opioid Prescriptions
TUESDAY, Aug. 1, 2017 (HealthDay News) — More than one out of three average Americans used a prescription opioid in 2015, despite growing concerns these medicines are promoting widespread addiction and overdose deaths, according to a study published online Aug. 1 in the Annals of Internal Medicine.
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Little Risk of Oropharyngeal Mucosal Transmission of Zika
TUESDAY, Aug. 1, 2017 (HealthDay News) — The Zika virus doesn’t appear to be transmitted through saliva, according to a study published online Aug. 1 in Nature Communications.
New Research Supports Safety of Aspirin in Heart Failure
TUESDAY, Aug. 1, 2017 (HealthDay News) — Some research has raised concerns about the safety of aspirin for heart failure patients, but a new study, published in the Aug. 1 issue of JACC: Heart Failure, appears to offer some reassurance.
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Climate Change Expected to Up Premature Deaths From Pollution
TUESDAY, Aug. 1, 2017 (HealthDay News) — Increases in air pollution caused by rising temperatures will trigger an additional 60,000 premature deaths each year around the globe by 2030, and as many as 260,000 more premature deaths annually by 2100, according to findings from a new study published online July 31 in Nature Climate Change.
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Comprehensive Initiative Has Positive Impact on Opioid Rx
TUESDAY, Aug. 1, 2017 (HealthDay News) — A comprehensive initiative, including creation of prescribing and dispensing policies, monitoring and follow-up processes, and clinical coordination through electronic health record integration, can have a positive impact on opioid prescribing, according to research published online July 14 in the Journal of Evaluation in Clinical Practice.
Higher Risk of Dementia Seen in Those Hailing From ‘Stroke Belt’
TUESDAY, Aug. 1, 2017 (HealthDay News) — Health issues for people born in high stroke mortality states (HSMSs) include a higher risk of developing dementia — even if they move elsewhere, according to research published online July 31 in JAMA Neurology.
Meta-Analysis Compares Efficacy of Therapies for Preventing TB
TUESDAY, Aug. 1, 2017 (HealthDay News) — Isoniazid monotherapy, rifampicin monotherapy, and combination therapies can be efficacious for preventing active tuberculosis (TB) among adults and children with latent TB infection (LTBI), according to research published online Aug. 1 in the Annals of Internal Medicine.
Conservative Fluid Management Benefits Black ARDS Patients
TUESDAY, Aug. 1, 2017 (HealthDay News) — For patients with acute respiratory distress syndrome (ARDS), conservative fluid management is associated with reduced mortality for non-Hispanic black, but not white, patients, according to a study published online July 14 in the Annals of the American Thoracic Society.
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