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Monthly Archives: October 2018

Selective inhibition of TYK2 with the oral agent BMS-986165 at doses of 3 mg daily and higher results in greater clearing of psoriasis versus placebo over 12 weeks

TYK2 Inhibitor Clears Psoriasis Over 12 Weeks

Findings seen in 12-week, phase 2 trial at oral doses over 3 mg daily
Minority residents describe burdens associated with race/ethnicity

Minority Residents Experience Burdens Linked to Race/Ethnicity

Residents describe daily barrage of microaggression, bias; being tasked as race/ethnicity ambassadors
Implementation of the 2017 American College of Cardiology/American Heart Association blood pressure guideline would direct initiation and intensification of antihypertensive medication treatment to adults at high risk for cardiovascular disease events

Application of Blood Pressure Guidelines Ups Treatment

Implementing ACC/AHA guideline would direct antihypertensive meds to adults at high CVD risk
An integrated plasma proteomics classifier

Integrated Classifier Identifies Benign Lung Nodules

Classifier integrates relative abundance of two plasma proteins with clinical risk prediction model
Kidney transplant patients who are preemptively wait-listed have substantially fewer years of pretransplant dialysis than transplant recipients listed after dialysis onset

Less Pre-Kidney Transplant Dialysis With Preemptive Waitlist

Preemptively listed recipients have about four fewer years of pretransplant dialysis
In critically ill patients

Mechanical Ventilation May Alter Diaphragm Muscle Fibers

This reduction in fiber length may make it more difficult to wean patients from ventilation
A bipartisan bill to fight the opioid addiction crisis in the United States has been passed by Congress. President Donald Trump said he would sign the bill into law.

Congress Passes Bill to Fight Opioid Crisis

Comprehensive bipartisan package earmarks billions of dollars to fight opioid abuse in the United States
An Arizona company has recalled more than 6.5 million pounds (2.9 million kilograms) of beef linked to a Salmonella outbreak that has sickened 57 people in 16 states. Fourteen people have been hospitalized. No deaths have been reported

AZ Company Recalls Raw Beef Products Linked to Salmonella

57 people sickened; 14 people have been hospitalized; no deaths reported to date
Industry employees are often involved in the design

Industry-Funded Trials Often Involve Employees in Studies

Many trials published in high-impact journals involve funder, academic author in study design, reporting
A reduced fetal movement care package does not reduce the risk for stillbirths

Stillbirth Reduction Strategy Unproven

Care package for reduced fetal movement does not cut stillbirths