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Monthly Archives: April 2016

HIV-positive transplant recipients and their physicians should be aware of potential interactions between fixed dose combination products used for HIV treatment and immunosuppressant metabolism

Interactions for HIV Drug Combos, Immunosuppressants

Drug interaction-induced calcineurin inhibitor nephrotoxicity described in renal transplant recipient
Neither the American College of Rheumatology nor the Systemic Lupus International Collaborating Clinics criteria distinguishes
patients with subacute cutaneous lupus erythematosus with major internal disease from those without

SLICC/ACR Criteria Don’t ID Severe Internal Disease in SCLE

Clinicians should not rely on these criteria in subacute cutaneous lupus erythematosus
Simvastatin/ezetimibe does not appear to be beneficial for severe alopecia areata in a sample of 20 patients

Simvastatin/Ezetimibe Not Beneficial in Alopecia Areata

In sample of 20 patients, most report no hair regrowth following six months of treatment
Treatment with the selective noradrenalin-reuptake-inhibitor atomoxetine is not associated with increased suicide risk compared with stimulant use in children and adolescents

Atomoxetine Use Doesn’t Up Suicide Risk in Children

No increased risk for current atomoxetine use in first- and second-line treatment of youths
For patients undergoing transcatheter mitral valve repair

Six-Minute Walk Test Predicts Mortality in TMVR Patients

For patients undergoing transcatheter mitral valve repair, highest mortality for those unable to walk
Detection of concerning symptoms after radical cystectomy can be improved by optimizing the timing and number of outpatient encounters

Optimally Timed Follow-Up Cuts Readmissions After Cystectomy

Timing, frequency of outpatient care helps identify concerning symptoms following radical cystectomy
The drug eteplirsen should not be approved for treatment of Duchenne muscular dystrophy

FDA Panel Votes Against Approval of Eteplirsen for DMD

Clinical data did not meet the agency's requirements for well controlled studies necessary for approval
Examining national data from 1999 through 2014

Severe Childhood Obesity Still on the Rise in the United States

Treatment for these 4.5 million children is urgently needed
Influenza vaccination may be more effective when people receive it in the morning than in the afternoon

Influenza Vaccination Timing Appears to Affect Efficacy

Vaccination seems to provide greater immune response in the morning than in the afternoon
Women who work rotating night shifts may face a slightly increased risk of coronary heart disease

Coronary Heart Disease Risk Up for Women Working Night Shifts

But researchers found that the effect waned after nurses stopped working odd hours