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The long-term effectiveness and harms of opioids for chronic pain are unclear

Major Risks of Long-Term Opioid Rx Deemed Dose-Dependent

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In review, serious harms of long-term therapy seemed to depend on opioid dose
Evidence is insufficient for opioid use in chronic pain

NIH: Insufficient Evidence for Opioid Use in Chronic Pain

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Insufficient evidence for every clinical decision that a provider needs to make about use of opioids