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Fewer Opioids Being Prescribed for Low Back Pain in the Emergency Department

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Opioids administered or prescribed in 35.0 and 32.5 percent of U.S. visits in 2016, respectively, compared with 24.5 and 13.5 percent in 2022

Newer Antiseizure Medications Less Likely to Be Associated With Major Malformations in Infants

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Maternal use of valproate, phenobarbital, and topiramate early in pregnancy linked to increased risk versus lamotrigine use

Oral Ondansetron Beneficial for Pediatric Gastroenteritis-Linked Vomiting

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Lower risk for moderate-to-severe gastroenteritis seen during seven days after enrollment with oral ondansetron versus placebo

ENDO: Osteoporosis Treatment Benefits Elderly Patients With Fragility Fracture

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Benefits include lower incidence of all-cause mortality, hospitalizations

Delays in HTN Diagnosis Linked to Delays in Medication Prescribing

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Increased cardiovascular risk over five years also seen in association with delayed diagnosis

Vaporized Nicotine Products More Effective Than Nicotine Replacement Therapy

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Verified six-month continuous abstinence rate 9.6 percent in NRT group and 28.4 percent in VNP group

Nocturnal Hypertension Control Improved With Bedtime Antihypertensive Dosing

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Better control of nocturnal blood pressure and improved circadian rhythm seen with bedtime versus daytime dosing

Anticholinergics Tied to Physical Performance Decline in Older Adults

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Authors say findings support guidance to avoid these medications when possible

Approved-Label Populations for New Drugs Broader Than Trial Populations

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Inconsistency seen most often in terms of patient fitness, with variance in almost all approved indications

Kerendia Approved for Heart Failure With Left Ventricular Ejection Fraction ≥40 Percent

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Patients taking Kerendia saw significant reduction in cardiovascular death and hospitalization and urgent visits for heart failure