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ADA: Ecnoglutide Yields Superior, Sustained Reduction in Body Weight

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Sustained reduction seen in body weight versus placebo for adults aged 18 to 75 with overweight or obesity, without diabetes

Quality Improvement Initiative Ups Adherence to Medical Therapy for Heart Failure

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Defect-free quadruple medication therapy significantly improved at discharge, 30 days in patients with heart failure with reduced ejection fraction

Few Adolescents With Obesity Prescribed Obesity Medications

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0.5 percent with obesity were prescribed an obesity medication in 2023; 83 percent of prescriptions received by teens with severe obesity

Finerenone + Empagliflozin Offers Greater Benefit in CKD, T2DM

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Greater reduction in urinary albumin-to-creatinine ratio seen for combination versus either agent alone

Dapagliflozin Beneficial for Improving MASH Without Worsening Fibrosis

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Dapagliflozin results in more patients with improved or resolved MASH without worsening of fibrosis, improved fibrosis without worsening of MASH

P2Y12 Inhibitor Monotherapy Beneficial for Patients Who Undergo PCI

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Risk for major adverse cardiac and cerebrovascular events lower compared with aspirin monotherapy for patients who undergo PCI and discontinue DAPT

ASCO: Durvalumab Plus FLOT Beneficial for Resectable Gastric, GE Junction Cancer

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Better event-free survival outcomes seen for durvalumab plus FLOT versus FLOT alone in phase 3 randomized trial

Initiation of HIV PrEP in Young Adults Rose in Recent Years

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PrEP dispensing and initiation have increased but PrEP persistence has decreased

ASCO: Elinzanetant Cuts Vasomotor Symptoms in Women With Breast Cancer on Endocrine Therapy

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Findings seen in women with moderate-to-severe vasomotor symptoms associated with endocrine therapy for HR-positive breast cancer

Lamivudine Improves Visual Acuity in Center-Involved Diabetic Macular Edema

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Best corrected visual acuity improved 9.8 letters with lamivudine after four weeks, decreased 1.8 letters with placebo