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Icotrokinra Beneficial for Adults, Teens With Plaque Psoriasis

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Icotronkinra results in significantly higher incidence of complete skin clearance at week 16 than placebo

GI Safety Profile Similar for Dulaglutide, Semaglutide, Tirzepatide

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No significant increase in hazard ratios seen for GI events for semaglutide versus dulaglutide, tirzepatide versus dulaglutide, tirzepatide versus semaglutide

Two HLA Class I Alleles Independently Linked to Allopurinol-Induced SCARs

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HLA-B*58:01 and HLA-A*34:02 linked to increased risk, while no HLA class II alleles were identified

Dupilumab Reduces Mucus Plug Scores With Moderate-to-Severe Asthma

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Dupilumab treatment also improved patients’ lung function

Reducing Use of Sleep Drugs Helps Older Adults Live Better

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Benefits include reduction in falls and cognitive impairment and improvements in life expectancy, quality of life

SGLT-2 Inhibitors Tied to Lower Risk for Autoimmune Rheumatic Diseases in Adults With T2D

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SGLT-2 inhibitors linked lower risk for autoimmune rheumatic diseases compared with sulfonylureas

CHEST: Nerandomilast Slows Decline in FVC in Idiopathic Pulmonary Fibrosis

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No significant difference seen in composite end point of acute exacerbation, hospitalization for respiratory cause, or death

Abemaciclib + Endocrine Therapy Improves Survival in HR-Positive, HER2-Negative Early Breast Cancer

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15.8 percent lower risk for death seen with abemaciclib-ET versus ET in intent-to-treat population

Enzalutamide + Leuprolide Boosts Overall Survival for Prostate Cancer With High Recurrence Risk

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Enzalutamide monotherapy was not superior to leuprolide alone

FDA Approves Jascayd for Idiopathic Pulmonary Fibrosis

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Twice-daily oral tablet marks first approval of idiopathic pulmonary fibrosis in more than 10 years