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Acid suppression therapy is associated with increased incidence of kidney stones and chronic kidney disease

ASN: Acid Suppression Therapy Linked to Kidney Stones, CKD

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Two studies show increased risk of kidney stones with PPI, H2 blocker use; CKD with PPI use
Cigarette smoking may decrease the effectiveness of medication taken during early stages of chronic kidney disease

ASN: Smoking May Negate Some Benefits of Rx Therapy in CKD

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Possibly because cigarette smoking causes oxidative stress
For patients with type 2 diabetes

Follow-Up Phone Calls May Boost Glycemic Control in T2DM

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No statistically significant change in hemoglobin A1c, but clinically significant change observed
Metformin seems to alter gut microbiota composition

Metformin Alters Gut Microbiota Composition in Diabetes

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Higher relative abundance of A. muciniphila, SCFA-producing microbiota for metformin-treated diabetes
Half of patients hospitalized with atrial fibrillation aren't receiving oral anticoagulants

AHA: Many A-Fib Patients Not Receiving Oral Anticoagulants

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Only 46 percent of patients with indications received OACs at discharge from hospital
Data mining can be used to discover unknown drug-drug interactions in cardiovascular medicine

Data From Clinical Registries Can ID Novel Drug Interactions

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Drug groups with known interactions rediscovered, new drug groups ID'd in warfarin-treated patients
For patients undergoing coronary angiography

Sodium Bicarbonate Prophylaxis Linked to Lower Mortality

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Lower mortality versus sodium chloride in patients undergoing coronary angiography
For patients with nonvalvular atrial fibrillation

Competing Risks Influence Warfarin, Thromboembolism Link

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Warfarin-linked reduction in VTE attenuated after accounting for competing death events
For children with complicated pneumonia

IV, Oral Antibiotics Compared for Complicated Pneumonia

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No difference in post-discharge treatment failure; more complications, adverse drug events for PICC
For African-Americans with type 2 diabetes

DECIDE Modalities Beneficial for African-Americans With T2DM

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Most robust improvements seen for Self-Study modality, including HbA1c, blood pressure, lipids