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ACS: Surgery May Follow Initial Antibiotic Therapy for Appendicitis

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At one and two years, 40 and 46 percent of patients initially receiving antibiotics underwent subsequent appendectomy

Achieving high serogroup B meningococcal vaccination coverage is recommended following university-based outbreaks of meningococcal disease caused by serogroup B

High Rates of MenB Vaccination Advised in University Outbreaks

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Estimated first-dose vaccination coverage varied from 14 to 98 percent in 10 university outbreaks
Oxford University has announced that final-stage testing of a COVID-19 vaccine it is developing with drug maker AstraZeneca will restart following a pause last week after a serious side effect showed up in a volunteer.

AstraZeneca COVID-19 Vaccine Trial Restarts

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Trial was halted after a suspected adverse reaction in a patient
Most children with special health care needs with current attention-deficit/hyperactivity disorder receive medication treatment or behavioral therapy

Three-Quarters of Children With ADHD Take Meds

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Just under one-third of children receive both meds and behavioral therapy
For patients with relapsed multiple myeloma

Cardiovascular AEs Common With Carfilzomib in Multiple Myeloma

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Patients with relapsed multiple myeloma experiencing CVAEs had inferior survival
Newborns and young infants in developing nations who have suspected severe bacterial infections can be effectively treated outside a hospital

New Guidelines Could Up Care Access for Millions in Africa

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For treating babies with possible serious bacterial infections
For patients with knee osteoarthritis

Physical Therapy, Lifestyle Advice Underused in Knee OA

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2007 to 2015 saw increase in use of NSAID prescriptions from orthopedists, primary care doctors
Drinking alcohol appears to negatively affect driving skills to a greater extent than smoking cannabis

Alcohol Use Appears to Impair Driving More Than Cannabis Use

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And combination of the two increases risks but effect isn't doubled
The U.S. Preventive Services Task Force (USPSTF) has found that current evidence is insufficient for determining the balance of benefits and harms of lipid disorder screening in children

Two Draft Statements From USPSTF Open for Comment

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Insufficient evidence for lipid screening in children; recommendation for statins varies with age, risk
A considerable proportion of antibiotics are prescribed without a documented indication

Antibiotics Often Prescribed Without Documented Indication

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Of 130.5 million prescriptions in 2015, 18 percent had no documented indication