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Patients with advanced head and neck cancer undergoing chemoradiotherapy and receiving metformin experience more side effects than patients not on metformin

More Side Effects With CRT Plus Metformin in Head, Neck Cancer

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Metformin group less likely to tolerate cisplatin, have grade ≥3 nausea/vomiting, hematologic toxicities
The rate of muscle-related adverse event reports is increased when patients and their doctors are aware that statins are being used

Nocebo Effect Reported for Statin Therapy Use

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Excess rate of muscle-related adverse event reports when patients are aware that statins being used
In a case report published online May 1 in Diabetes Care

Case Report Describes Insulin Autoimmune Syndrome

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Following treatment with rituximab, decreases seen in total insulin, anti-insulin antibody concentration
Sublingual buprenorphine is associated with shorter duration of treatment than oral morphine for infants with neonatal abstinence syndrome

PAS: Buprenorphine Beneficial in Neonatal Abstinence Syndrome

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Sublingual buprenorphine linked to shorter duration of treatment, length of hospital stay
Electronic-health-based management of oral anticoagulation therapy is associated with fewer adverse events

E-Health-Based Management of Oral Anticoagulation Tx Beneficial

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E-health-based coagulation service linked to lower frequency of adverse events
For young children with presymptomatic Wilson disease

Zinc Effective in Pediatric Presymptomatic Wilson Disease

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Initial dose of 50 mg/day of zinc was effective for children under 6 years old
Obesity and sex are differential predictors of acute remission for commonly used antidepressant medications

Obesity, Sex Predict Remission for Antidepressant Medications

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Females, but not males, with higher BMI more likely to remit, regardless of medication type
For acute coronary syndrome patients undergoing percutaneous coronary intervention and receiving clopidogrel

Ischemic Outcomes Don’t Vary With Gender in ACS Patients

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No difference by gender for ACS patients undergoing PCI receiving clopidogrel, prasugrel, or ticagrelor
For overweight and obese individuals

Cardiometabolic Disease Staging Score Quantifies Diabetes Risk

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CMDS can predict the effectiveness of weight-loss therapy for preventing diabetes in overweight/obese
A human monoclonal antibody inhibitor of insulin-like growth factor I receptor

Teprotumumab More Effective Than Placebo for Ophthalmopathy

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Teprotumumab more effective for reducing proptosis, Clinical Activity Score, with rapid onset of effect