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Preoperative opioid use is associated with increased health care utilization and costs after elective abdominal surgery

Opioid Users Incur Higher Costs After Elective Abdominal Surgery

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Preoperative opioid use linked to increased likelihood of longer hospital stay, rate of 30-day readmission
Acetylsalicylic acid hyporesponsiveness after coronary artery bypass graft surgery can be overcome by multiple dosing

Multiple Dosing Mitigates ASA Hyporesponsiveness After CABG

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Multiple dosing more effective than ASA 81 or 325 mg once-daily for suppressing serum TXB2 formation
Regional exposure to televised direct-to-consumer advertising is associated with an increase in testosterone testing and new initiation

TV Ads for Testosterone Tied to Increased Testing, Tx in U.S. Men

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Increases in rates of new testing, testosterone initiation, initiation without a recent test
Neither vitamin E

Vitamin E, Selenium Don’t Prevent Dementia in Older Men

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No reduction in the incidence of dementia with supplements of vitamin E, selenium, or both
Pregabalin does not significantly reduce the intensity of leg pain associated with sciatica

Pregabalin Doesn’t Cut Intensity of Sciatica-Linked Leg Pain

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No significant difference in leg-pain intensity score at week eight or 52 for pregabalin, placebo
Xadago (safinamide) tablets have been approved by the U.S. Food and Drug Administration as an add-on drug to treat Parkinson's patients who take levodopa or carbidopa but experience "off" episodes.

FDA Approves New Parkinson’s Add-On Drug Xadago

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To help prevent 'off' episodes among users of levodopa/carbidopa
Oral

ω-3 Essential Fatty Acids May Protect Corneal Nerves in Dry Eye

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Pilot study shows ω-3 EFA supplementation is neuroprotective in patients with dry eye disease
For hepatitis C virus genotype 1 infection

Review: Multiple DAA Regimens Effective for HCV Genotype 1

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Six DAA regimens show high SVR in HCV genotype 1 without cirrhosis, even with HIV co-infection
For patients with chronic low back pain with active discopathy

Intradiscal Steroid Offers Short-Term Relief of Lower Back Pain

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Reduction in pain at one month, but not 12 months, for chronic low back pain with active discopathy
Prenatal docosahexaenoic acid supplementation does not affect IQ at age 7 years

Prenatal DHA Supplementation Doesn’t Increase IQ at Age 7

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No between-group difference in measures of language, academic and executive functioning