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Therapeutic inertia occurs in 19.1 percent of patients with type 2 diabetes with hemoglobin A1c ≥8 percent on two or more non-insulin antidiabetic drugs

Therapeutic Inertia in 19 Percent With T2DM, HbA1c ≥8 Percent

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HbA1c values of 8.0 to 9.9, >10 percent, diabetes duration ≥20 years linked to tx intensification

June 2017 Briefing – Pharmacy

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Here are what the editors at HealthDay consider to be the most important developments in Pharmacy for June 2017. This roundup includes the latest...
For small skin abscesses

Clindamycin, TMP-SMX Linked to Better Outcomes for Abscesses

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Clindamycin or trimethoprim-sulfamethoxazole ups short-term outcomes vs incision, drainage alone
Immediate antiretroviral initiation at HIV diagnosis is associated with greater bone mineral density declines compared with deferred initiation

In HIV, Greater BMD Decline for Immediate Versus Delayed ART

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After one year, change in bone mineral density was similar in the immediate and deferred groups
For well-trained cyclists

EPO Doping Has Little Effect on Real-World Cycling Performance

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Appears to improve high-intensity performance, not endurance or road race performance
Dutasteride for the treatment of benign prostatic hyperplasia may induce imbalance in metabolic function

Dutasteride Associated With Metabolic Safety Concerns

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Use of medication in BPH linked to higher hemoglobin A1c and LDL cholesterol levels
Many women at high risk for breast cancer do not take tamoxifen to prevent the disease

Many Women Have Questions, Concerns About Tamoxifen

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Study shows that normal symptoms of menopause are often attributed to tamoxifen
Depression

Psychological Risks Higher in Atopic Dermatitis Patients

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However, this does not translate into increased use of health care services, suicide
For select patients with advanced melanoma

Nivolumab Rx Beyond Progression Beneficial in Melanoma

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28 percent of patients treated beyond progression had lesion reduction >30 percent
Patients with remaining endogenous β-cell function after a decade of living with type 1 diabetes tend to have much higher levels of interleukin-35 than other patients with long-standing type 1 diabetes

T1DM Patients With Active β-Cell Function Differ Immunologically

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Findings for patients with remaining endogenous β-cell function after 10 or more years of T1DM